Robert E Gerszten Selected Research

Trastuzumab (Herceptin)

1/2020	Changes in Citric Acid Cycle and Nucleoside Metabolism Are Associated with Anthracycline Cardiotoxicity in Patients with Breast Cancer.
9/2015	Longitudinal Changes in Multiple Biomarkers Are Associated with Cardiotoxicity in Breast Cancer Patients Treated with Doxorubicin, Taxanes, and Trastuzumab.
3/2014	Early increases in multiple biomarkers predict subsequent cardiotoxicity in patients with breast cancer treated with doxorubicin, taxanes, and trastuzumab.
9/2012	Assessment of echocardiography and biomarkers for the extended prediction of cardiotoxicity in patients treated with anthracyclines, taxanes, and trastuzumab.
5/2011	Early detection and prediction of cardiotoxicity in chemotherapy-treated patients.

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Robert E Gerszten Research Topics

Disease

21	Insulin Resistance 04/2024 - 01/2008
17	Inflammation (Inflammations) 01/2024 - 08/2005
17	Cardiovascular Diseases (Cardiovascular Disease) 10/2022 - 07/2008
15	Atherosclerosis 03/2024 - 10/2003
13	Type 2 Diabetes Mellitus (MODY) 01/2023 - 04/2011
13	Neoplasms (Cancer) 01/2023 - 03/2005
12	Heart Failure 05/2024 - 10/2007
11	Obesity 05/2024 - 09/2009
11	Myocardial Infarction 01/2022 - 04/2008
6	Cardiotoxicity 12/2022 - 05/2011
6	Breast Neoplasms (Breast Cancer) 12/2022 - 05/2011
6	COVID-19 10/2021 - 06/2020
5	Infections 02/2024 - 01/2017
5	Dyslipidemias (Dyslipidemia) 12/2023 - 06/2010
5	Hypertension (High Blood Pressure) 01/2023 - 04/2008
5	Ischemia 01/2021 - 12/2005
5	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2018 - 06/2009
4	Poisoning 01/2023 - 05/2017
4	Stroke (Strokes) 01/2023 - 01/2019
4	Non-alcoholic Fatty Liver Disease 01/2022 - 06/2015
4	Coronary Disease (Coronary Heart Disease) 01/2022 - 01/2021
4	Weight Loss (Weight Reduction) 01/2021 - 04/2011
3	Body Weight (Weight, Body) 04/2024 - 11/2023
3	Alzheimer Disease (Alzheimer's Disease) 11/2023 - 12/2017
3	Fibrosis (Cirrhosis) 11/2023 - 12/2016
3	Frailty 11/2023 - 01/2019
3	Dementia (Dementias) 01/2023 - 12/2017
3	Ischemic Stroke 01/2023 - 05/2013
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2021 - 12/2005
3	Thrombosis (Thrombus) 01/2020 - 03/2002
3	Diabetes Mellitus 01/2018 - 05/2012
3	Pulmonary Arterial Hypertension 01/2018 - 10/2007
3	Necrosis 01/2017 - 06/2011
3	ST Elevation Myocardial Infarction 01/2016 - 04/2008
3	Myocardial Ischemia (Ischemic Heart Diseases) 06/2011 - 12/2005
3	Atherosclerotic Plaque (Atheroma) 01/2009 - 07/2005
2	Cognitive Dysfunction 11/2023 - 10/2021
2	Renal Insufficiency (Renal Failure) 11/2023 - 01/2012
2	Aortic Valve Stenosis (Aortic Stenosis) 11/2023 - 01/2018
2	Atrial Fibrillation 01/2023 - 11/2016
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2023 - 01/2020
2	Hypertrophy 01/2021 - 12/2016

Drug/Important Bio-Agent (IBA)

