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Hai Huang Selected Research

Cisplatin (Platino)

12/2022Glutathione-sensitive nanoparticles enhance the combined therapeutic effect of checkpoint kinase 1 inhibitor and cisplatin in prostate cancer.
9/2022Poly(β-cyclodextrin)/platinum prodrug supramolecular nano system for enhanced cancer therapy: Synthesis and in vivo study.
11/2020Nitric oxide-releasing platinum(IV) prodrug efficiently inhibits proliferation and metastasis of cancer cells.
11/2019A polyprodrug-based nanoplatform for cisplatin prodrug delivery and combination cancer therapy.
4/2019Modular design of nanobody-drug conjugates for targeted-delivery of platinum anticancer drugs with an MRI contrast agent.
1/2019Targeting an Autocrine Regulatory Loop in Cancer Stem-like Cells Impairs the Progression and Chemotherapy Resistance of Bladder Cancer.
1/2017Effects of Chinese Medicine as Adjunct Medication for Adjuvant Chemotherapy Treatments of Non-Small Cell Lung Cancer Patients.
1/2015RLN2 Is a Positive Regulator of AKT-2-Induced Gene Expression Required for Osteosarcoma Cells Invasion and Chemoresistance.
8/2014Secreted clusterin (sCLU) regulates cell proliferation and chemosensitivity to cisplatin by modulating ERK1/2 signals in human osteosarcoma cells.
2/2014Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell-like side population cells.

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Hai Huang Research Topics

Disease

135Neoplasms (Cancer)
05/2024 - 11/2002
64Prostatic Neoplasms (Prostate Cancer)
05/2024 - 10/2005
36Neoplasm Metastasis (Metastasis)
12/2023 - 05/2008
27Inflammation (Inflammations)
03/2024 - 06/2008
17Hepatocellular Carcinoma (Hepatoma)
01/2023 - 06/2012
17Infections
01/2023 - 08/2006
16Carcinogenesis
02/2024 - 09/2011
13Ischemia
12/2020 - 06/2008
12Renal Cell Carcinoma (Grawitz Tumor)
02/2024 - 04/2013
12Urinary Bladder Neoplasms (Bladder Cancer)
01/2023 - 05/2008
11Hypoxia (Hypoxemia)
10/2021 - 12/2008
10Fibrosis (Cirrhosis)
01/2024 - 01/2006
10Stomach Neoplasms (Stomach Cancer)
12/2023 - 06/2011
9Colorectal Neoplasms (Colorectal Cancer)
05/2024 - 02/2015
9Osteosarcoma (Osteogenic Sarcoma)
12/2023 - 08/2014
9Pain (Aches)
10/2023 - 03/2014
9Carcinoma (Carcinomatosis)
01/2023 - 05/2008
8Wounds and Injuries (Trauma)
01/2024 - 03/2014
8Reperfusion Injury
01/2019 - 06/2008
6COVID-19
04/2024 - 01/2020
6Pneumonia (Pneumonitis)
09/2023 - 06/2010
6Osteoporosis
01/2022 - 04/2018
6Lung Neoplasms (Lung Cancer)
10/2021 - 01/2014
5Liver Cirrhosis (Hepatic Cirrhosis)
01/2024 - 05/2010
5Postoperative Pain
12/2023 - 10/2012
5Body Weight (Weight, Body)
10/2023 - 04/2013
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2022 - 01/2014
5Virus Diseases (Viral Diseases)
01/2022 - 08/2006
5Lymphatic Metastasis
01/2021 - 04/2016
5Human Influenza (Influenza)
05/2015 - 06/2010
4Adenocarcinoma
03/2023 - 02/2016
4Breast Neoplasms (Breast Cancer)
02/2023 - 12/2016
4Viral Pneumonia
11/2022 - 12/2013
4Chronic Hepatitis B
01/2022 - 02/2006
4Melanoma (Melanoma, Malignant)
01/2021 - 01/2020
4Lung Injury
07/2015 - 09/2011
4Pancreatic Neoplasms (Pancreatic Cancer)
12/2014 - 04/2009
3Cardiac Arrhythmias (Arrythmia)
03/2024 - 01/2012
3Knee Osteoarthritis
03/2024 - 01/2022

