James F Howard Selected Research

Interferons

1/2022

Pathogenic TNF-α drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity.

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James F Howard Research Topics

Disease

50	Myasthenia Gravis 02/2024 - 11/2009
6	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2022 - 12/2011
5	Autoimmune Diseases (Autoimmune Disease) 01/2024 - 04/2015
4	Muscle Weakness 01/2024 - 01/2018
4	Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 06/2022 - 11/2009
4	Muscular Dystrophies (Muscular Dystrophy) 09/2015 - 08/2010
3	Fatigue 02/2024 - 08/2019
3	Body Weight (Weight, Body) 08/2023 - 01/2023
3	Polyneuropathies (Polyneuropathy) 06/2022 - 10/2018
2	Meningococcal Infections 08/2023 - 01/2019
2	Respiratory Tract Infections (Respiratory Tract Infection) 01/2022 - 12/2017
2	Thymoma (Thymic Carcinoma) 12/2017 - 05/2017
2	Muscular Diseases (Myopathy) 11/2009 - 03/2003
1	Rare Diseases (Rare Disease) 10/2023
1	Clinical Deterioration 08/2023
1	COVID-19 01/2023
1	Neoplasms (Cancer) 01/2023
1	Ataxia (Dyssynergia) 06/2022
1	Cough 01/2022
1	Demyelinating Diseases (Demyelinating Disease) 01/2022
1	Scoliosis 01/2022
1	Vomiting 01/2022
1	Neuromyelitis Optica (Devic's Disease) 01/2021
1	Nervous System Diseases (Neurological Disorders) 08/2019
1	Thymus Neoplasms (Thymus Neoplasm) 12/2017
1	Meningococcal Meningitis 12/2017
1	Headache (Headaches) 12/2017
1	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy) 09/2015
1	Peripheral Nervous System Diseases (PNS Diseases) 04/2013
1	Autoimmune Polyendocrinopathies (Schmidt Syndrome) 04/2013
1	Contracture 02/2012
1	Pain (Aches) 02/2012
1	Pseudotumor Cerebri (Idiopathic Intracranial Hypertension) 12/2011
1	Obesity 12/2011
1	Morbid Obesity 12/2011

Drug/Important Bio-Agent (IBA)

21	Cholinergic ReceptorsIBA 02/2024 - 07/2013
16	glucose-mannose-glucoseIBA 02/2024 - 01/2018
14	eculizumab FDA Link 10/2021 - 07/2013
11	AutoantibodiesIBA 01/2024 - 11/2016
6	ravulizumabIBA 02/2024 - 05/2022
6	Complement Inactivating AgentsIBA 10/2023 - 12/2017
5	zilucoplanIBA 02/2024 - 01/2020
4	Complement System Proteins (Complement)IBA 01/2023 - 12/2017
4	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 03/2003
4	Phosphotransferases (Kinase)IBA 09/2021 - 04/2015
4	DystrophinIBA 02/2012 - 08/2010
3	muskIBA 09/2021 - 01/2019
3	Intravenous Immunoglobulins (IVIG)FDA Link 01/2020 - 11/2009
3	Rituximab (Mabthera)FDA Link 01/2019 - 09/2017
3	CytokinesIBA 01/2019 - 04/2013
2	Immunoglobulin G (IgG)IBA 01/2024 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 01/2023 - 02/2012
2	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 04/2015
2	deflazacortIBA 01/2022 - 12/2011
2	Prednisone (Sone)FDA LinkGeneric 01/2022 - 12/2011
2	Complement C5 (Complement 5)IBA 10/2021 - 05/2021
2	Immunoglobulin Fc FragmentsIBA 01/2021 - 01/2019
2	Proteins (Proteins, Gene)FDA Link 01/2019 - 10/2018
2	Immunoglobulins (Immunoglobulin)IBA 01/2019 - 11/2016
2	SteroidsIBA 05/2018 - 07/2016
2	AntibodiesIBA 05/2017 - 11/2016
2	Saline SolutionIBA 09/2015 - 02/2012
1	Chimeric Antigen ReceptorsIBA 01/2023
1	B-Cell Maturation AntigenIBA 01/2023
1	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 01/2023
1	RNA (Ribonucleic Acid)IBA 01/2023
1	Immune Checkpoint InhibitorsIBA 01/2023
1	bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA 01/2023
1	Monoclonal AntibodiesIBA 06/2022
1	Riboflavin (Vitamin B2)FDA LinkGeneric 06/2022
1	Investigational DrugsIBA 06/2022
1	Acetylcholine (Acetylcholine Chloride)FDA Link 05/2022
1	GlucocorticoidsIBA 01/2022
1	InterferonsIBA 01/2022
1	LigandsIBA 01/2022
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022
1	AgrinIBA 01/2020
1	Interleukin-17 (Interleukin 17)IBA 01/2020
1	2-methylcyclopentadienyl manganese tricarbonyl (MMT)IBA 10/2019
1	Tacrolimus (Prograf)FDA LinkGeneric 01/2019
1	neonatal Fc receptorIBA 01/2019
1	Circulating MicroRNAIBA 12/2018
1	PeriostinIBA 10/2018
1	Interleukin-10 (Interleukin 10)IBA 01/2018
1	Dihydrotachysterol (AT 10)IBA 09/2017
1	Immunosuppressive Agents (Immunosuppressants)IBA 09/2017
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 05/2017
1	VaccinesIBA 11/2016
1	Methotrexate (Mexate)FDA LinkGeneric 07/2016
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 04/2015
1	Immunomodulating AgentsIBA 04/2015

Therapy/Procedure

19	Activities of Daily Living (ADL) 02/2024 - 07/2016
8	Therapeutics 01/2023 - 02/2012
3	Plasma Exchange 10/2019 - 11/2016
2	Thymectomy 01/2019 - 12/2017
2	Analgesia 09/2015 - 02/2012
1	Denervation 06/2022
1	Continuous Positive Airway Pressure 01/2022
1	Anesthesia 02/2012
1	Punctures 02/2012