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Ian H Gilbert Selected Research

Cardiotoxicity

11/2023Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.

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Ian H Gilbert Research Topics

Disease

18African Trypanosomiasis (Nagana)
11/2015 - 07/2003
17Malaria
01/2022 - 07/2002
10Visceral Leishmaniasis (Kala Azar)
10/2023 - 04/2010
6Chagas Disease (American Trypanosomiasis)
10/2023 - 05/2005
5Infections
11/2023 - 10/2004
4Prion Diseases (Transmissible Spongiform Encephalopathies)
11/2008 - 04/2003
3Schistosomiasis (Bilharziasis)
12/2023 - 01/2012
3Trypanosomiasis
01/2022 - 12/2009
3Neoplasms (Cancer)
01/2013 - 07/2002
2Communicable Diseases (Infectious Diseases)
12/2023 - 01/2013
2Bacterial Infections (Bacterial Infection)
11/2023 - 07/2002
2Tuberculosis (Tuberculoses)
10/2022 - 01/2021
2Leishmaniasis
04/2010 - 05/2005
2Scrapie
10/2004 - 04/2003
1Infertility (Sterility)
01/2024
1Cardiotoxicity
11/2023
1Sepsis (Septicemia)
05/2023
1Gram-Negative Bacterial Infections
04/2023
1Neglected Diseases
11/2021
1Plague (Bubonic Plague)
11/2019
1Cryptosporidiosis
01/2019
1Mycoses (Diseases, Fungus)
06/2015
1Toxoplasmosis
12/2009
1Campylobacter Infections (Campylobacter Infection)
02/2009
1Parasitic Diseases (Parasitic Disease)
05/2005

Drug/Important Bio-Agent (IBA)

6EnzymesIBA
11/2019 - 08/2007
4Proteasome Endopeptidase Complex (Proteasome)IBA
10/2023 - 10/2007
4glycylpeptide N-tetradecanoyltransferaseIBA
11/2015 - 04/2010
4Phosphogluconate Dehydrogenase (Dehydrogenase, Phosphogluconate)IBA
08/2010 - 07/2003
3Praziquantel (Biltricide)FDA Link
12/2023 - 01/2012
3Anti-Bacterial Agents (Antibiotics)IBA
11/2023 - 02/2004
3Cyclin-Dependent Kinases (cdk Proteins)IBA
07/2023 - 01/2018
3Proteins (Proteins, Gene)FDA Link
01/2022 - 04/2003
3Prion ProteinsIBA
10/2007 - 04/2003
3Congo RedIBA
10/2007 - 06/2003
2Proteasome InhibitorsIBA
10/2023 - 01/2021
2Lysine-tRNA LigaseIBA
10/2022 - 01/2019
2Protein Kinases (Protein Kinase)IBA
12/2021 - 11/2017
2Phosphotransferases (Kinase)IBA
12/2021 - 01/2018
2GSK3186899IBA
01/2019 - 01/2018
2trypanothione synthetaseIBA
01/2012 - 12/2009
2DeoxyuridineIBA
10/2011 - 02/2005
2dUTP pyrophosphataseIBA
10/2011 - 02/2011
2PurinesIBA
08/2010 - 08/2005
2thiolactomycinIBA
09/2005 - 02/2004
2PrPSc ProteinsIBA
10/2004 - 04/2003
1Male Contraceptive Agents (Male Contraceptives)IBA
01/2024
1Contraceptive Agents (Contraceptives)IBA
12/2023
1benzofuranIBA
11/2023
1Carbapenems (Carbapenem Antibiotics)IBA
05/2023
1PiperazinesIBA
08/2022
1artemisinin (artemisinine)IBA
01/2022
1Acetate-CoA Ligase (Acetyl CoA Synthetase)IBA
01/2022
11-Phosphatidylinositol 4-Kinase (1 Phosphatidylinositol 4 Kinase)IBA
12/2021
1benzothiopheneIBA
01/2021
1Phe Transfer RNAIBA
01/2021
1Phenylalanine (L-Phenylalanine)FDA Link
01/2021
1Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA
01/2021
1PyrimidinesIBA
10/2020
1miltefosine (Impavido)IBA
01/2019
1benzonidazole (benznidazole)IBA
01/2017
1NifurtimoxIBA
01/2017
1prolyl T RNA synthetaseIBA
01/2017
1Antifungal AgentsIBA
06/2015
1Peptide Elongation Factor 2 (EF-2)IBA
01/2015
1Guanosine Triphosphate (GTP)IBA
01/2015
1DDD107498IBA
01/2015
1Messenger RNA (mRNA)IBA
01/2015
1SulfonamidesIBA
12/2014
1pyrazoleIBA
12/2014
1N- acetylglucosaminyl- phosphatidylinositol de-N-acetylaseIBA
03/2014
1ZincIBA
03/2014
1ethyl 5- ((2,5- dimethyl- 1- (2- (trifluoromethyl)phenyl)pyrrol- 3- yl)methylene)- 2- methyl- 4- oxo- 1H- pyrrole- 3- carboxylateIBA
04/2013
1Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2013
1HydroquinonesIBA
02/2012
1AnthelminticsIBA
01/2012
1trypanothione reductaseIBA
10/2011
1triphosphoric acid (triphosphate)IBA
02/2011
1NucleosidesIBA
08/2010
1Antimalarials (Antimalarial Agents)IBA
05/2010
1PolymersIBA
04/2010
1Fatty Acids (Saturated Fatty Acids)IBA
12/2009
1pteridine reductaseIBA
07/2009
1Peptides (Polypeptides)IBA
11/2008
1QuinuclidinesIBA
11/2007
1Phosphates (Orthophosphate)IBA
08/2007
1PentosesIBA
08/2007
1melamineIBA
01/2006
1Pentamidine (NebuPent)FDA LinkGeneric
01/2006
1Type II Fatty Acid SynthaseIBA
09/2005
1Farnesyl-Diphosphate Farnesyltransferase (Squalene Synthase)IBA
05/2005
1pyrimidineIBA
02/2005
1PolyaminesIBA
08/2003
1Coloring Agents (Dyes)IBA
06/2003
1Amyloid (Amyloid Fibrils)IBA
06/2003

Therapy/Procedure

5Therapeutics
04/2023 - 12/2009
1Mass Drug Administration
12/2023
1Oral Administration
01/2019
1Drug Therapy (Chemotherapy)
04/2016
1Combination Drug Therapy (Combination Chemotherapy)
04/2010