Hirohito Ishigaki Selected Research

Vaccines

1/2022	Inactivated whole influenza virus particle vaccines induce neutralizing antibodies with an increase in immunoglobulin gene subclones of B-lymphocytes in cynomolgus macaques.
1/2021	Potent priming by inactivated whole influenza virus particle vaccines is linked to viral RNA uptake into antigen presenting cells.
1/2021	Neutralizing antibody-dependent and -independent immune responses against SARS-CoV-2 in cynomolgus macaques.
12/2016	Vaccination against H9N2 avian influenza virus reduces bronchus-associated lymphoid tissue formation in cynomolgus macaques after intranasal virus challenge infection.
11/2016	Sensitization with vaccinia virus encoding H5N1 hemagglutinin restores immune potential against H5N1 influenza virus.
1/2013	Protection against H5N1 highly pathogenic avian and pandemic (H1N1) 2009 influenza virus infection in cynomolgus monkeys by an inactivated H5N1 whole particle vaccine.
1/2012	Memory immune responses against pandemic (H1N1) 2009 influenza virus induced by a whole particle vaccine in cynomolgus monkeys carrying Mafa-A1*052:02.
2/2010	Amelioration of pneumonia with Streptococcus pneumoniae infection by inoculation with a vaccine against highly pathogenic avian influenza virus in a non-human primate mixed infection model.
1/2010	Subcutaneous inoculation of a whole virus particle vaccine prepared from a non-pathogenic virus library induces protective immunity against H7N7 highly pathogenic avian influenza virus in cynomolgus macaques.
12/2009	Intranasal administration of a live non-pathogenic avian H5N1 influenza virus from a virus library confers protective immunity against H5N1 highly pathogenic avian influenza virus infection in mice: comparison of formulations and administration routes of vaccines.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Hirohito Ishigaki Research Topics

Disease

18	Infections 01/2024 - 06/2007
11	Influenza in Birds (Avian Flu) 01/2021 - 12/2009
8	Neoplasms (Cancer) 03/2022 - 01/2006
6	Virus Diseases (Viral Diseases) 11/2019 - 12/2009
5	COVID-19 01/2024 - 01/2021
5	Human Influenza (Influenza) 01/2022 - 01/2013
4	Inflammation (Inflammations) 10/2023 - 01/2021
4	Infertility (Sterility) 11/2020 - 10/2019
3	Viral Pneumonia 01/2021 - 01/2017
2	Fever (Fevers) 01/2023 - 11/2010
2	Severe Acute Respiratory Syndrome 01/2022 - 01/2021
2	Pneumonia (Pneumonitis) 11/2021 - 02/2010
2	Disease Progression 01/2021 - 06/2014
2	Polyps 10/2019 - 12/2018
2	Body Weight (Weight, Body) 08/2014 - 11/2011
1	Rheumatoid Arthritis 01/2024
1	Experimental Arthritis 01/2024
1	Critical Illness (Critically Ill) 10/2023
1	Thrombosis (Thrombus) 10/2023
1	Fibrosis (Cirrhosis) 01/2022
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2021
1	Teratoma (Teratoid Tumor) 01/2021
1	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 11/2020
1	Atrophy 01/2020
1	Lung Injury 01/2020
1	Carcinoma (Carcinomatosis) 12/2018
1	Non-Muscle Invasive Bladder Neoplasms 01/2018
1	Glioblastoma (Glioblastoma Multiforme) 11/2017
1	Embryonal Carcinoma 11/2017
1	Anaphylaxis (Anaphylactic Shock) 01/2017
1	Hypersensitivity (Allergy) 01/2017
1	Vaccinia 11/2016
1	Body Temperature Changes 08/2014

Drug/Important Bio-Agent (IBA)

10	VaccinesIBA 01/2022 - 12/2009
5	Neuraminidase (Sialidase)IBA 11/2021 - 08/2014
5	Antiviral Agents (Antivirals)IBA 11/2021 - 06/2014
4	Interleukin-6 (Interleukin 6)IBA 01/2024 - 11/2010
4	Neutralizing AntibodiesIBA 12/2022 - 08/2009
4	CytokinesIBA 11/2019 - 01/2013
3	Peptides (Polypeptides)IBA 11/2021 - 06/2007
2	Immunoglobulin G (IgG)IBA 01/2024 - 11/2017
2	Monoclonal AntibodiesIBA 10/2023 - 06/2014
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2021
2	Formaldehyde (Formol)FDA Link 01/2022 - 12/2016
2	Influenza Vaccines (Influenza Vaccine)FDA Link 01/2022 - 01/2017
2	Ether (Diethyl Ether)IBA 01/2022 - 01/2021
2	Zanamivir (Relenza)FDA Link 11/2021 - 01/2021
2	Oseltamivir (Tamiflu)FDA Link 11/2021 - 01/2021
2	Interferon-alpha (Interferon Alfa)IBA 01/2021 - 01/2020
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 08/2014
2	InterferonsIBA 01/2021 - 08/2014
2	Interleukin-13IBA 01/2021 - 01/2017
2	Proton Pump InhibitorsIBA 10/2019 - 12/2018
2	peramivirIBA 08/2014 - 11/2011
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2008 - 01/2006
1	NAD (NADH)IBA 01/2024
1	CollagenIBA 01/2024
1	Antirheumatic Agents (DMARD)IBA 01/2024
1	FibrinIBA 01/2024
1	EnzymesIBA 01/2024
1	Messenger RNA (mRNA)IBA 01/2024
1	EpitopesIBA 01/2024
1	Dichlororibofuranosylbenzimidazole (DRB)IBA 01/2024
1	Amino Acids FDA Link 01/2024
1	Complement Factor D (Factor D)IBA 10/2023
1	Complement Factor B (Factor B)IBA 10/2023
1	Complement System Proteins (Complement)IBA 10/2023
1	ProteomeIBA 10/2023
1	Indomethacin (Indometacin)FDA LinkGeneric 01/2023
1	Cyclooxygenase InhibitorsIBA 01/2023
1	ProstaglandinsIBA 01/2023
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2023
1	Smallpox Vaccine (Vaccine, Smallpox)FDA Link 01/2022
1	Angiotensin-Converting Enzyme 2IBA 01/2022
1	Propiolactone FDA Link 01/2022
1	Viral Envelope ProteinsIBA 11/2021
1	Hemagglutinins (Hemagglutinin)IBA 11/2021
1	Detergents (Detergent)IBA 01/2021
1	Viral RNAIBA 01/2021
1	Pattern Recognition ReceptorsIBA 01/2021
1	Immune Checkpoint ProteinsIBA 01/2021
1	baloxavirIBA 01/2021
1	EndonucleasesIBA 01/2021
1	AntibodiesIBA 11/2020
1	Clarithromycin (Biaxin)FDA LinkGeneric 11/2019
1	MacrolidesIBA 11/2019
1	AutoantibodiesIBA 11/2017
1	glucose-regulated proteinsIBA 11/2017
1	Immunoglobulin E (IgE)IBA 01/2017
1	Immunoglobulin A (IgA)IBA 01/2017
1	avian influenza A virus hemagglutininIBA 11/2016
1	Interferon-gamma (Interferon, gamma)IBA 08/2014

Therapy/Procedure

7	Transplantation 03/2022 - 11/2017
5	Therapeutics 03/2022 - 06/2014
2	Intranasal Administration 01/2017 - 12/2009
1	Autologous Transplantation 01/2021
1	Immunotherapy 01/2020
1	Hysterectomy 01/2020
1	Transurethral Resection of Bladder 01/2018
1	Intravenous Administration 08/2014