Wenwei Hu Selected Research

trametinib

1/2023

Inhibition of autophagy and MEK promotes ferroptosis in Lkb1-deficient Kras-driven lung tumors.

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Wenwei Hu Research Topics

Disease

72	Neoplasms (Cancer) 03/2024 - 03/2002
22	Carcinogenesis 01/2022 - 03/2002
11	Neoplasm Metastasis (Metastasis) 01/2024 - 01/2011
8	Colorectal Neoplasms (Colorectal Cancer) 05/2024 - 10/2014
8	Breast Neoplasms (Breast Cancer) 03/2024 - 11/2009
7	Lung Neoplasms (Lung Cancer) 01/2023 - 04/2003
5	Hypoxia (Hypoxemia) 05/2024 - 07/2014
5	Colonic Neoplasms (Colon Cancer) 07/2023 - 01/2019
4	Hepatocellular Carcinoma (Hepatoma) 12/2017 - 11/2002
4	Stomach Neoplasms (Stomach Cancer) 08/2017 - 03/2016
3	Inflammation (Inflammations) 01/2024 - 01/2011
3	Parkinson Disease (Parkinson's Disease) 01/2020 - 11/2017
3	Urinary Bladder Neoplasms (Bladder Cancer) 09/2011 - 05/2002
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2023 - 12/2022
2	Myeloid Leukemia (Leukemia, Myelocytic) 01/2023 - 01/2021
2	Leukemia 11/2022 - 01/2015
2	Infections 01/2021 - 01/2018
2	Triple Negative Breast Neoplasms 01/2017 - 11/2014
2	Ataxia Telangiectasia (Louis Bar Syndrome) 10/2007 - 10/2005
1	Cachexia 01/2024
1	Adenocarcinoma 01/2023
1	Graft vs Host Disease (Graft-Versus-Host Disease) 11/2022
1	Hematologic Neoplasms (Hematological Malignancy) 11/2022
1	Carcinoma (Carcinomatosis) 11/2022
1	Appendiceal Neoplasms (Appendix Cancer) 06/2022
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2022
1	Intestinal Obstruction (Obstruction, Intestinal) 01/2022
1	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 01/2022

Drug/Important Bio-Agent (IBA)

32	Proteins (Proteins, Gene)FDA Link 01/2024 - 04/2007
10	Codon (Codons)IBA 01/2018 - 05/2002
7	Leukemia Inhibitory FactorIBA 01/2024 - 07/2011
7	DNA (Deoxyribonucleic Acid)IBA 05/2017 - 05/2002
6	Biomarkers (Surrogate Marker)IBA 03/2024 - 02/2014
6	Small Interfering RNA (siRNA)IBA 01/2022 - 07/2014
6	MicroRNAs (MicroRNA)IBA 01/2019 - 06/2010
5	CytokinesIBA 01/2024 - 01/2015
5	DNA AdductsIBA 09/2011 - 10/2002
4	EnzymesIBA 05/2024 - 09/2016
4	UbiquitinIBA 01/2023 - 01/2016
4	Messenger RNA (mRNA)IBA 12/2022 - 02/2014
4	CarcinogensIBA 09/2011 - 04/2003
4	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 10/2006 - 03/2002
3	ErbB Receptors (EGF Receptor)IBA 05/2024 - 05/2017
3	Long Noncoding RNAIBA 01/2023 - 01/2019
3	Ligases (Synthetase)IBA 01/2023 - 01/2016
3	Monomeric GTP-Binding ProteinsIBA 12/2022 - 01/2016
3	RNA (Ribonucleic Acid)IBA 12/2022 - 01/2019
3	Transcription Factors (Transcription Factor)IBA 07/2021 - 01/2015
3	Circular RNAIBA 02/2021 - 01/2019
3	AntioxidantsIBA 11/2020 - 04/2010
3	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2020 - 11/2017
3	SmokeIBA 10/2006 - 04/2003
2	Cetuximab (Erbitux)FDA Link 05/2024 - 12/2022
2	Lactate Dehydrogenase 5IBA 05/2024 - 12/2022
2	AntigensIBA 03/2024 - 12/2022
2	ChromatinIBA 01/2024 - 01/2017
2	Peptides (Polypeptides)IBA 01/2024 - 01/2019
2	LipidsIBA 01/2024 - 09/2016
2	CytosineIBA 09/2023 - 05/2002
2	A-factor (Streptomyces)IBA 01/2023 - 01/2021
2	Indicators and Reagents (Reagents)IBA 06/2022 - 02/2014
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 04/2007
2	Hormones (Hormone)IBA 01/2021 - 11/2014
2	Interleukin-33IBA 07/2017 - 05/2017
2	GlutaminaseIBA 01/2016 - 05/2014
2	chromium hexavalent ionIBA 11/2004 - 04/2003
2	Benzo(a)pyreneIBA 03/2004 - 10/2002
2	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxideIBA 03/2004 - 04/2003
2	4-biphenylamineIBA 10/2002 - 05/2002
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 05/2024
1	PeriostinIBA 03/2024
1	Carcinoembryonic AntigenIBA 03/2024
1	IsotopesIBA 01/2024
1	Mutant Proteins (Protein, Mutant)IBA 01/2024
1	Fenofibrate (CiL)FDA LinkGeneric 01/2024
1	Neutralizing AntibodiesIBA 01/2024
1	Fluorouracil (Carac)FDA LinkGeneric 07/2023
1	human ERBB2 proteinIBA 01/2023
1	trametinibIBA 01/2023
1	NivolumabIBA 01/2023
1	Adenosine Triphosphate (ATP)IBA 01/2023
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2023
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2023
1	AcetyltransferasesIBA 12/2022
1	GTP Phosphohydrolases (GTPases)IBA 12/2022
1	sintilimabIBA 12/2022
1	GTPase-Activating Proteins (GTPase-Activating Protein)IBA 12/2022
1	Docetaxel (Taxotere)FDA Link 12/2022
1	Mannose ReceptorIBA 11/2022
1	Small Cytoplasmic RNAIBA 11/2022
1	Monoclonal AntibodiesIBA 01/2022
1	Epithelial Cell Adhesion MoleculeIBA 01/2022

Therapy/Procedure

21	Therapeutics 05/2024 - 01/2011
7	Drug Therapy (Chemotherapy) 03/2024 - 11/2014
2	Ligation 01/2024 - 10/2006
2	Immunotherapy 08/2017 - 11/2015
1	Cardiopulmonary Resuscitation (CPR) 01/2024
1	Radiotherapy 01/2023
1	Hematopoietic Stem Cell Transplantation 11/2022
1	Adjuvant Chemotherapy 01/2022