Timothy E Hewett Selected Research

Calcineurin

1/2004	Calcineurin Abeta gene targeting predisposes the myocardium to acute ischemia-induced apoptosis and dysfunction.
5/2003	Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling.

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Timothy E Hewett Research Topics

Disease

20	Anterior Cruciate Ligament Injuries 09/2022 - 10/2003
11	Wounds and Injuries (Trauma) 10/2021 - 10/2009
6	Pain (Aches) 07/2023 - 02/2005
5	Knee Injuries (Knee Injury) 07/2023 - 01/2014
4	Heart Failure 09/2007 - 03/2004
3	Osteoarthritis 07/2023 - 01/2019
3	Reinjuries 01/2019 - 10/2010
3	Hypertrophy 02/2006 - 06/2002
2	Inflammation (Inflammations) 04/2023 - 02/2014
2	Sprains and Strains (Sprain) 10/2009 - 10/2009
2	Cardiomyopathies (Cardiomyopathy) 09/2007 - 08/2006
2	Knee Osteoarthritis 02/2007 - 02/2005
2	Ischemia 09/2005 - 01/2004
2	Cardiomegaly (Heart Hypertrophy) 05/2004 - 05/2003
1	Postoperative Pain 07/2023
1	Contusions 02/2023
1	Fatigue 05/2021
1	Arthritis (Polyarthritis) 04/2018
1	Foot Injuries (Foot Injury) 01/2018
1	Rupture 01/2018
1	Paresis (Hemiparesis) 01/2017
1	Stroke (Strokes) 01/2017
1	Necrosis 09/2007
1	Congenital Abnormalities (Deformity) 02/2005
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 03/2004
1	Reperfusion Injury 01/2004
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 05/2003

Drug/Important Bio-Agent (IBA)

4	insulin receptor-related receptor (IRR)IBA 08/2018 - 07/2014
3	cysteine and glycine-rich protein 3IBA 08/2006 - 03/2004
2	Proteins (Proteins, Gene)FDA Link 02/2014 - 02/2006
2	ElementsIBA 01/2014 - 08/2011
2	Isoproterenol (Isoprenaline)FDA LinkGeneric 09/2007 - 05/2003
2	CalcineurinIBA 01/2004 - 05/2003
2	LuciferasesIBA 01/2004 - 05/2003
1	Morphine (MS Contin)FDA LinkGeneric 07/2023
1	pyrenylmethyl tributylphosphoniumIBA 02/2023
1	Pyridinolcarbamate (P23)IBA 09/2022
1	methyl methanethiosulfonate (MMTS)IBA 10/2021
1	A-factor (Streptomyces)IBA 05/2021
1	OF 743IBA 08/2020
1	A 7 (A-7)IBA 01/2020
1	P 11 (P-11)IBA 01/2019
1	Dihydrotachysterol (AT 10)IBA 04/2018
1	salicylhydroxamic acid (SHAM)IBA 01/2018
1	N 30IBA 01/2017
1	ORALIT (ORS)IBA 04/2014
1	Smad Proteins (Mothers Against Decapentaplegic Homolog)IBA 02/2014
1	NF-kappa B (NF-kB)IBA 02/2014
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 02/2014
1	Indicators and Reagents (Reagents)IBA 02/2014
1	Silicon Dioxide (Silica)FDA LinkGeneric 06/2011
1	beta Adrenergic ReceptorsIBA 09/2007
1	Cyclophilins (Cyclophilin)IBA 09/2007
1	Mitochondrial Permeability Transition PoreIBA 09/2007
1	Oral ContraceptivesIBA 04/2007
1	Ro 31-8220IBA 08/2006
1	Ro 32-0432IBA 08/2006
1	Protein Kinases (Protein Kinase)IBA 08/2006
1	Protein Isoforms (Isoforms)IBA 08/2006
1	Complementary DNA (cDNA)IBA 08/2006
1	Inhibitory Smad ProteinsIBA 02/2006
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2006
1	Phosphotransferases (Kinase)IBA 09/2005
1	rho Guanine Nucleotide Dissociation Inhibitor alphaIBA 05/2004
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 05/2004
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 01/2004
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 01/2004
1	CalciumIBA 01/2004
1	DNA (Deoxyribonucleic Acid)IBA 01/2004
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 05/2003
1	p38 Mitogen-Activated Protein KinasesIBA 05/2003
1	Ventricular MyosinsIBA 06/2002
1	Atrial Natriuretic Factor (ANF)IBA 06/2002

Therapy/Procedure

7	Anterior Cruciate Ligament Reconstruction 09/2022 - 07/2007
4	Activities of Daily Living (ADL) 09/2022 - 11/2015
3	Therapeutics 04/2023 - 05/2017
2	Braces 01/2017 - 02/2005
2	Psychology Biofeedback (Biofeedback) 02/2016 - 01/2015
2	Resistance Training 10/2009 - 10/2009
1	Meniscectomy 07/2023
1	Contraindications 04/2023
1	Preoperative Exercise 01/2020
1	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2019
1	Arthroplasty 01/2019
1	Secondary Prevention 03/2012
1	Surgical Instruments (Clip) 09/2009
1	Viscosupplementation 02/2007
1	Replacement Arthroplasty 02/2005
1	Transcutaneous Electric Nerve Stimulation (TENS) 10/2003