Gordon Guyatt Selected Research

PCSK9 Inhibitors

1/2022	PCSK9 inhibitors and ezetimibe for the reduction of cardiovascular events: a clinical practice guideline with risk-stratified recommendations.
1/2022	Safety of proprotein convertase subtilisin/kexin 9 inhibitors: a systematic review and meta-analysis.
1/2022	PCSK9 inhibitors and ezetimibe with or without statin therapy for cardiovascular risk reduction: a systematic review and network meta-analysis.

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Gordon Guyatt Research Topics

Disease

43	Hemorrhage 05/2024 - 01/2008
31	Critical Illness (Critically Ill) 11/2023 - 09/2003
20	Venous Thromboembolism 10/2023 - 07/2005
17	Infections 01/2024 - 06/2008
15	Stroke (Strokes) 01/2022 - 09/2006
13	Venous Thrombosis (Deep-Vein Thrombosis) 01/2018 - 07/2005
12	COVID-19 08/2023 - 01/2020
11	Pain (Aches) 11/2023 - 09/2005
11	Myocardial Infarction 01/2022 - 01/2002
10	Arthritis (Polyarthritis) 12/2023 - 06/2002
10	Osteoporosis 12/2023 - 08/2002
10	Hypotension (Low Blood Pressure) 01/2023 - 10/2011
10	Postmenopausal Osteoporosis 01/2023 - 08/2002
9	Neoplasms (Cancer) 12/2023 - 11/2005
9	Thrombosis (Thrombus) 12/2021 - 10/2012
9	Thromboembolism 12/2016 - 12/2005
8	Thrombocytopenia (Thrombopenia) 12/2023 - 04/2011
7	Osteoarthritis 12/2023 - 09/2005
7	Pulmonary Embolism 01/2018 - 01/2008
6	Rheumatoid Arthritis 01/2023 - 01/2017
6	Sepsis (Septicemia) 01/2018 - 08/2005
6	Wounds and Injuries (Trauma) 11/2017 - 07/2005
6	Atrial Fibrillation 12/2015 - 09/2006
5	Open Fractures (Compound Fracture) 02/2024 - 06/2011
5	Weight Loss (Weight Reduction) 01/2024 - 09/2014
5	Cardiovascular Diseases (Cardiovascular Disease) 12/2023 - 06/2013
5	Acquired Immunodeficiency Syndrome (AIDS) 11/2023 - 04/2012
5	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2020 - 01/2017
5	Ischemic Stroke 12/2018 - 09/2006
4	Ulcer 05/2024 - 05/2016
4	Overweight 01/2024 - 01/2020
4	Clostridium Infections 12/2023 - 05/2016
4	Ventilator-Associated Pneumonia 12/2023 - 11/2016
4	Osteonecrosis (Kienbock's Disease) 12/2023 - 11/2023
4	Diabetes Mellitus 11/2023 - 01/2022
4	Tibial Fractures (Fracture, Tibial) 07/2023 - 06/2011
4	Renal Insufficiency (Renal Failure) 03/2023 - 12/2005
4	Pneumonia (Pneumonitis) 01/2023 - 05/2016
4	Shock 01/2022 - 11/2017
4	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2021
4	Chronic Renal Insufficiency 01/2021 - 01/2008
4	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 01/2017 - 01/2017
4	Rheumatic Diseases (Rheumatism) 01/2017 - 01/2017
4	Dementia (Dementias) 01/2014 - 01/2009
3	Closed Fractures (Closed Fracture) 02/2024 - 06/2008
3	Hypophosphatasia 11/2023 - 11/2023
3	Vasculitis (Vasculitides) 03/2023 - 01/2021
3	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 03/2023 - 01/2022
3	Hypertension (High Blood Pressure) 01/2023 - 01/2022
3	Hypoparathyroidism 12/2022 - 12/2022
3	Heart Failure 01/2022 - 01/2021
3	Injection Site Reaction 01/2022 - 07/2021
3	Ischemia 12/2021 - 03/2016
3	Body Weight (Weight, Body) 01/2021 - 06/2013

Drug/Important Bio-Agent (IBA)

15	Heparin (Liquaemin)FDA LinkGeneric 12/2023 - 04/2011
15	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 10/2023 - 12/2005
13	AnticoagulantsIBA 01/2023 - 01/2008
11	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022 - 01/2008
10	GlucocorticoidsIBA 12/2023 - 01/2017
9	Dalteparin (Dalteparin Sodium)FDA Link 01/2018 - 01/2008
6	Proton Pump InhibitorsIBA 11/2023 - 05/2016
6	CalciumIBA 12/2022 - 08/2002
6	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 06/2013
6	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 11/2008
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2023 - 02/2015
5	CreatinineIBA 03/2023 - 01/2008
5	Antirheumatic Agents (DMARD)IBA 01/2023 - 01/2017
5	Warfarin (Coumadin)FDA LinkGeneric 12/2015 - 09/2006
4	Pantoprazole (Protonix)FDA LinkGeneric 05/2024 - 07/2017
4	Glucagon-Like Peptide-1 Receptor AgonistsIBA 01/2024 - 01/2021
4	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 03/2023 - 01/2021
4	Anti-Bacterial Agents (Antibiotics)IBA 01/2023 - 01/2012
4	Vitamin D FDA LinkGeneric 01/2017 - 08/2002
3	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2024 - 01/2021
3	N- (4'- fluorobutyrophenone)- 4- (4- chlorophenyl)pyridinium (HPP(+))IBA 11/2023 - 11/2023
3	Antihypertensive Agents (Antihypertensives)IBA 01/2023 - 01/2013
3	Antiviral Agents (Antivirals)IBA 12/2022 - 01/2020
3	Parathyroid Hormone (Parathormone)IBA 12/2022 - 12/2022
3	Intravenous Immunoglobulins (IVIG)FDA Link 12/2022 - 01/2022
3	remdesivirIBA 12/2022 - 01/2020
3	Tranexamic Acid (AMCA)FDA Link 01/2022 - 03/2011
3	Ezetimibe (Zetia)FDA Link 01/2022 - 01/2022
3	PCSK9 InhibitorsIBA 01/2022 - 01/2022
3	SodiumIBA 01/2022 - 01/2021

Therapy/Procedure

61	Therapeutics 12/2023 - 08/2002
10	Critical Care (Surgical Intensive Care) 01/2020 - 12/2005
9	Knee Replacement Arthroplasty (Total Knee Replacement) 12/2023 - 01/2017
7	Artificial Respiration (Mechanical Ventilation) 08/2023 - 09/2003
6	Length of Stay 08/2023 - 09/2006
6	Intramedullary Fracture Fixation 07/2023 - 06/2008
4	Arthroplasty 12/2023 - 09/2005
4	Glycemic Control 11/2023 - 01/2021
4	Injections 01/2022 - 02/2019
4	Hormone Replacement Therapy (Therapy, Hormone Replacement) 01/2020 - 08/2002
3	Blood Transfusion (Blood Transfusions) 03/2024 - 03/2011
3	Drug Therapy (Chemotherapy) 01/2024 - 01/2020
3	Renal Replacement Therapy (Therapies, Renal Replacement) 12/2023 - 07/2017
3	Orthopedic Procedures 11/2023 - 07/2005
3	Intra-Articular Injections 11/2023 - 11/2023
3	Physical Therapy Modalities (Physical Therapy Technique) 11/2023 - 11/2023