Markus Grompe Selected Research

Apolipoproteins B (ApoB)

1/2017

A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia.

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Markus Grompe Research Topics

Disease

20	Fanconi Anemia (Fanconi's Anemia) 05/2024 - 07/2002
17	Neoplasms (Cancer) 05/2024 - 07/2002
12	Tyrosinemias (Tyrosinemia) 01/2017 - 12/2002
10	Liver Diseases (Liver Disease) 10/2023 - 04/2003
6	Bone Marrow Failure Disorders 05/2024 - 11/2002
5	Phenylketonurias (Phenylketonuria) 10/2023 - 09/2014
4	Sepsis (Septicemia) 01/2023 - 11/2013
4	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2018 - 07/2013
4	succinic semialdehyde dehydrogenase deficiency 04/2004 - 07/2002
3	Chromosome Breakage 12/2016 - 05/2004
3	Pancreatic Neoplasms (Pancreatic Cancer) 03/2016 - 10/2012
3	Inborn Genetic Diseases (Disease, Hereditary) 10/2012 - 12/2002
2	Hypersensitivity (Allergy) 01/2023 - 07/2002
2	Carcinoma (Carcinomatosis) 01/2023 - 07/2015
2	Diabetes Mellitus 01/2022 - 11/2016
2	Non-alcoholic Fatty Liver Disease 01/2022 - 01/2021
2	Carcinogenesis 01/2021 - 11/2017
2	Polyploidy 01/2020 - 05/2013
2	Acute Liver Failure (Fulminant Hepatic Failure) 01/2019 - 07/2014
2	Fibrosis (Cirrhosis) 01/2017 - 10/2011
2	Hepatocellular Carcinoma (Hepatoma) 10/2016 - 10/2011
2	Pancreatitis 03/2016 - 01/2013
2	Liver Failure 04/2013 - 10/2011
2	Adenocarcinoma 01/2013 - 10/2012
2	Genomic Instability 09/2008 - 08/2003
2	Seizures (Absence Seizure) 04/2004 - 01/2003
2	Chromosomal Instability (Chromosome Stability) 01/2003 - 07/2002
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2023
1	Lung Neoplasms (Lung Cancer) 01/2023
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2023
1	Cytopenia 01/2022
1	Hemophilia B (Haemophilia B) 01/2021
1	Fever (Fevers) 01/2021
1	Inflammation (Inflammations) 01/2021
1	Neurologic Manifestations (Neurological Manifestations) 06/2020
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2019
1	Colonic Neoplasms (Colon Cancer) 11/2018
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2018
1	Hypercholesterolemia 01/2017
1	Homozygous Familial Hypercholesterolemia 01/2017
1	Liver Cirrhosis (Hepatic Cirrhosis) 10/2016
1	Hyperglycemia 10/2016
1	Multiple Sclerosis 03/2016
1	Heart Arrest (Cardiac Arrest) 03/2016
1	Traumatic Brain Injuries (Traumatic Brain Injury) 03/2016
1	Body Weight (Weight, Body) 09/2015
1	Aplastic Anemia (Anemia, Hypoplastic) 07/2015

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2002
11	fumarylacetoacetase (fumarylacetoacetate hydrolase)IBA 01/2017 - 04/2003
9	DNA (Deoxyribonucleic Acid)IBA 05/2024 - 07/2002
5	EnzymesIBA 01/2018 - 09/2004
5	Tyrosine (L-Tyrosine)FDA Link 01/2017 - 09/2004
4	Metformin (Glucophage)FDA LinkGeneric 05/2024 - 12/2016
4	Acetaminophen (Paracetamol)FDA LinkGeneric 10/2023 - 02/2004
4	Cell-Free Nucleic AcidsIBA 01/2023 - 03/2016
4	Succinate-Semialdehyde Dehydrogenase (Succinic Semialdehyde Dehydrogenase)IBA 04/2004 - 07/2002
3	Oxymetholone (Anadrol)FDA Link 05/2024 - 01/2015
3	AntioxidantsIBA 01/2019 - 03/2008
3	Monoclonal AntibodiesIBA 07/2015 - 10/2012
3	Mitomycin (Mitomycin-C)FDA LinkGeneric 07/2011 - 07/2002
2	Insulin (Novolin)FDA Link 01/2022 - 11/2016
2	CholesterolIBA 01/2019 - 01/2013
2	tempolIBA 04/2014 - 03/2008
2	CytokinesIBA 03/2008 - 11/2002
1	Isoleucine (L-Isoleucine)FDA Link 01/2022
1	Hemoglobins (Hemoglobin)IBA 01/2022
1	Methionine (L-Methionine)FDA Link 01/2022
1	Phospholipases (Phospholipase)IBA 01/2022
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2021
1	Estrogens (Estrogen)FDA Link 01/2021
1	Phenylalanine Hydroxylase (Phenylalanine 4 Monooxygenase)IBA 06/2020
1	Phenylalanine (L-Phenylalanine)FDA Link 06/2020
1	Celecoxib (Celebrex)FDA Link 01/2019
1	Glutathione (Reduced Glutathione)IBA 01/2019
1	Atorvastatin (Lipitor)FDA Link 01/2019
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2018
1	Alanine Transaminase (SGPT)IBA 01/2018
1	Cardiac GlycosidesIBA 01/2017
1	Apolipoproteins B (ApoB)IBA 01/2017
1	oxidized low density lipoproteinIBA 01/2017
1	pimagedine (aminoguanidine)IBA 12/2016
1	Transcription Factors (Transcription Factor)IBA 10/2016
1	succinylacetoneIBA 10/2016
1	Bile Acids and Salts (Bile Acids)IBA 09/2015
1	SRT3025IBA 07/2015
1	Sirtuin 1IBA 07/2015
1	AndrogensIBA 01/2015
1	OsteopontinIBA 01/2015
1	Dopamine (Intropin)FDA LinkGeneric 09/2014
1	Neurotransmitter Agents (Neurotransmitter)IBA 09/2014
1	ResveratrolIBA 04/2014
1	Acetylcysteine (Siran)FDA LinkGeneric 04/2014

Therapy/Procedure

17	Therapeutics 05/2024 - 11/2007
7	Transplantation 10/2023 - 03/2008
3	Chemoprevention 01/2019 - 08/2008
2	Cell Transplantation 10/2023 - 08/2023
1	Oral Administration 01/2019
1	Treatment Delay 01/2019
1	Islets of Langerhans Transplantation 11/2018
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 07/2015