Emily Ho Selected Research

Histone Deacetylases (Histone Deacetylase)

3/2018	Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice.
1/2016	HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells.
12/2015	Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy.
9/2012	3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.
7/2011	Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells.
6/2011	Metabolism as a key to histone deacetylase inhibition.
5/2011	Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly.
12/2009	Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention.
4/2009	Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.
10/2007	Dietary histone deacetylase inhibitors: from cells to mice to man.

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Emily Ho Research Topics

Disease

50	Neoplasms (Cancer) 02/2023 - 12/2002
26	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 08/2004
13	Inflammation (Inflammations) 01/2022 - 08/2004
13	Colonic Neoplasms (Colon Cancer) 01/2019 - 03/2006
11	Carcinogenesis 11/2023 - 03/2006
7	Chronic Disease (Chronic Diseases) 12/2023 - 10/2007
7	Breast Neoplasms (Breast Cancer) 02/2023 - 04/2008
5	Hyperplasia 05/2011 - 04/2006
4	Body Weight (Weight, Body) 08/2023 - 08/2007
3	Genomic Instability 01/2024 - 12/2009
3	Cognitive Dysfunction 01/2023 - 01/2011
3	Dementia (Dementias) 01/2023 - 01/2011
3	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 10/2016
3	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2018 - 12/2015
2	Infections 10/2022 - 07/2009
2	Lymphoma (Lymphomas) 09/2020 - 08/2010
2	Ductal Carcinoma 01/2018 - 05/2016
2	Breast Ductal Carcinoma 05/2016 - 12/2015
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 07/2013 - 01/2012
2	Cardiovascular Diseases (Cardiovascular Disease) 08/2012 - 10/2007
1	Malnutrition (Nutritional Deficiencies) 12/2023
1	Neural Tube Defects (Exencephaly) 12/2023
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2023
1	Weight Gain 08/2023
1	Weight Loss (Weight Reduction) 10/2022
1	Morbid Obesity 10/2022
1	Mouth Neoplasms (Oral Cancer) 04/2022
1	Cleft Lip (Harelip) 02/2022
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	COVID-19 01/2021
1	Esophagitis 12/2020
1	Gastroesophageal Reflux (GERD) 12/2020
1	Constrictive Pericarditis 02/2020
1	Diabetes Mellitus 12/2019
1	Insulinoma 12/2019

Drug/Important Bio-Agent (IBA)

27	sulforaphaneIBA 04/2022 - 03/2006
20	ZincIBA 01/2022 - 12/2002
15	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2002
14	Histone Deacetylases (Histone Deacetylase)IBA 03/2018 - 03/2006
13	PhytochemicalsIBA 01/2021 - 12/2009
12	Histones (Histone)IBA 01/2022 - 03/2006
10	DNA (Deoxyribonucleic Acid)IBA 01/2024 - 12/2002
9	Histone Deacetylase InhibitorsIBA 01/2016 - 02/2006
8	Biomarkers (Surrogate Marker)IBA 01/2023 - 04/2009
7	CarcinogensIBA 01/2017 - 10/2008
6	MicroRNAs (MicroRNA)IBA 01/2022 - 11/2011
6	3,3'-diindolylmethane (diindolylmethane)IBA 01/2021 - 01/2012
5	isothiocyanic acidIBA 04/2022 - 04/2006
5	Messenger RNA (mRNA)IBA 01/2022 - 09/2012
5	indole-3-carbinolIBA 01/2021 - 01/2012
5	ChromatinIBA 01/2017 - 01/2016
5	AndrogensIBA 10/2014 - 04/2006
4	RNA (Ribonucleic Acid)IBA 01/2020 - 10/2014
3	MicronutrientsIBA 12/2023 - 01/2022
3	ArsenicIBA 11/2023 - 01/2017
3	IsothiocyanatesIBA 08/2021 - 06/2013
3	EnzymesIBA 03/2018 - 02/2007
3	2- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA 10/2017 - 08/2012
3	benzocycloheptapyridineIBA 10/2017 - 08/2012
3	dibenzo(a,l)pyreneIBA 01/2017 - 01/2012
3	Transcription Factors (Transcription Factor)IBA 01/2017 - 12/2002
3	TeaIBA 05/2011 - 10/2009
2	AnionsIBA 02/2023 - 01/2023
2	Cysteine (L-Cysteine)FDA Link 02/2023 - 01/2023
2	glucoraphaninIBA 04/2022 - 10/2013
2	MethyltransferasesIBA 01/2022 - 01/2014
2	GlucosinolatesIBA 08/2021 - 01/2021
2	ProteomeIBA 09/2020 - 12/2015
2	Hormones (Hormone)IBA 12/2019 - 05/2011
2	Co-Repressor ProteinsIBA 03/2018 - 05/2011
2	AminesIBA 01/2017 - 08/2012
2	Dihydrotachysterol (AT 10)IBA 01/2017 - 07/2013
2	Lysine (L-Lysine)FDA Link 02/2016 - 01/2016
2	NF-kappa B (NF-kB)IBA 05/2011 - 06/2010
2	LigandsIBA 06/2006 - 02/2006
1	NAD (NADH)IBA 12/2023
1	XanthophyllsIBA 12/2023
1	Choline (Choline Chloride)IBA 12/2023
1	OsteocalcinIBA 08/2023
1	AlkaloidsIBA 02/2023
1	dankastatin BIBA 02/2023
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 10/2022
1	ElementsIBA 02/2022
1	iberin (IMSP)IBA 08/2021
1	Tobacco Smoke Pollution (Passive Smoking)IBA 01/2021
1	NitrilesIBA 01/2021
1	IndolesIBA 01/2021
1	SolutionsIBA 12/2020
1	Insulin (Novolin)FDA Link 12/2019
1	Blood Glucose (Blood Sugar)IBA 12/2019
1	(+)-JQ1 compoundIBA 01/2019
1	CarbohydratesIBA 01/2019

Therapy/Procedure

15	Chemoprevention 03/2018 - 08/2004
9	Therapeutics 12/2023 - 10/2007
4	Drug Therapy (Chemotherapy) 10/2022 - 04/2006
1	Bariatric Surgery 10/2022
1	Personal Protective Equipment 01/2021
1	Gastrectomy 12/2020
1	Reoperation 12/2020
1	Gastric Bypass (Roux-en-Y Gastric Bypass) 12/2020