Edwin Jousma Selected Research

mirdametinib

10/2015	Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of Neurofibromatosis type 1.
1/2013	MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.

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Edwin Jousma Research Topics

Disease

7	Neurofibroma 01/2019 - 02/2012
5	Neoplasms (Cancer) 01/2019 - 02/2012
1	Carcinogenesis 03/2016
1	Neurofibromatosis 1 (Neurofibromatosis Type I) 10/2015
1	Peripheral Nervous System Neoplasms 01/2013
1	Neurofibromatoses (Neurofibromatosis) 01/2013
1	Neurofibrosarcoma (MPNST) 01/2013
1	Plexiform Neurofibroma 02/2012
1	Poisoning 01/2009
1	Seizures (Absence Seizure) 01/2009

Drug/Important Bio-Agent (IBA)

2	CytokinesIBA 01/2019 - 01/2017
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 10/2015
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2015 - 01/2013
2	mirdametinibIBA 10/2015 - 01/2013
1	FLLL 32IBA 01/2019
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2019
1	Conditioned Culture MediaIBA 01/2017
1	Polyethylene (Polythene)IBA 01/2017
1	Interferon Type IIBA 01/2017
1	CateninsIBA 03/2016
1	Histones (Histone)IBA 03/2016
1	ras GTPase-Activating Proteins (ras-GAP)IBA 10/2015
1	Guanosine Triphosphate (GTP)IBA 10/2015
1	Phosphotransferases (Kinase)IBA 01/2013
1	pexidartinibIBA 01/2013
1	Everolimus FDA Link 02/2012
1	Therapeutic UsesIBA 02/2012
1	Sorafenib (BAY 43-9006)FDA Link 02/2012
1	Atropine FDA LinkGeneric 01/2009
1	asoxime chloride (H16)IBA 01/2009
1	Cholinergic Antagonists (Anticholinergics)IBA 01/2009
1	AcetylcholinesteraseIBA 01/2009
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2009
1	Olanzapine (Zyprexa)FDA Link 01/2009
1	SomanIBA 01/2009
1	OrganophosphatesIBA 01/2009
1	OximesIBA 01/2009
1	Bromodeoxyuridine (BrdU)IBA 01/2009

Therapy/Procedure

2	Therapeutics 01/2013 - 02/2012
1	Transplantation 03/2016