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Atsushi Kawase Selected Research

Visceral Pain

12/2022Discovery of pimozide derivatives as novel T-type calcium channel inhibitors with little binding affinity to dopamine D2 receptors for treatment of somatic and visceral pain.

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Atsushi Kawase Research Topics

Disease

11Inflammation (Inflammations)
11/2022 - 03/2013
7Arthritis (Polyarthritis)
10/2021 - 02/2007
7Neoplasms (Cancer)
03/2021 - 06/2003
5Breast Neoplasms (Breast Cancer)
03/2021 - 01/2009
4Experimental Arthritis
06/2018 - 02/2007
3Hepatocellular Carcinoma (Hepatoma)
08/2022 - 12/2014
3Liver Neoplasms (Liver Cancer)
03/2021 - 07/2019
2Cholestasis
08/2022 - 01/2019
2Drug-Related Side Effects and Adverse Reactions
07/2022 - 07/2022
2Infections
08/2014 - 01/2014
2Hypersensitivity (Allergy)
05/2008 - 04/2008
1Catalepsy
12/2022
1Intractable Pain
12/2022
1Visceral Pain
12/2022
1Chemical and Drug Induced Liver Injury
08/2022
1Leukemia
08/2022
1Rheumatoid Arthritis
02/2020
1Carcinoma (Carcinomatosis)
07/2019
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2019
1Fibrosis (Cirrhosis)
01/2019
1Hypercholesterolemia
07/2013
1Carcinogenesis
12/2010
1Melanoma (Melanoma, Malignant)
01/2010
1Contact Dermatitis (Eczema, Contact)
04/2008
1Rheumatic Diseases (Rheumatism)
08/2007

Drug/Important Bio-Agent (IBA)

8Proteins (Proteins, Gene)FDA Link
03/2021 - 01/2009
5EnzymesIBA
06/2018 - 02/2007
4radixinIBA
03/2021 - 12/2014
4Messenger RNA (mRNA)IBA
06/2015 - 02/2007
4Adenosine Triphosphate (ATP)IBA
12/2014 - 01/2009
3LipopolysaccharidesIBA
11/2022 - 01/2021
3Multidrug Resistance-Associated ProteinsIBA
03/2021 - 06/2015
3Member 1 Subfamily B ATP Binding Cassette TransporterIBA
03/2021 - 08/2007
3Peptides (Polypeptides)IBA
03/2021 - 06/2015
3Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA
06/2018 - 06/2015
3Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
06/2018 - 06/2015
3ATP-Binding Cassette Transporters (ABC Transporters)IBA
12/2014 - 01/2014
2Diclofenac (SR 38)FDA LinkGeneric
08/2022 - 01/2017
2GlucuronidesIBA
07/2022 - 07/2022
2AntiportersIBA
10/2021 - 01/2021
2Diphenhydramine (Benadryl)FDA LinkGeneric
10/2021 - 01/2021
2Small Interfering RNA (siRNA)IBA
03/2021 - 01/2019
2Prednisolone (Predate)FDA LinkGeneric
02/2020 - 04/2008
2Ibuprofen (Motrin)FDA LinkGeneric
11/2017 - 01/2017
2Anti-Allergic Agents (Antiallergic Agents)IBA
05/2008 - 04/2008
1Pimozide (Orap)FDA Link
12/2022
1Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
12/2022
1Protein Isoforms (Isoforms)IBA
12/2022
1T-Type Calcium Channels (T-Type Calcium Channel)IBA
12/2022
1HMGB1 Protein (HMG1)IBA
11/2022
1Dacarbazine (DIC)FDA LinkGeneric
08/2022
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
08/2022
1Memantine (Namenda)FDA Link
10/2021
12-methylcyclopentadienyl manganese tricarbonyl (MMT)IBA
10/2021
1moesinIBA
03/2021
1bisbenzimide ethoxide trihydrochloride (Hoechst 33342)IBA
03/2021
1ezrinIBA
03/2021
1PhosphoproteinsIBA
03/2021
1Protons (Proton)IBA
01/2021
1CationsIBA
01/2021
1Dexamethasone (Maxidex)FDA LinkGeneric
02/2020
1Methotrexate (Mexate)FDA LinkGeneric
07/2019
1Multidrug Resistance-Associated Protein 2IBA
01/2019
1phosphatidylinositol 4-phosphateIBA
01/2019
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
06/2018
14'-hydroxydiclofenacIBA
01/2017
1Hepatocyte Nuclear FactorsIBA
08/2016
1Liver X ReceptorsIBA
08/2016
1Amino Acid Transport Systems (Amino Acid Transporter)IBA
08/2016
1Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
08/2016
1Sodium-Glucose Transport ProteinsIBA
08/2016
1Sterol Regulatory Element Binding ProteinsIBA
08/2016
1AnionsIBA
06/2015
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
06/2015
1Rhodamine 123IBA
08/2014
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2014
1LDL CholesterolIBA
07/2013
1HDL CholesterolIBA
07/2013
1Flurbiprofen (Froben)FDA LinkGeneric
03/2013
1Blood Proteins (Serum Proteins)IBA
03/2013
1Propranolol (Inderal)FDA LinkGeneric
03/2013
1MicroRNAs (MicroRNA)IBA
05/2011
1CarcinogensIBA
12/2010
1phytoncideIBA
01/2010
1SolutionsIBA
01/2010
1Monophenol Monooxygenase (Tyrosinase)IBA
01/2010
1Melanins (Melanin)IBA
01/2010
1Nitrofurantoin (Macrodantin)FDA LinkGeneric
01/2009
1FlavonoidsIBA
01/2009
1chrysinIBA
01/2009
1Ethanol (Ethyl Alcohol)IBA
05/2008
1Picryl Chloride (Trinitrochlorobenzene)IBA
04/2008
1Cytochrome P-450 CYP3AIBA
08/2007
1BilirubinIBA
02/2007
1Fluorescein (Funduscein)FDA LinkGeneric
06/2003
1polyanionsIBA
06/2003
1DNA (Deoxyribonucleic Acid)IBA
06/2003

Therapy/Procedure

2Ligation
08/2022 - 01/2019
1Intravenous Administration
01/2017
1Therapeutics
12/2010