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Kiyohiro Houkin Selected Research

Therapeutic Uses

11/2020Neuroprotective effects of combination therapy of regional cold perfusion and hemoglobin-based oxygen carrier administration on rat transient cerebral ischemia.
10/2020Clinical Trials of Stem Cell Therapy for Cerebral Ischemic Stroke.
5/2018[18F]DPA-714 PET imaging shows immunomodulatory effect of intravenous administration of bone marrow stromal cells after transient focal ischemia.
7/2016Transarterial Regional Brain Hypothermia Inhibits Acute Aquaporin-4 Surge and Sequential Microvascular Events in Ischemia/Reperfusion Injury.
1/2015Therapeutic effects of human multilineage-differentiating stress enduring (MUSE) cell transplantation into infarct brain of mice.
4/2013Timing and cell dose determine therapeutic effects of bone marrow stromal cell transplantation in rat model of cerebral infarct.
4/2012Impact of ageing on biological features of bone marrow stromal cells (BMSC) in cell transplantation therapy for CNS disorders: functional enhancement by granulocyte-colony stimulating factor (G-CSF).
2/2012Therapeutic effects of intra-arterial delivery of bone marrow stromal cells in traumatic brain injury of rats--in vivo cell tracking study by near-infrared fluorescence imaging.
1/2010Therapeutic benefits of human mesenchymal stem cells derived from bone marrow after global cerebral ischemia.

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Kiyohiro Houkin Research Topics

Disease

39Stroke (Strokes)
03/2024 - 10/2002
31Neoplasms (Cancer)
01/2021 - 01/2003
30Ischemic Stroke
03/2024 - 05/2012
19Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
11/2020 - 02/2004
18Infarction (Infarctions)
03/2024 - 02/2004
18Moyamoya Disease (Moya-Moya Disease)
02/2021 - 12/2004
14Aneurysm (Aneurysms)
06/2022 - 10/2002
14Glioma (Gliomas)
12/2020 - 08/2003
14Ischemia
11/2020 - 01/2003
12Hemorrhage
01/2023 - 09/2005
12Glioblastoma (Glioblastoma Multiforme)
04/2021 - 08/2003
12Brain Ischemia (Cerebral Ischemia)
01/2021 - 02/2004
11Cerebral Infarction
01/2019 - 02/2007
8Intracranial Aneurysm (Cerebral Aneurysm)
06/2022 - 01/2011
7Inflammation (Inflammations)
01/2022 - 10/2014
7Brain Infarction
01/2017 - 09/2011
6Brain Neoplasms (Brain Tumor)
01/2019 - 06/2004
6Thrombosis (Thrombus)
07/2015 - 06/2007
5Spinal Cord Injuries (Spinal Cord Injury)
01/2022 - 11/2009
5Pathologic Constriction (Stenosis)
10/2021 - 01/2005
5Cysts
01/2018 - 03/2014
5Infections
05/2012 - 01/2005
4Hematoma
12/2016 - 09/2005
4Carotid Stenosis (Carotid Artery Stenosis)
08/2015 - 02/2005
3Lacunar Stroke
01/2023 - 01/2013
3Hypertension (High Blood Pressure)
06/2022 - 06/2012
3Pain (Aches)
01/2021 - 01/2017
3Central Nervous System Diseases (CNS Diseases)
01/2021 - 12/2006
3Reperfusion Injury
11/2020 - 03/2014
3Brain Edema (Cerebral Edema)
11/2020 - 11/2009
3Carcinogenesis
01/2020 - 01/2003
3Brain Injuries (Brain Injury)
01/2020 - 03/2015
3Headache (Headaches)
04/2019 - 11/2013
3Hypoxia (Hypoxemia)
01/2018 - 05/2012
3Edema (Dropsy)
12/2016 - 11/2009
3Necrosis
12/2016 - 05/2012
3Hemifacial Spasm
10/2016 - 11/2011
3Arteriovenous Malformations (Arteriovenous Malformation)
01/2014 - 11/2004
3Intracranial Arteriovenous Malformations (Cerebral Arteriovenous Malformation)
07/2012 - 11/2004
3Traumatic Brain Injuries (Traumatic Brain Injury)
04/2012 - 11/2009
2Transient Ischemic Attack
12/2021 - 11/2020
2Parkinson Disease (Parkinson's Disease)
09/2021 - 01/2021
2Neuralgia (Stump Neuralgia)
01/2021 - 01/2020

