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P J Halsall Selected Research

Malignant Hyperthermia

10/2009Genetic variation in RYR1 and malignant hyperthermia phenotypes.
8/2009Epigenetic allele silencing and variable penetrance of malignant hyperthermia susceptibility.
1/2009Analysis of RYR1 haplotype profile in patients with malignant hyperthermia.
9/2006Mg2+ dependence of Ca2+ release from the sarcoplasmic reticulum induced by sevoflurane or halothane in skeletal muscle from humans susceptible to malignant hyperthermia.
11/2003Anaesthetic management of coronary artery bypass grafting in a patient with central core disease and susceptibility to malignant hyperthermia on statin therapy.
7/2003Multicentre evaluation of in vitro contracture testing with bolus administration of 4-chloro-m-cresol for diagnosis of malignant hyperthermia susceptibility.
4/2003Ryanodine receptor gene (RYR1) mutations for diagnosing susceptibility to malignant hyperthermia.

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P J Halsall Research Topics

Disease

7Malignant Hyperthermia
10/2009 - 04/2003
2Contracture
10/2009 - 07/2003
1Heat Stroke (Heatstroke)
10/2009
1Rhabdomyolysis
10/2009
1Central Core Myopathy (Central Core Disease)
11/2003
1Hypothermia
11/2003

Drug/Important Bio-Agent (IBA)

6Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
10/2009 - 04/2003
2Halothane (Fluothane)FDA Link
09/2006 - 07/2003
1Creatine Kinase (Creatine Phosphokinase)IBA
10/2009
1Sevoflurane (Ultane)FDA LinkGeneric
09/2006
1Aprotinin (Trasylol)FDA Link
11/2003
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
11/2003
1Caffeine (No Doz)FDA LinkGeneric
07/2003

Therapy/Procedure

1Coronary Artery Bypass (Coronary Artery Bypass Surgery)
11/2003
1Therapeutics
11/2003