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Sridharan Gururangan Selected Research

Exanthema (Rash)

8/2017A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study.
12/2010Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma.

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Sridharan Gururangan Research Topics

Disease

36Neoplasms (Cancer)
01/2023 - 01/2002
34Glioma (Gliomas)
01/2022 - 01/2002
24Brain Neoplasms (Brain Tumor)
10/2021 - 01/2002
21Medulloblastoma
11/2021 - 01/2002
15Glioblastoma (Glioblastoma Multiforme)
11/2021 - 12/2005
4Pinealoma (Pineoblastoma)
01/2020 - 06/2003
4Ependymoma
01/2016 - 01/2002
4Hypoxia (Hypoxemia)
01/2014 - 12/2010
4Astrocytoma (Pilocytic Astrocytoma)
08/2013 - 01/2002
3Diffuse Intrinsic Pontine Glioma
01/2023 - 01/2022
2Neutropenia
01/2021 - 01/2002
2Headache (Headaches)
08/2017 - 03/2006
2Mucositis
08/2017 - 12/2010
2Exanthema (Rash)
08/2017 - 12/2010
2Neoplasm Metastasis (Metastasis)
01/2016 - 11/2013
2Primitive Neuroectodermal Tumors (PNET)
08/2014 - 04/2010
2Hearing Loss (Hearing Impairment)
06/2014 - 04/2014
2Ototoxicity
04/2014 - 08/2008
2Hydrocephalus (Hydrocephaly)
02/2009 - 11/2008
2Disease Progression
07/2002 - 01/2002
1Brain Stem Neoplasms (Brain Stem Tumor)
01/2022
1Leukopenia
01/2021
1Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy)
05/2019
1Polyneuropathies (Polyneuropathy)
05/2019
1Nausea
12/2017
1Edema (Dropsy)
12/2017
1Infratentorial Neoplasms (Posterior Fossa Tumors)
12/2017
1Tuberous Sclerosis (Bourneville's Disease)
08/2017
1Hamartoma
08/2017
1Sarcoma (Soft Tissue Sarcoma)
01/2016

Drug/Important Bio-Agent (IBA)

17Bevacizumab (Avastin)FDA Link
01/2019 - 02/2007
17Irinotecan (Camptosar)FDA LinkGeneric
01/2014 - 01/2002
11Temozolomide (Temodar)FDA LinkGeneric
06/2011 - 02/2003
7O(6)-benzylguanineIBA
10/2009 - 05/2002
6Imatinib Mesylate (Gleevec)FDA Link
10/2012 - 12/2005
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2014 - 11/2008
5Hydroxyurea (Hydrea)FDA LinkGeneric
10/2012 - 12/2005
5Tyrosine Kinase InhibitorsIBA
12/2011 - 09/2005
4Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2014 - 05/2009
4Monoclonal AntibodiesIBA
04/2011 - 01/2006
3Biomarkers (Surrogate Marker)IBA
01/2023 - 01/2016
3dipinacoline glutamateIBA
01/2023 - 01/2022
3Proteins (Proteins, Gene)FDA Link
01/2021 - 02/2008
3Cisplatin (Platino)FDA LinkGeneric
06/2014 - 08/2008
3Carboplatin (JM8)FDA LinkGeneric
03/2012 - 07/2002
3ErbB Receptors (EGF Receptor)IBA
12/2010 - 02/2006
3Topoisomerase I InhibitorsIBA
10/2005 - 04/2004
3Carmustine (FIVB)FDA Link
04/2004 - 05/2002
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
10/2021 - 08/2017
2AZD 6244IBA
10/2021 - 08/2017
2MicroRNAs (MicroRNA)IBA
01/2020 - 08/2014
2RNA (Ribonucleic Acid)IBA
01/2020 - 10/2015
2Vincristine (Oncovin)FDA LinkGeneric
05/2019 - 08/2008
2Formaldehyde (Formol)FDA Link
01/2016 - 11/2013
2ParaffinIBA
01/2016 - 11/2013
2Amyloid Precursor Protein Secretases (beta-Secretase)IBA
08/2015 - 09/2011
23- (4- ((4- chlorophenyl)sulfonyl)- 4- (2,5- difluorophenyl)cyclohexyl)propanoic acidIBA
08/2015 - 09/2011
2Amifostine (Ethyol)FDA LinkGeneric
06/2014 - 08/2008
2Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
08/2013 - 12/2004
2Erlotinib Hydrochloride (CP 358,774)FDA Link
12/2010 - 01/2010
2Sirolimus (Rapamycin)FDA Link
01/2010 - 02/2006
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2010 - 02/2006
2TOR Serine-Threonine KinasesIBA
01/2010 - 02/2006
2laromustine (VNP40101M)IBA
09/2008 - 02/2008
2Alkylating AgentsIBA
09/2008 - 02/2008
2Adenosine Triphosphate (ATP)IBA
05/2007 - 12/2005
2Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
05/2007 - 12/2005
1NivolumabIBA
01/2023
1IpilimumabIBA
01/2023
1B7-H1 AntigenIBA
01/2023
1Cell-Free Nucleic AcidsIBA
11/2021
1Protons (Proton)IBA
07/2021
1palbociclibIBA
01/2021
1Cyclin-Dependent Kinase 4IBA
01/2021
1Retinoblastoma ProteinIBA
01/2021
1tyrosyltyrosine (Tyr-Tyr)IBA
01/2021
11-(carboxymethylthio)tetradecaneIBA
05/2019
1Vinca AlkaloidsIBA
05/2019
1Dexamethasone (Maxidex)FDA LinkGeneric
12/2017
1EverolimusFDA Link
08/2017
1Lipase (Acid Lipase)FDA Link
08/2017
1AmylasesFDA Link
08/2017
1Mitogen-Activated Protein KinasesIBA
08/2017
1Retinaldehyde (Retinal)IBA
08/2017
1A 17 (A-17)IBA
01/2017
1Neoplasm Antigens (Tumor Antigens)IBA
10/2015
13' Untranslated Regions (3' UTR)IBA
10/2015

Therapy/Procedure

21Therapeutics
07/2021 - 01/2002
13Drug Therapy (Chemotherapy)
05/2019 - 01/2002
6Radiotherapy
01/2016 - 01/2002
5Craniospinal Irradiation
07/2021 - 08/2008
4Salvage Therapy
11/2008 - 04/2006
3Hearing Aids (Hearing Aid)
06/2014 - 08/2008
2Immunotherapy
11/2021 - 10/2015
2Proton Therapy
07/2021 - 07/2021
2Chemoradiotherapy
01/2016 - 01/2011
2Aftercare (After-Treatment)
09/2015 - 08/2008
2Radioimmunotherapy
01/2006 - 09/2005
1Craniotomy
12/2017
1Cytoreduction Surgical Procedures
01/2016