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Thomas A Jongens Selected Research

Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)

1/2015PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndrome.
3/2011Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment.
6/2010Age-dependent cognitive impairment in a Drosophila fragile X model and its pharmacological rescue.

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Thomas A Jongens Research Topics

Disease

5Fragile X Syndrome (Martin Bell Syndrome)
01/2024 - 02/2004
4Cognitive Dysfunction
01/2015 - 06/2010
2Intellectual Disability (Idiocy)
03/2005 - 06/2002
1Autistic Disorder (Autism)
10/2022
1Starvation
01/2018
1Memory Disorders (Memory Loss)
06/2010
1Inborn Genetic Diseases (Disease, Hereditary)
06/2002

Drug/Important Bio-Agent (IBA)

3LithiumIBA
01/2015 - 06/2010
3Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
01/2015 - 06/2010
2Insulin (Novolin)FDA Link
01/2024 - 01/2018
1Cell Adhesion MoleculesIBA
10/2022
1LipidsIBA
01/2018
1CarbohydratesIBA
01/2018
1RibonucleoproteinsIBA
03/2005
1Proteins (Proteins, Gene)FDA Link
03/2005
1Fragile X Mental Retardation ProteinIBA
02/2004
1RNA-Binding Proteins (RNA-Binding Protein)IBA
06/2002

Therapy/Procedure

3Therapeutics
09/2014 - 09/2012