Heike Heuer Selected Research

Thyroid Hormones

2/2023	Triac Treatment Prevents Neurodevelopmental and Locomotor Impairments in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice.
12/2022	TRIAC Treatment Improves Impaired Brain Network Function and White Matter Loss in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice.
1/2022	AAV9-MCT8 Delivery at Juvenile Stage Ameliorates Neurological and Behavioral Deficits in a Mouse Model of MCT8-Deficiency.
1/2022	Distinct Actions of the Thyroid Hormone Transporters Mct8 and Oatp1c1 in Murine Adult Hippocampal Neurogenesis.
1/2021	Oligodendrocyte progenitor cell maturation is dependent on dual function of MCT8 in the transport of thyroid hormone across brain barriers and the plasma membrane.
1/2020	Central Hypothyroidism Impairs Heart Rate Stability and Prevents Thyroid Hormone-Induced Cardiac Hypertrophy and Pyrexia.
1/2018	Deafness and loss of cochlear hair cells in the absence of thyroid hormone transporters Slc16a2 (Mct8) and Slc16a10 (Mct10).
5/2014	Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis.
3/2012	Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain.
2/2010	Consequences of monocarboxylate transporter 8 deficiency for renal transport and metabolism of thyroid hormones in mice.

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Heike Heuer Research Topics

Disease

9	Hypothyroidism 10/2022 - 03/2012
7	Allan-Herndon-Dudley syndrome 12/2022 - 02/2010
4	Body Weight (Weight, Body) 09/2015 - 03/2003
3	Hyperthyroidism 01/2020 - 02/2010
2	Brain Injuries (Brain Injury) 01/2021 - 03/2011
2	Cerebellar Ataxia (Dysmetria) 03/2013 - 03/2010
2	Inflammation (Inflammations) 03/2011 - 10/2007
1	Intellectual Disability (Idiocy) 02/2023
1	Nervous System Diseases (Neurological Disorders) 01/2022
1	Hyperoxia 01/2021
1	Lung Diseases (Lung Disease) 01/2021
1	Fever (Fevers) 01/2020
1	Bacterial Infections (Bacterial Infection) 01/2020
1	Tachycardia (Tachyarrhythmias) 01/2020
1	Infections 01/2020
1	Cardiomegaly (Heart Hypertrophy) 01/2020
1	Deafness (Deaf Mutism) 01/2018
1	Seminoma 11/2016
1	Hepatocellular Carcinoma (Hepatoma) 12/2015
1	Starvation 02/2015
1	Neurofibromatosis 2 (Neurofibromatosis Type II) 01/2015
1	Neurilemmoma (Schwannoma) 01/2015
1	Melanoma (Melanoma, Malignant) 03/2013
1	Seizures (Absence Seizure) 03/2013
1	Limbic Encephalitis (Paraneoplastic Limbic Encephalitis) 03/2013
1	Cerebral Infarction 03/2011
1	Pathologic Processes 12/2007
1	Hypertrophy 07/2005
1	Hyperplasia 07/2005
1	Congenital Hypothyroidism (Cretinism) 03/2004
1	Vascular Diseases (Vascular Disease) 05/2003

Drug/Important Bio-Agent (IBA)

10	Thyroid HormonesIBA 02/2023 - 02/2010
5	Iodide Peroxidase (Deiodinase)IBA 01/2021 - 03/2003
4	Messenger RNA (mRNA)IBA 01/2021 - 03/2003
3	Triiodothyronine (Liothyronine)FDA LinkGeneric 01/2022 - 01/2021
2	Thyroxine (Levothyroxine)FDA LinkGeneric 03/2021 - 01/2021
2	Interleukin-6 (Interleukin 6)IBA 01/2020 - 03/2011
2	Thyrotropin-Releasing Hormone Receptors (Thyrotropin Releasing Hormone Receptor)IBA 01/2017 - 04/2013
2	Proteins (Proteins, Gene)FDA Link 11/2016 - 12/2007
2	tetraiodothyroacetic acid (TA(4))IBA 12/2015 - 02/2013
2	CytokinesIBA 04/2013 - 03/2011
2	AntibodiesIBA 03/2013 - 03/2010
1	ParvalbuminsIBA 10/2022
1	Calcium-Binding ProteinsIBA 10/2022
1	Organic Anion TransportersIBA 01/2022
1	Peptides (Polypeptides)IBA 01/2022
1	Oxygen (Dioxygen)IBA 01/2021
1	ProteomeIBA 01/2020
1	Immunoglobulins (Immunoglobulin)IBA 01/2017
1	Conditioned Culture MediaIBA 12/2015
1	AcyltransferasesIBA 02/2015
1	GhrelinIBA 02/2015
1	Neurofibromin 2 (Merlin)IBA 01/2015
1	LeptinIBA 04/2013
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 04/2013
1	AutoantibodiesIBA 03/2013
1	gamma-Aminobutyric Acid (GABA)IBA 03/2013
1	InterferonsIBA 03/2013
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 03/2011
1	P-SelectinIBA 03/2011
1	E-SelectinIBA 03/2011
1	EndotoxinsIBA 03/2011
1	LipopolysaccharidesIBA 03/2011
1	InterleukinsIBA 03/2011
1	ChemokinesIBA 03/2011
1	Phospholipids (Phosphatides)FDA LinkGeneric 12/2007
1	AnnexinsIBA 12/2007
1	Transforming Growth Factor beta (TGF-beta)IBA 10/2007
1	Pituitary HormonesIBA 03/2004
1	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 05/2003
1	MitogensIBA 05/2003
1	Connective Tissue Growth FactorIBA 05/2003

Therapy/Procedure

1	Therapeutics 03/2013