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Cheryl A Hawkes Selected Research

Alzheimer Disease (Alzheimer's Disease)

10/2023Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA), updates in 2022-2023. Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy.
1/2021Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice.
1/2020Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy.
3/2015Prenatal high-fat diet alters the cerebrovasculature and clearance of β-amyloid in adult offspring.
1/2015White matter changes in dementia: role of impaired drainage of interstitial fluid.
7/2014Failure of perivascular drainage of β-amyloid in cerebral amyloid angiopathy.
4/2014Amyloid and tau in the brain in sporadic Alzheimer's disease: defining the chicken and the egg.
1/2014The Cerebrovascular Basement Membrane: Role in the Clearance of β-amyloid and Cerebral Amyloid Angiopathy.
1/2014MK886 reduces cerebral amyloid angiopathy severity in TgCRND8 mice.
8/2013Immune complex formation impairs the elimination of solutes from the brain: implications for immunotherapy in Alzheimer's disease.
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Cheryl A Hawkes Research Topics

Disease

20Alzheimer Disease (Alzheimer's Disease)
10/2023 - 07/2006
14Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
10/2023 - 01/2009
3Cerebrovascular Disorders (Cerebrovascular Occlusion)
10/2023 - 01/2020
2Inflammation (Inflammations)
10/2023 - 01/2011
1Schizophrenia (Dementia Praecox)
01/2022
1Mental Disorders (Mental Disorder)
01/2022
1Weight Loss (Weight Reduction)
02/2020
1Obesity
02/2020
1Necrosis
02/2020
1Maternal Obesity
03/2015
1CADASIL
01/2015
1Leukoencephalopathies
01/2015
1Amyloidosis
08/2014
1Hypercapnia
08/2014
1Cognitive Dysfunction
08/2014
1Arteriosclerosis
07/2014
1Amyloid angiopathy
10/2012
1Disease Progression
10/2012
1Infections
01/2011
1Cerebral Malaria
12/2007
1Neurodegenerative Diseases (Neurodegenerative Disease)
11/2007
1Amyloid Plaque
11/2007
1Meningoencephalitis
11/2007

Drug/Important Bio-Agent (IBA)

16Amyloid (Amyloid Fibrils)IBA
10/2023 - 11/2007
7Peptides (Polypeptides)IBA
03/2015 - 08/2008
5Amyloid beta-PeptidesIBA
01/2010 - 07/2006
3Proteins (Proteins, Gene)FDA Link
01/2022 - 07/2014
2ApolipoproteinsIBA
03/2015 - 01/2015
2scyllitol (scyllo-inositol)IBA
10/2012 - 08/2008
1Retinaldehyde (Retinal)IBA
10/2023
1Dopamine (Intropin)FDA LinkGeneric
01/2022
11,2- diarachidonoyl- glycero- 3- phosphocholineIBA
01/2022
1Biomarkers (Surrogate Marker)IBA
01/2022
1Cholinergic Agents (Cholinergics)IBA
01/2021
1Interleukin-6 (Interleukin 6)IBA
02/2020
1GlucocorticoidsIBA
02/2020
1Hydrocortisone (Cortisol)FDA LinkGeneric
02/2020
1ChemokinesIBA
02/2020
1InterleukinsIBA
02/2020
1LigandsIBA
02/2020
1Fibronectins (Fibronectin)IBA
03/2015
1CollagenIBA
03/2015
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
08/2014
1Cilostazol (Pletal)FDA LinkGeneric
08/2014
1Acetylcholine (Acetylcholine Chloride)FDA Link
08/2014
1Apolipoprotein E4IBA
07/2014
1MK-886IBA
01/2014
1Antigen-Antibody Complex (Immune Complex)IBA
08/2013
1Inositol (Myoinositol)IBA
10/2012
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
01/2011
1ArtesunateIBA
01/2011
1Fingolimod Hydrochloride (FTY720)FDA Link
01/2011
1SphingolipidsIBA
01/2011
1InterferonsIBA
12/2007
1AN-1792IBA
11/2007
1Therapeutic UsesIBA
07/2006

Therapy/Procedure

4Therapeutics
10/2023 - 07/2014
4Immunotherapy
10/2023 - 11/2007