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Wataru Habano Selected Research

Hepatocellular Carcinoma (Hepatoma)

12/2015CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures.
4/2015A CAR-responsive enhancer element locating approximately 31 kb upstream in the 5'-flanking region of rat cytochrome P450 (CYP) 3A1 gene.
1/2015Analysis of DNA methylation landscape reveals the roles of DNA methylation in the regulation of drug metabolizing enzymes.
1/2011Induction of CYP1 family members under low-glucose conditions requires AhR expression and occurs through the nuclear translocation of AhR.

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Wataru Habano Research Topics

Disease

24Neoplasms (Cancer)
09/2021 - 02/2002
12Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 10/2002
7Carcinogenesis
01/2019 - 02/2002
7Aneuploidy (Aneuploid)
07/2005 - 10/2002
5Adenoma (Adenomas)
09/2021 - 03/2003
5Stomach Neoplasms (Stomach Cancer)
01/2017 - 05/2004
4Carcinoma (Carcinomatosis)
09/2021 - 03/2003
4Colonic Neoplasms (Colon Cancer)
01/2021 - 02/2011
4Microsatellite Instability
12/2020 - 10/2002
4Hepatocellular Carcinoma (Hepatoma)
12/2015 - 01/2011
3Lung Neoplasms (Lung Cancer)
01/2023 - 08/2018
3Liver Neoplasms (Liver Cancer)
12/2021 - 12/2013
3Hypertrophy
01/2013 - 10/2011
2Hypoxia (Hypoxemia)
01/2023 - 11/2016
2Adenocarcinoma
10/2004 - 07/2003
1Atrophy
03/2021
1Wilms Tumor (Wilm's Tumor)
04/2018
1Esophageal Neoplasms (Esophageal Cancer)
11/2016
1Hepatoblastoma
12/2013
1Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
09/2011
1Constipation
09/2011
1Diarrhea
09/2011
1Crohn Disease (Crohn's Disease)
05/2010
1Diabetes Mellitus
11/2009
1Pathologic Constriction (Stenosis)
11/2009
1Carotid Stenosis (Carotid Artery Stenosis)
11/2009
1Fibrosis (Cirrhosis)
09/2008
1Liver Cirrhosis (Hepatic Cirrhosis)
09/2008
1Virus Diseases (Viral Diseases)
09/2008
1Chronic Hepatitis C
09/2008

Drug/Important Bio-Agent (IBA)

12DNA (Deoxyribonucleic Acid)IBA
01/2021 - 11/2002
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2023 - 02/2006
4Messenger RNA (mRNA)IBA
09/2021 - 02/2011
4EnzymesIBA
12/2015 - 04/2009
3Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
01/2019 - 12/2013
3Biomarkers (Surrogate Marker)IBA
01/2017 - 06/2003
3hydrogen sulfite (bisulfite)IBA
12/2016 - 04/2009
3Proteins (Proteins, Gene)FDA Link
12/2010 - 02/2002
2DecitabineFDA Link
12/2021 - 04/2018
2MethyltransferasesIBA
12/2021 - 01/2021
2Irinotecan (Camptosar)FDA LinkGeneric
01/2021 - 04/2018
2MucinsIBA
12/2020 - 10/2004
2CateninsIBA
12/2020 - 03/2017
2Benzo(a)pyreneIBA
01/2019 - 08/2018
2Calcibiotic Root Canal SealerIBA
03/2017 - 12/2016
2Cytochrome P-450 CYP1A2 (CYP1A2)IBA
12/2015 - 09/2008
2Cytochrome P-450 CYP1A1 (CYP1A1)IBA
12/2015 - 04/2009
2Complementary DNA (cDNA)IBA
04/2015 - 10/2011
2Glucose (Dextrose)FDA LinkGeneric
12/2013 - 01/2011
2Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
10/2011 - 04/2009
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2010 - 09/2008
2VimentinIBA
02/2002 - 02/2002
1Aryl Hydrocarbon Receptor Nuclear TranslocatorIBA
01/2023
1ChromatinIBA
12/2021
1A-Form DNA (A-DNA)IBA
12/2021
1AntralIBA
03/2021
1LigandsIBA
01/2019
1SmokeIBA
01/2019
1Transcription Factors (Transcription Factor)IBA
08/2018
1WT1 ProteinsIBA
04/2018
1Caspase 3 (Caspase-3)IBA
10/2016
1Fluorouracil (Carac)FDA LinkGeneric
10/2016
1Histone Deacetylase InhibitorsIBA
10/2016
1DepsipeptidesIBA
10/2016
1dimethylethylsilylimidazoleIBA
01/2015
1Activating Transcription Factor 4IBA
12/2013
1indole-3-carbinolIBA
01/2013
1Acetaminophen (Paracetamol)FDA LinkGeneric
01/2013
1Piperonyl ButoxideFDA Link
10/2011
1ClofibrateFDA Link
10/2011
1Cyclin-Dependent Kinases (cdk Proteins)IBA
10/2011
1Cytochrome P-450 CYP2B1 (PROD)IBA
10/2011
1CyclinsIBA
10/2011
1Protein Isoforms (Isoforms)IBA
10/2011
1Phenobarbital (Luminal)FDA Link
10/2011
1Cholinergic Agents (Cholinergics)IBA
09/2011
1Cholinergic ReceptorsIBA
09/2011
1Calcitriol Receptors (Calcitriol Receptor)IBA
02/2011
1Cytochrome P-450 CYP3AIBA
02/2011
1Pregnane X ReceptorIBA
02/2011
1Cytochrome P450 Family 1IBA
01/2011
1IgG Receptors (Fc gamma RI)IBA
05/2010
1Infliximab (Remicade)FDA Link
05/2010
1Plasminogen Activator Inhibitor 1IBA
11/2009
1OligonucleotidesIBA
11/2009
1DioxinsIBA
04/2009
1Hormones (Hormone)IBA
04/2009
1CytochromesIBA
09/2008
1Peptides (Polypeptides)IBA
09/2008
1Taurocholic Acid (Sodium Taurocholate)IBA
09/2008
1AnionsIBA
09/2008
1CytokinesIBA
09/2008
1Organic Cation Transporter 1IBA
09/2008
1polypeptide CIBA
09/2008
1Carbonic Anhydrase IIBA
01/2008
1Keratin-20 (Cytokeratin 20)IBA
01/2008
1beta CateninIBA
01/2008
1Retinal Pigments (Pigments, Visual)IBA
02/2006

Therapy/Procedure

2Drug Therapy (Chemotherapy)
01/2021 - 04/2009
1Carotid Endarterectomy
11/2009