Jennifer B Jacob Selected Research

Neoplasms (Cancer)

1/2021	Review of immune checkpoint inhibitors in immuno-oncology.
7/2019	An HER2 DNA vaccine with evolution-selected amino acid substitutions reveals a fundamental principle for cancer vaccine formulation in HER2 transgenic mice.
12/2012	Induction of proapoptotic antibodies to triple-negative breast cancer by vaccination with TRAIL death receptor DR5 DNA.
1/2010	Combining human and rat sequences in her-2 DNA vaccines blunts immune tolerance and drives antitumor immunity.
9/2009	Autoimmune thyroiditis as an indicator of autoimmune sequelae during cancer immunotherapy.
5/2009	Her-2 DNA versus cell vaccine: immunogenicity and anti-tumor activity.
5/2009	Tumor regression following DNA vaccination and regulatory T cell depletion in neu transgenic mice leads to an increased risk for autoimmunity.
9/2008	DNA vaccination controls Her-2+ tumors that are refractory to targeted therapies.
7/2007	Control of Her-2 tumor immunity and thyroid autoimmunity by MHC and regulatory T cells.
9/2005	Concurrent induction of antitumor immunity and autoimmune thyroiditis in CD4+ CD25+ regulatory T cell-depleted mice.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Jennifer B Jacob Research Topics

Disease

10	Neoplasms (Cancer) 01/2021 - 09/2005
2	Breast Neoplasms (Breast Cancer) 04/2023 - 09/2009
2	Autoimmune Thyroiditis (Lymphomatous Thyroiditis) 09/2009 - 07/2007
1	Melanoma (Melanoma, Malignant) 01/2021
1	Triple Negative Breast Neoplasms 12/2012
1	Thyroiditis 09/2009
1	Carcinogenesis 05/2009
1	Autoimmune Diseases (Autoimmune Disease) 07/2007

Drug/Important Bio-Agent (IBA)

5	AutoantigensIBA 01/2021 - 09/2005
5	DNA (Deoxyribonucleic Acid)IBA 12/2012 - 09/2008
4	AntibodiesIBA 01/2021 - 09/2005
4	VaccinesIBA 07/2019 - 05/2009
4	Thyroglobulin FDA Link 09/2009 - 09/2005
2	DNA VaccinesIBA 01/2010 - 05/2009
2	EpitopesIBA 01/2010 - 09/2008
2	AntigensIBA 01/2010 - 09/2005
2	Indicators and Reagents (Reagents)IBA 09/2009 - 05/2009
1	LigandsIBA 01/2021
1	Immunoglobulin G (IgG)IBA 12/2012
1	Death Domain ReceptorsIBA 12/2012
1	TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA 12/2012
1	Heterophile AntigensIBA 01/2010
1	Cancer VaccinesIBA 01/2010
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 09/2008
1	Gefitinib (Iressa)FDA Link 09/2008
1	Proteasome Endopeptidase Complex (Proteasome)IBA 09/2008
1	HLA-DRB1*03:01 antigenIBA 07/2007
1	Immunomodulating AgentsIBA 09/2005

Therapy/Procedure

5	Immunotherapy 01/2021 - 09/2005
3	Therapeutics 04/2023 - 09/2008
1	Injections 09/2009