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Leonard T Heffner Selected Research

Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)

3/2013Treatment of adults with acute lymphoblastic leukemia: do the specifics of the regimen matter?: Results from a prospective randomized trial.
2/2013High-dose vincristine sulfate liposome injection for advanced, relapsed, and refractory adult Philadelphia chromosome-negative acute lymphoblastic leukemia.
12/2009Phase 1 multicenter study of vincristine sulfate liposomes injection and dexamethasone in adults with relapsed or refractory acute lymphoblastic leukemia.

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Leonard T Heffner Research Topics

Disease

17Multiple Myeloma
11/2021 - 01/2003
6Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2021 - 04/2012
4Waldenstrom Macroglobulinemia (Macroglobulinemia)
02/2023 - 05/2017
4Neoplasms (Cancer)
02/2023 - 02/2017
4BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
05/2020 - 04/2012
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2019 - 01/2012
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
03/2013 - 12/2009
2Hodgkin Disease (Hodgkin's Disease)
01/2020 - 12/2013
2B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2019 - 09/2015
2Lymphoma (Lymphomas)
12/2013 - 12/2009
2Hematologic Neoplasms (Hematological Malignancy)
11/2013 - 08/2010
1Nausea
01/2021
1Fatigue
01/2021
1Edema (Dropsy)
01/2021
1Circulating Neoplastic Cells
01/2019
1Exanthema (Rash)
12/2017
1Bone Marrow Diseases (Bone Marrow Disease)
05/2017
1Anemia
02/2017
1Peripheral Nervous System Diseases (PNS Diseases)
11/2015
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
11/2013
1Hemorrhage
11/2013
1Philadelphia Chromosome
02/2013
1Leukemia
02/2013
1B-Cell Lymphoma (Lymphoma, B Cell)
07/2012
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
07/2012
1Venous Thrombosis (Deep-Vein Thrombosis)
08/2010
1Thrombocytopenia (Thrombopenia)
12/2005
1Residual Neoplasm
01/2003

Drug/Important Bio-Agent (IBA)

7Bortezomib (Velcade)FDA Link
12/2020 - 12/2005
6Rituximab (Mabthera)FDA Link
02/2023 - 12/2009
6Dexamethasone (Maxidex)FDA LinkGeneric
11/2021 - 12/2009
6Vincristine (Oncovin)FDA LinkGeneric
11/2015 - 12/2009
4Lenalidomide (CC 5013)FDA Link
11/2021 - 11/2019
4Tyrosine Kinase InhibitorsIBA
05/2020 - 04/2012
4Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2015 - 04/2012
3Immunoconjugates (Immunoconjugate)IBA
11/2021 - 01/2019
3venetoclaxIBA
01/2021 - 01/2019
3Doxorubicin (Adriamycin)FDA LinkGeneric
11/2015 - 04/2012
3Cytarabine (Cytosar-U)FDA LinkGeneric
12/2013 - 01/2012
2ibrutinibIBA
02/2023 - 01/2022
2indatuximab ravtansineIBA
11/2021 - 01/2019
2Immunoglobulin M (IgM)IBA
11/2021 - 05/2017
2loncastuximab tesirineIBA
01/2021 - 12/2019
2Prednisone (Sone)FDA LinkGeneric
11/2015 - 07/2012
2Liposomes (Liposome)IBA
02/2013 - 12/2009
1Immunomodulating AgentsIBA
11/2021
1pomalidomideIBA
11/2021
1EnzymesIBA
01/2021
1VorinostatFDA Link
12/2020
1Histone Deacetylase InhibitorsIBA
12/2020
1GemcitabineFDA Link
01/2020
1Bendamustine HydrochlorideFDA Link
01/2020
1pyrrolo(2,1-c)(1,4)benzodiazepineIBA
12/2019
1samalizumabIBA
01/2019
12'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
01/2019
1carfilzomibIBA
01/2019
1daratumumabIBA
01/2019
1PanobinostatIBA
01/2019
1Immune Checkpoint InhibitorsIBA
01/2019
1Therapeutic UsesIBA
01/2019
1Proteasome Endopeptidase Complex (Proteasome)IBA
01/2019
1nilotinibFDA Link
12/2017
1Dasatinib (BMS 354825)FDA Link
12/2017
1Imatinib Mesylate (Gleevec)FDA Link
12/2017
1amsonic acid (DAS)IBA
12/2017
1Hemoglobins (Hemoglobin)IBA
05/2017
1EverolimusFDA Link
05/2017
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
09/2015
1fludarabineIBA
09/2015
1ParaproteinsIBA
03/2015
1Biomarkers (Surrogate Marker)IBA
03/2015
1Etoposide (VP 16)FDA LinkGeneric
12/2013
1Cisplatin (Platino)FDA LinkGeneric
12/2013
1Vinorelbine (Navelbine)FDA LinkGeneric
12/2013
1Paclitaxel (Taxol)FDA LinkGeneric
12/2013
1Antifibrinolytic Agents (Antifibrinolytics)IBA
11/2013
1Aminocaproic Acid (6 Aminocaproic Acid)FDA LinkGeneric
11/2013
1AnthracyclinesIBA
03/2013
1Adrenal Cortex Hormones (Corticosteroids)IBA
03/2013
1Asparaginase (Elspar)FDA Link
03/2013
1Indicators and Reagents (Reagents)IBA
11/2012
1Methotrexate (Mexate)FDA LinkGeneric
04/2012
1Melphalan (Alkeran)FDA LinkGeneric
10/2010
1Thalidomide (Thalomid)FDA Link
05/2006
1Proteasome InhibitorsIBA
12/2005
1Cytotoxins (Cytolysins)IBA
12/2005
1Thrombopoietin (c-mpl Ligand)IBA
12/2005

Therapy/Procedure

11Therapeutics
12/2020 - 01/2003
4Drug Therapy (Chemotherapy)
01/2019 - 05/2006
2Salvage Therapy
01/2021 - 12/2013
2Cell Transplantation
01/2019 - 02/2013
2Transplantation
01/2019 - 05/2006
1Aftercare (After-Treatment)
05/2020
1Stem Cell Transplantation
01/2019
1Drug Tapering
12/2017
1Platelet Transfusion (Blood Platelet Transfusions)
11/2013
1Induction Chemotherapy
11/2012
1Central Venous Catheters
08/2010
1Catheters
08/2010
1Immunotherapy
01/2003