Drug/Important Bio-Agent (IBA)

49Proteins (Proteins, Gene)FDA Link
02/2024 - 11/2002
23Biomarkers (Surrogate Marker)IBA
11/2023 - 07/2010
12AndrogensIBA
01/2024 - 01/2016
12Therapeutic UsesIBA
05/2023 - 06/2010
11DNA (Deoxyribonucleic Acid)IBA
01/2022 - 11/2005
11Small Interfering RNA (siRNA)IBA
01/2020 - 09/2011
11HMGB1 Protein (HMG1)IBA
01/2018 - 01/2010
10AntigensIBA
09/2023 - 02/2006
10Cisplatin (Platino)FDA LinkGeneric
12/2022 - 02/2014
9Reactive Oxygen Species (Oxygen Radicals)IBA
05/2024 - 06/2010
9CytokinesIBA
03/2024 - 06/2012
9Messenger RNA (mRNA)IBA
09/2023 - 06/2008
8Indicators and Reagents (Reagents)IBA
12/2023 - 01/2015
8CateninsIBA
10/2021 - 02/2016
7Circular RNAIBA
01/2024 - 10/2018
7Immune Checkpoint InhibitorsIBA
11/2023 - 01/2020
7MatrinesIBA
12/2020 - 01/2016
6mRNA VaccinesIBA
04/2024 - 01/2020
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2024 - 01/2013
6Docetaxel (Taxotere)FDA Link
03/2024 - 10/2014
6Analgesics (Analgesic Drugs)IBA
12/2023 - 10/2012
6Antiviral Agents (Antivirals)IBA
11/2022 - 11/2002
6Interleukin-6 (Interleukin 6)IBA
08/2022 - 06/2014
6Long Noncoding RNAIBA
01/2022 - 02/2016
5Androgen Receptors (Androgen Receptor)IBA
05/2024 - 09/2019
5Methionine EnkephalinIBA
12/2023 - 07/2021
5ChromatinIBA
01/2023 - 05/2014
5MicroRNAs (MicroRNA)IBA
01/2023 - 07/2012
5Phosphotransferases (Kinase)IBA
11/2022 - 01/2019
5RNA (Ribonucleic Acid)IBA
09/2022 - 06/2014
4enzalutamideIBA
05/2024 - 01/2018
4Deoxyribonuclease I (Nickase)IBA
01/2024 - 08/2015
4EnzymesIBA
09/2023 - 01/2010
4LipidsIBA
01/2023 - 07/2015
4LigandsIBA
01/2023 - 11/2006
4myricetinIBA
10/2022 - 01/2018
4ProdrugsIBA
09/2022 - 11/2019
4Liposomes (Liposome)IBA
10/2021 - 01/2020
4sharpinIBA
07/2021 - 10/2014
4Arsenic Trioxide (Trisenox)FDA Link
08/2020 - 01/2014
4p38 Mitogen-Activated Protein KinasesIBA
02/2020 - 08/2006
4Histones (Histone)IBA
01/2020 - 09/2011
3AlbuminsIBA
05/2024 - 12/2016
3PolymersIBA
05/2024 - 08/2017
3Tyrosine Kinase InhibitorsIBA
02/2024 - 11/2019
3G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
02/2024 - 04/2015
3Arginine (L-Arginine)FDA Link
01/2024 - 10/2018

Therapy/Procedure

59Therapeutics
05/2024 - 04/2007
25Drug Therapy (Chemotherapy)
05/2024 - 06/2012
18Castration
03/2024 - 01/2016
11Immunotherapy
11/2023 - 01/2020
8Radiotherapy
03/2024 - 03/2014
7Electroacupuncture
12/2023 - 01/2019
6Adjuvant Chemotherapy
12/2023 - 01/2017
6Cystectomy
01/2023 - 05/2008
5Length of Stay
09/2023 - 10/2012
5Oral Administration
01/2023 - 09/2012
5Nephrectomy
04/2016 - 10/2012
4Aftercare (After-Treatment)
10/2023 - 11/2005
4Ligation
01/2021 - 09/2011
4Liver Transplantation
12/2020 - 03/2018