Jonathan M G Higgins Selected Research

Neoplasms (Cancer)

1/2022	PCTAIRE1 promotes mitotic progression and resistance against antimitotic and apoptotic signals.
1/2022	Dissecting the roles of Haspin and VRK1 in histone H3 phosphorylation during mitosis.
10/2020	Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability.
1/2020	Priming chromatin for segregation: functional roles of mitotic histone modifications.
3/2012	Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors.
6/2010	Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors.
4/2010	Haspin: a newly discovered regulator of mitotic chromosome behavior.

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Jonathan M G Higgins Research Topics

Disease

7	Neoplasms (Cancer) 01/2022 - 04/2010
1	Neuromuscular Diseases (Neuromuscular Disease) 01/2022
1	Genomic Instability 10/2020
1	Aneuploidy (Aneuploid) 11/2019
1	Rheumatoid Arthritis 12/2004

Drug/Important Bio-Agent (IBA)

2	ChromatinIBA 10/2020 - 01/2020
2	Histones (Histone)IBA 01/2020 - 03/2012
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 03/2012 - 06/2010
1	Antimitotic AgentsIBA 01/2022
1	Protamine KinaseIBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 10/2020
1	Adenosine Triphosphate (ATP)IBA 10/2020
1	Cyclin B1IBA 11/2019
1	Phosphotransferases (Kinase)IBA 04/2010
1	osteoblast cadherinIBA 12/2004

Therapy/Procedure

1	Therapeutics 04/2010