Atsuhiro Ichihara Selected Research

Peptides (Polypeptides)

1/2011	Podocytes as a target of prorenin in diabetes.
3/2010	Possible roles of human (pro)renin receptor suggested by recent clinical and experimental findings.
1/2010	Functional characterization of the decoy peptide, [R10P]IFLKRMPSI[19P].
1/2009	Drug discovery for overcoming chronic kidney disease (CKD): new therapy for CKD by a (pro)renin-receptor-blocking decoy peptide.
6/2008	Involvement of (pro)renin receptor in the glomerular filtration barrier.
5/2008	Pathologic roles of prorenin and (pro)renin receptor in the eye.
9/2007	The (pro)renin receptor and the kidney.
6/2007	Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats.
1/2007	Role of nonproteolytically activated prorenin in pathologic, but not physiologic, retinal neovascularization.
10/2006	Prorenin receptor blockers: effects on cardiovascular complications of diabetes and hypertension.

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Atsuhiro Ichihara Research Topics

Disease

33	Hypertension (High Blood Pressure) 01/2023 - 05/2006
17	Hyperaldosteronism (Conn Syndrome) 03/2024 - 04/2012
11	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 11/2008
9	Proteinuria 08/2022 - 09/2006
9	Inflammation (Inflammations) 09/2019 - 06/2006
9	Diabetic Nephropathies (Diabetic Nephropathy) 11/2014 - 06/2003
7	Neoplasms (Cancer) 01/2023 - 01/2007
6	Essential Hypertension 01/2017 - 06/2008
5	Adenoma (Adenomas) 12/2023 - 12/2019
5	Pre-Eclampsia (Preeclampsia) 01/2023 - 01/2016
5	Fibrosis (Cirrhosis) 01/2020 - 05/2006
5	Chronic Renal Insufficiency 06/2018 - 01/2009
4	Cushing Syndrome 09/2023 - 01/2019
4	Insulin Resistance 01/2023 - 09/2009
4	Type 2 Diabetes Mellitus (MODY) 01/2023 - 08/2002
4	Arteriosclerosis 10/2022 - 11/2008
4	Diabetes Mellitus 01/2020 - 12/2013
4	Albuminuria 01/2011 - 12/2009
3	Obesity 01/2023 - 01/2014
3	Hypoxia (Hypoxemia) 01/2020 - 03/2018
3	Heart Failure 01/2020 - 07/2010
3	Paraganglioma (Paragangliomas) 12/2019 - 04/2013
3	Pheochromocytoma 12/2019 - 04/2013
3	Edema (Dropsy) 01/2018 - 11/2004
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2018 - 09/2008
3	Renal Insufficiency (Renal Failure) 12/2011 - 11/2008
3	Stroke (Strokes) 01/2008 - 05/2006
3	AIDS-Related Complex (ARC) 11/2003 - 02/2002
2	COVID-19 03/2024 - 10/2020
2	Pituitary Neoplasms (Pituitary Adenoma) 02/2024 - 01/2022
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2023 - 11/2014
2	Osteoporosis 10/2022 - 01/2015
2	Graves Disease (Basedow Disease) 05/2021 - 01/2018
2	Hypopituitarism (Sheehan's Syndrome) 01/2020 - 01/2018
2	Choroidal Neovascularization 09/2019 - 12/2008
2	Macular Degeneration (Age-Related Maculopathy) 09/2019 - 12/2008
2	Neurogenic Diabetes Insipidus (Central Diabetes Insipidus) 01/2018 - 01/2017
2	Atherosclerosis 01/2016 - 08/2010
2	Gestational Diabetes (Gestational Diabetes Mellitus) 12/2014 - 06/2013
2	Hyperglycemia 11/2014 - 10/2004
2	Body Weight (Weight, Body) 01/2014 - 01/2014
2	Sepsis (Septicemia) 01/2014 - 10/2000
2	Dyslipidemias (Dyslipidemia) 01/2013 - 05/2005
2	Hypercholesterolemia 01/2013 - 03/2012

Drug/Important Bio-Agent (IBA)

45	Prorenin ReceptorIBA 01/2023 - 05/2006
32	ReninIBA 01/2022 - 02/2002
14	Peptides (Polypeptides)IBA 01/2011 - 10/2004
10	AldosteroneIBA 12/2023 - 04/2012
8	SaltsIBA 11/2020 - 11/2004
6	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2007
6	Angiotensin IIIBA 02/2014 - 06/2007
5	AngiotensinsIBA 01/2023 - 11/2003
5	Small Interfering RNA (siRNA)IBA 01/2020 - 03/2015
5	Streptozocin (Streptozotocin)FDA Link 09/2008 - 06/2003
4	Biomarkers (Surrogate Marker)IBA 03/2024 - 11/2008
4	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 03/2024 - 01/2020
4	Hydrocortisone (Cortisol)FDA LinkGeneric 09/2023 - 01/2019
4	esaxerenoneIBA 08/2022 - 01/2021
4	Antihypertensive Agents (Antihypertensives)IBA 10/2020 - 08/2010
4	CatecholaminesIBA 01/2020 - 12/2014
3	Mineralocorticoid Receptor AntagonistsIBA 03/2024 - 01/2022
3	aliskiren FDA Link 01/2023 - 05/2010
3	Amlodipine (Norvasc)FDA LinkGeneric 01/2023 - 01/2009
3	Glucose (Dextrose)FDA LinkGeneric 10/2022 - 10/2002
3	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 10/2020 - 06/2007
3	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2019 - 07/2016
3	SodiumIBA 12/2017 - 05/2010
3	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 12/2014 - 08/2010
3	Fluvastatin FDA Link 01/2013 - 08/2002
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2024 - 01/2023
2	Indicators and Reagents (Reagents)IBA 03/2024 - 01/2016
2	C-Reactive ProteinIBA 11/2023 - 12/2019
2	AngiotensinogenIBA 01/2023 - 11/2003
2	EnzymesIBA 01/2023 - 01/2020
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2023 - 11/2014
2	Hormones (Hormone)IBA 01/2023 - 01/2018
2	Growth Hormone (Somatotropin)IBA 01/2022 - 03/2018
2	Angiotensin Receptor AntagonistsIBA 10/2020 - 01/2011
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 10/2020 - 12/2007
2	CholesterolIBA 01/2020 - 01/2007
2	alpha-Methyltyrosine (Metirosine)FDA Link 12/2019 - 03/2018
2	AlbuminsIBA 12/2019 - 12/2014
2	CateninsIBA 10/2019 - 03/2015
2	GlucocorticoidsIBA 01/2019 - 01/2017
2	Triglycerides (Triacylglycerol)IBA 01/2018 - 03/2012
2	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2017 - 12/2014
2	Insulin-Like Growth Factor I (IGF-1)IBA 01/2014 - 01/2014
2	LipidsIBA 03/2012 - 08/2002
2	FructoseIBA 01/2011 - 09/2009
2	candesartanIBA 08/2010 - 11/2003
2	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 12/2009 - 01/2009
2	Retinaldehyde (Retinal)IBA 07/2009 - 05/2008
2	Messenger RNA (mRNA)IBA 01/2009 - 05/2006
2	Type 1 Angiotensin ReceptorIBA 12/2008 - 05/2008

Therapy/Procedure

19	Therapeutics 05/2021 - 08/2004
11	Renal Dialysis (Hemodialysis) 01/2023 - 05/2005
2	Kidney Transplantation 01/2021 - 05/2018
2	Radiotherapy 12/2020 - 01/2020
2	Adrenalectomy 05/2018 - 12/2017
2	Nephrectomy 05/2010 - 01/2007