Nikolaos Grigoriadis Selected Research

Tauopathies

1/2022	Novel ADNP Syndrome Mice Reveal Dramatic Sex-Specific Peripheral Gene Expression With Brain Synaptic and Tau Pathologies.
1/2020	Tauopathy in the young autistic brain: novel biomarker and therapeutic target.
10/2013	Repeated immunization of mice with phosphorylated-tau peptides causes neuroinflammation.
7/2011	Moderate environmental enrichment mitigates tauopathy in a neurofibrillary tangle mouse model.
8/2010	Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice.
3/2009	Statins reduce the neurofibrillary tangle burden in a mouse model of tauopathy.
7/2008	A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics.
10/2006	Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein.

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Nikolaos Grigoriadis Research Topics

Disease

33	Multiple Sclerosis 07/2023 - 07/2007
19	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 03/2024 - 12/2003
17	Inflammation (Inflammations) 05/2024 - 01/2005
15	Relapsing-Remitting Multiple Sclerosis 01/2023 - 07/2002
12	Demyelinating Diseases (Demyelinating Disease) 07/2023 - 12/2009
12	Neuroinflammatory Diseases 01/2023 - 03/2006
8	Stroke (Strokes) 10/2022 - 08/2008
8	Tauopathies 01/2022 - 10/2006
8	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 10/2006
7	Traumatic Brain Injuries (Traumatic Brain Injury) 10/2013 - 03/2006
6	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2024 - 10/2006
5	Atrophy 04/2024 - 01/2002
5	Infections 03/2024 - 01/2009
5	Neoplasms (Cancer) 07/2023 - 01/2003
5	Gliosis 01/2023 - 10/2006
5	Disease Progression 11/2020 - 06/2008
4	Neuromyelitis Optica (Devic's Disease) 12/2022 - 03/2010
4	Brain Diseases (Brain Disorder) 01/2021 - 04/2008
4	Encephalitis (Encephalitis, Rasmussen) 08/2010 - 12/2003
4	Closed Head Injuries 12/2009 - 03/2006
3	Obesity 03/2024 - 01/2023
3	COVID-19 01/2023 - 01/2021
3	Fatigue 02/2022 - 10/2004
3	Wounds and Injuries (Trauma) 12/2009 - 07/2007
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 03/2024 - 02/2017
2	Encephalomyelitis (Myeloencephalitis) 10/2023 - 02/2006
2	Autism Spectrum Disorder 05/2023 - 06/2019
2	Nervous System Diseases (Neurological Disorders) 01/2023 - 10/2013
2	Chronic Progressive Multiple Sclerosis 01/2022 - 01/2020
2	Neurologic Manifestations (Neurological Manifestations) 09/2021 - 10/2006
2	Progressive Multifocal Leukoencephalopathy 01/2021 - 08/2011
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 02/2017
2	Cognitive Dysfunction 06/2020 - 01/2017
2	Autistic Disorder (Autism) 01/2020 - 01/2019
2	Pathologic Processes 01/2018 - 01/2017
2	Thrombosis (Thrombus) 01/2015 - 01/2015
2	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 09/2014 - 08/2008
2	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2013 - 07/2009
2	Dementia (Dementias) 07/2011 - 03/2009
2	Autoimmune Diseases (Autoimmune Disease) 12/2009 - 01/2005
2	Scrapie 07/2009 - 10/2006
2	Central Nervous System Diseases (CNS Diseases) 07/2007 - 12/2003
1	Cerebellar Diseases (Cerebellar Syndrome) 05/2024
1	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 05/2024
1	Muscular Atrophy (Muscle Atrophy) 05/2024
1	Hyperhomocysteinemia 03/2024
1	Dysbiosis 03/2024
1	Atrial Fibrillation 03/2024
1	Hypertension (High Blood Pressure) 03/2024
1	Atherosclerosis 03/2024
1	Dyslipidemias (Dyslipidemia) 03/2024
1	Diabetes Mellitus 03/2024
1	Insulin Resistance 03/2024
1	Mood Disorders (Mood Disorder) 07/2023

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 05/2024 - 01/2007
7	Biomarkers (Surrogate Marker)IBA 12/2022 - 01/2019
6	Peptides (Polypeptides)IBA 01/2019 - 01/2005
5	AntibodiesIBA 05/2024 - 07/2009
4	Nogo ReceptorsIBA 01/2023 - 10/2016
4	LigandsIBA 01/2023 - 01/2005
4	Natalizumab (Tysabri)FDA Link 01/2021 - 08/2011
4	Amyloid (Amyloid Fibrils)IBA 07/2011 - 10/2006
3	Galectin 3 (LGALS3)IBA 03/2024 - 01/2020
3	VaccinesIBA 01/2023 - 01/2021
3	Fingolimod Hydrochloride (FTY720)FDA Link 01/2023 - 01/2016
3	Neutralizing AntibodiesIBA 01/2023 - 01/2016
3	ChemokinesIBA 12/2022 - 12/2015
3	CytokinesIBA 12/2022 - 07/2011
3	nitazoxanide (NTZ)FDA Link 01/2021 - 01/2016
3	tau Proteins (tau Protein)IBA 10/2013 - 10/2006
3	AntigensIBA 07/2007 - 01/2005
2	Nogo Receptor 1IBA 01/2023 - 01/2021
2	EnzymesIBA 01/2023 - 09/2021
2	Complement C5 (Complement 5)IBA 01/2023 - 01/2023
2	Complement System Proteins (Complement)IBA 01/2023 - 01/2023
2	Myelin-Oligodendrocyte GlycoproteinIBA 12/2022 - 11/2020
2	Retinaldehyde (Retinal)IBA 12/2022 - 07/2022
2	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 02/2022 - 06/2021
2	InterferonsIBA 01/2022 - 01/2016
2	Immunoglobulin G (IgG)IBA 02/2021 - 01/2009
2	Metalloproteases (Metalloproteinases)IBA 07/2019 - 02/2018
2	Caspase 3 (Caspase-3)IBA 11/2018 - 12/2009
2	LectinsIBA 01/2018 - 03/2009
2	Interferon-betaIBA 01/2016 - 07/2002
2	Prion ProteinsIBA 01/2013 - 07/2009
2	Therapeutic UsesIBA 07/2011 - 01/2011
2	DNA (Deoxyribonucleic Acid)IBA 07/2007 - 03/2006
2	alpha-Fetoproteins (alpha-Fetoprotein)IBA 01/2007 - 03/2006
1	LipopolysaccharidesIBA 05/2024
1	StathminIBA 03/2024
1	Indicators and Reagents (Reagents)IBA 03/2024
1	AdipokinesIBA 03/2024
1	Lipoprotein(a)IBA 03/2024

Therapy/Procedure

20	Therapeutics 07/2023 - 03/2007
8	Transplantation 01/2022 - 12/2003
6	Immunomodulation 10/2023 - 06/2008
5	Immunotherapy 07/2023 - 10/2006
3	Cognitive Training 06/2020 - 01/2017
2	Denervation 01/2003 - 01/2002
1	Polypharmacy 07/2023