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David M Irwin Selected Research

Zinc Finger Nucleases

1/2013An over expression APP model for anti-Alzheimer disease drug screening created by zinc finger nuclease technology.

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David M Irwin Research Topics

Disease

8Neoplasms (Cancer)
01/2024 - 03/2014
4Neoplasm Metastasis (Metastasis)
01/2024 - 05/2015
4Insulin Resistance
01/2017 - 06/2009
3Infections
01/2023 - 01/2016
3Ovarian Epithelial Carcinoma
04/2022 - 01/2018
3Ovarian Neoplasms (Ovarian Cancer)
01/2020 - 01/2018
3Breast Neoplasms (Breast Cancer)
01/2019 - 01/2015
3Hyperglycemia
01/2014 - 12/2012
2Influenza in Birds (Avian Flu)
01/2023 - 01/2020
2Type 2 Diabetes Mellitus (MODY)
01/2016 - 06/2009
2Hypoxia (Hypoxemia)
11/2015 - 11/2012
2Type 2 Maturity-Onset Diabetes of the Young
03/2013 - 03/2011
1Disease Resistance
01/2023
1Wounds and Injuries (Trauma)
10/2019
1Circulating Neoplastic Cells
01/2018
1Gestational Diabetes (Gestational Diabetes Mellitus)
01/2017
1Hypoglycemia (Reactive Hypoglycemia)
01/2017
1Heart Failure
11/2016
1Cardiomyopathies (Cardiomyopathy)
11/2016
1Cardiotoxicity
11/2016
1Inflammation (Inflammations)
01/2015
1Diabetic Cardiomyopathies
01/2014
1Alzheimer Disease (Alzheimer's Disease)
01/2013
1Carcinogenesis
01/2012
1Mason-Type Diabetes
03/2011
1Body Weight (Weight, Body)
03/2011
1Obesity
06/2009

Drug/Important Bio-Agent (IBA)

5Proteins (Proteins, Gene)FDA Link
01/2020 - 06/2009
4GlucokinaseIBA
01/2014 - 03/2011
3ResistinIBA
01/2015 - 06/2009
2Epithelial Cell Adhesion MoleculeIBA
04/2022 - 01/2015
2Interleukin-6 (Interleukin 6)IBA
01/2019 - 05/2015
2Insulin (Novolin)FDA Link
01/2017 - 03/2011
2Oxygen (Dioxygen)IBA
11/2015 - 11/2012
2Liver GlycogenIBA
03/2013 - 06/2009
2GlycogenIBA
12/2012 - 06/2009
2Glucose (Dextrose)FDA LinkGeneric
12/2012 - 06/2009
1Small Interfering RNA (siRNA)IBA
01/2024
1Anti-Bacterial Agents (Antibiotics)IBA
01/2023
1Hemagglutinins (Hemagglutinin)IBA
01/2020
1Codon (Codons)IBA
01/2020
1Messenger RNA (mRNA)IBA
01/2020
1Neuraminidase (Sialidase)IBA
01/2020
1Streptozocin (Streptozotocin)FDA Link
10/2019
1SuspensionsIBA
10/2019
1Biomarkers (Surrogate Marker)IBA
01/2018
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
01/2018
1AntigensIBA
01/2018
1Keratins (Keratin)IBA
10/2017
1Serum-Free Culture MediaIBA
10/2017
1Glyburide (Glibenclamide)FDA LinkGeneric
01/2017
1Palmitic Acid (Hexadecanoic Acid)IBA
01/2017
1Epirubicin (Ellence)FDA LinkGeneric
11/2016
1xinmailongIBA
11/2016
1p38 Mitogen-Activated Protein KinasesIBA
11/2016
1Interferon-gamma (Interferon, gamma)IBA
01/2016
1Mitochondrial DNA (mtDNA)IBA
01/2016
1CytokinesIBA
01/2016
1StaurosporineIBA
01/2015
1Hormones (Hormone)IBA
01/2015
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
03/2014
1NADPH Oxidases (NAD(P)H oxidase)IBA
01/2014
1Rosiglitazone (Avandia)FDA Link
01/2014
1Insulin ReceptorIBA
01/2014
1Zinc Finger NucleasesIBA
01/2013
1Cyclin D1IBA
01/2012
1ChromatinIBA
01/2012
1Blood Glucose (Blood Sugar)IBA
03/2011
1CreatinineIBA
03/2011

Therapy/Procedure

6Drug Therapy (Chemotherapy)
01/2020 - 01/2015
1Transplantation
05/2015