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E Giardino Selected Research

Neoplasms (Cancer)

1/2021The cytoskeleton actin binding protein filamin A impairs both IGF2 mitogenic effects and the efficacy of IGF1R inhibitors in adrenocortical cancer cells.
1/2021Octreotide and pasireotide effects on medullary thyroid carcinoma (MTC) cells growth, migration and invasion.
1/2019Cytoskeleton actin-binding proteins in clinical behavior of pituitary tumors.
1/2019Cofilin is a mediator of RET-promoted medullary thyroid carcinoma cell migration, invasion and proliferation.
10/2017Cofilin is a cAMP effector in mediating actin cytoskeleton reorganization and steroidogenesis in mouse and human adrenocortical tumor cells.
10/2016Dopamine receptor type 2 (DRD2) inhibits migration and invasion of human tumorous pituitary cells through ROCK-mediated cofilin inactivation.
11/2014Filamin A in somatostatin and dopamine receptor regulation in pituitary and the role of cAMP/PKA dependent phosphorylation.
8/2014Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells.

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E Giardino Research Topics

Disease

8Neoplasms (Cancer)
01/2021 - 08/2014
7Pituitary Neoplasms (Pituitary Adenoma)
01/2019 - 08/2014
3Adenoma (Adenomas)
10/2017 - 03/2014
2Thyroid Neoplasms (Thyroid Cancer)
01/2021 - 01/2019
1Adrenal Cortex Neoplasms (Adrenocortical Cancer)
01/2021
1Melanoma (Melanoma, Malignant)
01/2021
1Adrenocortical Carcinoma
01/2021
1Neoplasm Metastasis (Metastasis)
01/2019
1Adrenocortical Adenoma (Disease, Conn's)
10/2017
1Prolactinoma (Prolactinomas)
03/2014
1Thrombosis (Thrombus)
10/2001

Drug/Important Bio-Agent (IBA)

5FilaminsIBA
01/2021 - 08/2014
5Proteins (Proteins, Gene)FDA Link
01/2019 - 08/2014
4Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
01/2019 - 11/2014
4somatostatin receptor 2IBA
01/2018 - 08/2014
3Actin Depolymerizing Factors (Cofilins)IBA
01/2019 - 10/2016
3Dopamine Receptors (Dopamine Receptor)IBA
01/2019 - 10/2016
2Carrier Proteins (Binding Protein)IBA
01/2021 - 01/2019
2Dopamine (Intropin)FDA LinkGeneric
01/2019 - 11/2014
1pasireotideIBA
01/2021
1Octreotide (Sandostatin)FDA LinkGeneric
01/2021
1Insulin-Like PeptidesIBA
01/2021
1Microfilament Proteins (Actin Binding Proteins)IBA
01/2019
1Hydrocortisone (Cortisol)FDA LinkGeneric
10/2017
1Biomarkers (Surrogate Marker)IBA
10/2016
1Cyclin D1IBA
03/2014
1DNA (Deoxyribonucleic Acid)IBA
03/2014
1ferric chlorideIBA
10/2001
1elarofibanIBA
10/2001

Therapy/Procedure

5Therapeutics
01/2021 - 08/2014