Drug/Important Bio-Agent (IBA)

11Proteins (Proteins, Gene)FDA Link
11/2020 - 08/2003
9Therapeutic UsesIBA
11/2020 - 01/2010
6Cilostazol (Pletal)FDA LinkGeneric
01/2023 - 03/2015
6Oxygen (Dioxygen)IBA
11/2020 - 12/2003
5CytokinesIBA
01/2022 - 02/2004
5Tissue Plasminogen Activator (Alteplase)FDA Link
12/2021 - 01/2012
5Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
11/2021 - 07/2011
5Neuroprotective AgentsIBA
11/2020 - 03/2015
4Clopidogrel (Plavix)FDA Link
11/2021 - 12/2018
4Bevacizumab (Avastin)FDA Link
04/2021 - 01/2016
4Coloring Agents (Dyes)IBA
12/2020 - 10/2011
4Temozolomide (Temodar)FDA LinkGeneric
12/2020 - 02/2012
4fluoromisonidazoleIBA
01/2016 - 02/2012
4DNA (Deoxyribonucleic Acid)IBA
01/2016 - 08/2003
4GadoliniumIBA
01/2016 - 08/2010
3ferric oxide (iron oxide)IBA
03/2024 - 09/2011
32'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
01/2023 - 10/2021
3Hemoglobins (Hemoglobin)IBA
11/2020 - 11/2005
3Fingolimod Hydrochloride (FTY720)FDA Link
10/2020 - 01/2020
3AcidsIBA
06/2019 - 09/2015
3Indocyanine Green (Cardio-Green)FDA LinkGeneric
01/2018 - 03/2011
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2016 - 03/2009
3Eosine Yellowish-(YS) (Eosin)IBA
05/2014 - 10/2011
3Hematoxylin (Haematoxylon)IBA
05/2014 - 10/2011
3Acetazolamide (Diamox)FDA LinkGeneric
11/2013 - 12/2003
3Brain-Derived Neurotrophic Factor (BDNF)IBA
11/2009 - 02/2004
3Protons (Proton)IBA
02/2007 - 06/2004
2Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
02/2022 - 01/2013
2Contrast MediaIBA
10/2021 - 10/2005
2Indicators and Reagents (Reagents)IBA
02/2021 - 11/2013
2Serotonin (5 Hydroxytryptamine)IBA
01/2021 - 01/2020

Therapy/Procedure

40Therapeutics
03/2024 - 02/2005
22Transplantation
03/2024 - 12/2006
15Radiotherapy
12/2020 - 10/2002
12Cell- and Tissue-Based Therapy (Cell Therapy)
01/2024 - 01/2005
11Drug Therapy (Chemotherapy)
12/2020 - 08/2003
8Intravenous Administration
01/2024 - 05/2004
8Thrombectomy
10/2021 - 08/2017
7Operative Surgical Procedures
01/2021 - 10/2002
5Craniotomy
11/2016 - 05/2004
5Carotid Endarterectomy
08/2015 - 01/2005
4Ligation
11/2016 - 01/2005
4Stents
01/2016 - 02/2005
3Secondary Prevention
01/2023 - 06/2013
3Surgical Instruments (Clip)
04/2020 - 01/2013
3Aftercare (After-Treatment)
01/2019 - 08/2012
3Ventriculoperitoneal Shunt
11/2018 - 11/2011
3Punctures
10/2018 - 01/2016
3Microvascular Decompression Surgery
10/2016 - 11/2011
3Cell Transplantation
06/2015 - 09/2011
3Decompression
01/2012 - 04/2005
2Combined Modality Therapy
02/2022 - 02/2012
2Deep Brain Stimulation
09/2021 - 01/2021
2Cannula
01/2021 - 01/2020
2Injections
01/2021 - 01/2010
2Stem Cell Transplantation
01/2021 - 01/2020
2Chemoradiotherapy
01/2021 - 09/2015