Su-Hyun Jo Selected Research

Torsades de Pointes (Torsade de Pointes)

9/2013	Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel.
4/2010	Block of the human ether-a-go-go-related gene (hERG) K+ channel by the antidepressant desipramine.
11/2009	H(1) antihistamine drug promethazine directly blocks hERG K(+) channel.
9/2008	Clomipramine block of the hERG K+ channel: accessibility to F656 and Y652.
1/2008	Protriptyline block of the human ether-à-go-go-related gene (HERG) K+ channel.
4/2007	Maprotiline block of the human ether-a-go-go-related gene (HERG) K+ channel.
8/2006	Blockade of HERG human K+ channel and IKr of guinea pig cardiomyocytes by prochlorperazine.
6/2006	Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine.
5/2005	Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine.
5/2004	Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine.

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Su-Hyun Jo Research Topics

Disease

10	Torsades de Pointes (Torsade de Pointes) 09/2013 - 05/2004
6	Long QT Syndrome 02/2013 - 09/2008
5	Sudden Death 01/2008 - 05/2004
4	Mental Disorders (Mental Disorder) 04/2010 - 08/2006
2	Nausea 01/2023 - 08/2006
2	Vomiting 01/2023 - 08/2006
2	Cardiac Arrhythmias (Arrythmia) 01/2023 - 08/2011
2	Cardiovascular Diseases (Cardiovascular Disease) 03/2015 - 08/2011
2	Neoplasms (Cancer) 12/2014 - 12/2009
2	Astrocytoma (Pilocytic Astrocytoma) 11/2014 - 01/2010
1	Atrial Fibrillation 01/2023
1	Panic Disorder (Panic Attack) 12/2021
1	Sialadenitis 01/2017
1	Heart Diseases (Heart Disease) 03/2015
1	Neuroinflammatory Diseases 11/2014
1	Cardiomegaly (Heart Hypertrophy) 01/2014
1	Hypertrophy 01/2014
1	Glioma (Gliomas) 01/2010
1	Xerostomia 08/2009
1	Acidosis 01/2005
1	Hypoxia (Hypoxemia) 01/2005
1	Ischemia 03/2003
1	Myocardial Infarction 03/2003

Drug/Important Bio-Agent (IBA)

7	Ether (Diethyl Ether)IBA 02/2013 - 09/2008
3	CytokinesIBA 01/2017 - 01/2010
3	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 04/2010 - 01/2008
3	Antipsychotic Agents (Antipsychotics)IBA 06/2006 - 05/2004
2	Histamine H1 Receptors (Histamine H1 Receptor)IBA 01/2023 - 08/2009
2	Histamine Antagonists (Antihistamines)IBA 01/2023 - 08/2009
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017 - 01/2010
2	BradykininIBA 01/2017 - 01/2010
2	Analgesics (Analgesic Drugs)IBA 12/2014 - 12/2009
2	Histamine (Histamine Dihydrochloride)FDA Link 09/2013 - 08/2009
2	Chlorpheniramine (Chlorphenamine)FDA LinkGeneric 08/2009 - 06/2009
1	Dimenhydrinate (DMH)FDA LinkGeneric 01/2023
1	Ion Channels (Ion Channel)IBA 01/2023
1	Histamine H1 AntagonistsIBA 01/2023
1	Paroxetine (Paxil)FDA LinkGeneric 12/2021
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 12/2021
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2015
1	Nitric Oxide Synthase (NO Synthase)IBA 03/2015
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 03/2015
1	Peptides (Polypeptides)IBA 12/2014
1	crotamineIBA 12/2014
1	Toll-Like Receptor 3IBA 11/2014
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 11/2014
1	ProstaglandinsIBA 11/2014
1	Pattern Recognition ReceptorsIBA 11/2014
1	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2014
1	Angiotensin IIIBA 01/2014
1	TRPC6 Cation ChannelIBA 01/2014
1	Endothelin-1 (Endothelin 1)IBA 01/2014
1	Anti-Asthmatic Agents (Antiasthmatic Drugs)IBA 09/2013
1	Anti-Allergic Agents (Antiallergic Agents)IBA 09/2013
1	azelastine (Optivar)FDA LinkGeneric 09/2013
1	Fluphenazine (Prolixin)FDA LinkGeneric 02/2013
1	Desipramine (Pertofrane)FDA LinkGeneric 04/2010
1	2,5-dichloro-4-bromophenol (B 2)IBA 01/2010
1	ZymosanIBA 01/2010
1	AntidotesIBA 12/2009
1	phenothiazineIBA 11/2009
1	Hypnotics and Sedatives (Sedatives)IBA 11/2009
1	AntiemeticsIBA 11/2009
1	Cholinergic Antagonists (Anticholinergics)IBA 11/2009
1	Promethazine (Promet)FDA LinkGeneric 11/2009
1	Histamine Receptors (Histamine Receptor)IBA 08/2009
1	EnzymesIBA 08/2009
1	Carbachol (Carbastat)FDA Link 08/2009
1	AstemizoleIBA 08/2009
1	Muscarinic AntagonistsIBA 08/2009
1	Clomipramine (Anafranil)FDA LinkGeneric 09/2008
1	Protriptyline (Vivactil)FDA LinkGeneric 01/2008
1	Antidepressive Agents (Antidepressants)IBA 04/2007
1	Maprotiline (Ludiomil)FDA Link 04/2007
1	Prochlorperazine (Compazine)FDA LinkGeneric 08/2006
1	Clozapine (Clozaril)FDA LinkGeneric 06/2006
1	Trifluoperazine (Stelazine)FDA LinkGeneric 05/2005
1	p38 Mitogen-Activated Protein KinasesIBA 01/2005
1	Chlorpromazine (Thorazine)FDA Link 05/2004
1	Diazoxide (Hyperstat)FDA Link 03/2003
1	MCC 134IBA 03/2003

Therapy/Procedure

1	Therapeutics 06/2010
1	Traditional Medicine (Folk Remedies) 12/2009