Erich Gnaiger Selected Research

Oxygen (Dioxygen)

1/2024	Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia.
1/2018	Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics.
1/2018	Exercise Performance, Muscle Oxygen Extraction and Blood Cell Mitochondrial Respiration after Repeated-Sprint and Sprint Interval Training in Hypoxia: A Pilot Study.
11/2015	Cytochrome redox states and respiratory control in mouse and beef heart mitochondria at steady-state levels of hypoxia.
9/2012	The role of haemoglobin mass on VO(2)max following normobaric 'live high-train low' in endurance-trained athletes.
12/2011	Endogenous myoglobin in breast cancer is hypoxia-inducible by alternative transcription and functions to impair mitochondrial activity: a role in tumor suppression?
10/2011	Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans.
2/2010	Mitochondrial bioenergetic adaptations of breast cancer cells to aglycemia and hypoxia.
1/2010	Cell respiration under hypoxia: facts and artefacts in mitochondrial oxygen kinetics.
2/2008	Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism.

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Erich Gnaiger Research Topics

Disease

14	Hypoxia (Hypoxemia) 01/2024 - 01/2002
7	Neoplasms (Cancer) 08/2022 - 02/2010
6	Mitochondrial Diseases (Mitochondrial Disease) 08/2022 - 06/2002
4	Prostatic Neoplasms (Prostate Cancer) 04/2021 - 01/2015
3	Fatigue 11/2021 - 12/2014
2	Iron Deficiencies 01/2019 - 11/2017
2	Breast Neoplasms (Breast Cancer) 12/2011 - 02/2010
2	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 06/2011 - 01/2002
2	Inflammation (Inflammations) 10/2010 - 01/2006
2	Ischemia 02/2008 - 06/2002
1	Failure to Thrive 06/2023
1	Hemorrhage 12/2021
1	Thrombocytopenia (Thrombopenia) 12/2021
1	Disease Susceptibility (Diathesis) 12/2021
1	Hemochromatosis (Bronze Diabetes) 11/2021
1	Restless Legs Syndrome (Restless Legs) 01/2019
1	Hemolysis 01/2019
1	Pain (Aches) 10/2018
1	Seizures (Absence Seizure) 01/2018
1	Temporal Lobe Epilepsy 01/2018
1	Iron Overload 11/2017
1	Hypothermia 01/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 11/2016
1	Myocardial Infarction 11/2016
1	Starvation 01/2015
1	Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy) 06/2012
1	Overweight 01/2012
1	Heart Diseases (Heart Disease) 12/2011
1	Heart Failure 12/2011
1	Wounds and Injuries (Trauma) 12/2011
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 06/2011
1	Reperfusion Injury 10/2008
1	Edema (Dropsy) 10/2008

Drug/Important Bio-Agent (IBA)

14	Oxygen (Dioxygen)IBA 01/2024 - 01/2002
5	Succinic Acid (Succinate)IBA 01/2024 - 01/2012
5	Proteins (Proteins, Gene)FDA Link 01/2018 - 11/2004
4	Cytochromes c (Cytochrome c)IBA 11/2015 - 04/2002
3	Glutamic Acid (Glutamate)FDA Link 01/2024 - 01/2012
3	NAD (NADH)IBA 01/2024 - 01/2017
3	IronIBA 11/2021 - 11/2017
3	EnzymesIBA 04/2021 - 12/2011
3	Messenger RNA (mRNA)IBA 04/2021 - 12/2011
3	Mitochondrial DNA (mtDNA)IBA 01/2020 - 06/2012
3	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 02/2010
3	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 01/2017 - 04/2002
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2015 - 10/2011
3	GlucocorticoidsIBA 06/2011 - 01/2002
2	Oxidoreductases (Dehydrogenase)IBA 01/2024 - 01/2017
2	malic acid (malate)IBA 01/2020 - 01/2012
2	NucleotidesIBA 01/2018 - 09/2003
2	Dexamethasone (Maxidex)FDA LinkGeneric 06/2011 - 09/2003
1	CalciumIBA 01/2024
1	UbiquinoneIBA 01/2024
1	succinyl-coenzyme A (succinyl-CoA)IBA 01/2024
1	QuinonesIBA 01/2024
1	Ketoglutarate Dehydrogenase Complex (Oxoglutarate Dehydrogenase)IBA 01/2024
1	Blood Glucose (Blood Sugar)IBA 06/2023
1	Phosphotransferases (Kinase)IBA 08/2022
1	Culture MediaIBA 08/2022
1	Sunitinib (Sutent)FDA Link 08/2022
1	Dietary IronIBA 11/2021
1	Superoxides (Superoxide)IBA 01/2019
1	Dopamine Agents (Dopaminergic Agents)IBA 01/2019
1	ElectrolytesIBA 01/2019
1	Aconitate Hydratase (Aconitase)IBA 01/2019
1	Iron Regulatory Protein 2IBA 01/2019
1	Heme Oxygenase-1IBA 01/2019
1	thiamine triphosphorate (TTP)IBA 10/2018
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 07/2018
1	TensinsIBA 07/2018
1	acylcarnitineIBA 01/2018
1	Amino Acids FDA Link 01/2018
1	Opioid Analgesics (Opioids)IBA 01/2018
1	CarbonIBA 01/2018
1	NitrogenIBA 01/2018
1	Kainic Acid (Kainate)IBA 01/2018
1	EnkephalinsIBA 01/2018
1	Phosphates (Orthophosphate)IBA 01/2018
1	PentosesIBA 01/2018
1	purineIBA 01/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2017
1	IntegrinsIBA 11/2016
1	LipidsIBA 11/2016
1	CytochromesIBA 11/2015
1	Triglycerides (Triacylglycerol)IBA 01/2015
1	Lactic Acid (Lactate)FDA LinkGeneric 12/2014
1	Carbon MonoxideIBA 09/2012
1	Codon (Codons)IBA 12/2011
1	MyoglobinIBA 12/2011
1	Carbonic Anhydrase IXIBA 12/2011
1	Adenosine Triphosphate (ATP)IBA 06/2011
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2010
1	Cardioplegic SolutionsIBA 10/2008
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 10/2008

Therapy/Procedure

4	Therapeutics 11/2021 - 12/2011
1	Blood Component Removal (Apheresis) 12/2021
1	Precision Medicine 11/2016
1	Endurance Training 10/2011
1	Resistance Training 10/2011
1	Laparotomy 10/2010