44	Biomarkers (Surrogate Marker)IBA 11/2023 - 12/2005
34	Proteins (Proteins, Gene)FDA Link 02/2024 - 08/2005
15	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 01/2008
13	LipidsIBA 08/2023 - 07/2008
9	Branched-Chain Amino AcidsIBA 04/2024 - 04/2011
8	ProteomeIBA 01/2024 - 12/2019
8	Blood Proteins (Serum Proteins)IBA 11/2023 - 06/2011
7	Amino Acids FDA Link 01/2021 - 07/2008
6	Triglycerides (Triacylglycerol)IBA 12/2023 - 06/2010
6	C-Reactive ProteinIBA 08/2023 - 03/2014
6	Troponin IIBA 01/2017 - 02/2010
6	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2016 - 04/2008
5	Insulin (Novolin)FDA Link 01/2023 - 04/2011
5	Trastuzumab (Herceptin)FDA Link 01/2020 - 05/2011
5	Isoleucine (L-Isoleucine)FDA Link 01/2018 - 01/2008
4	Metformin (Glucophage)FDA LinkGeneric 03/2024 - 12/2013
4	EnzymesIBA 11/2023 - 07/2007
4	Cyanides (Isocyanides)IBA 01/2023 - 05/2017
4	CholesterolIBA 01/2023 - 07/2015
4	Leucine (L-Leucine)FDA Link 01/2023 - 01/2008
4	AnthracyclinesIBA 12/2022 - 05/2011
4	HDL CholesterolIBA 10/2022 - 03/2013
4	Peptides (Polypeptides)IBA 01/2021 - 08/2008
4	Lipoproteins (Lipoprotein)IBA 01/2019 - 04/2017
4	ApolipoproteinsIBA 11/2018 - 01/2009
4	pro-brain natriuretic peptide (1-76)IBA 01/2016 - 04/2008
4	Apolipoproteins E (ApoE)IBA 09/2009 - 07/2005
3	Natriuretic PeptidesIBA 05/2024 - 01/2016
3	LDL CholesterolIBA 12/2023 - 11/2018
3	LigandsIBA 11/2023 - 01/2017
3	ChemokinesIBA 11/2023 - 05/2006
3	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2022 - 03/2014
3	Tryptophan (L-Tryptophan)FDA Link 01/2022 - 05/2012
3	Angiotensin-Converting Enzyme 2IBA 01/2021 - 01/2018
3	Lactic Acid (Lactate)FDA LinkGeneric 01/2021 - 06/2011
3	acylcarnitineIBA 01/2021 - 07/2015
3	AntibodiesIBA 01/2020 - 08/2008
3	HDL LipoproteinsIBA 01/2019 - 03/2013
3	Protein Isoforms (Isoforms)IBA 11/2018 - 03/2008
3	Phenylalanine (L-Phenylalanine)FDA Link 01/2018 - 01/2016
3	Glutamic Acid (Glutamate)FDA Link 12/2017 - 05/2012
3	TroponinIBA 04/2017 - 06/2010
3	Clopidogrel (Plavix)FDA Link 01/2016 - 04/2008
3	Troponin T (Troponin T1)IBA 01/2016 - 06/2010
3	Peroxidase (Myeloperoxidase)IBA 01/2016 - 03/2014
3	Taxoids (Taxanes)IBA 09/2015 - 09/2012
3	NucleotidesIBA 05/2012 - 07/2008
2	N-lactoyl-phenylalanineIBA 03/2024 - 11/2023
2	Chemokine CX3CL1IBA 11/2023 - 01/2021
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2023 - 01/2014
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2023 - 01/2020
2	glyoxylic acid (glyoxylate)IBA 01/2023 - 01/2020
2	NucleosidesIBA 01/2022 - 01/2020
2	Angiopoietin-2IBA 10/2021 - 05/2021
2	AKB-9778IBA 10/2021 - 05/2021

Therapy/Procedure

14	Therapeutics 01/2022 - 12/2005
4	Drug Therapy (Chemotherapy) 12/2022 - 05/2011
3	Transcatheter Aortic Valve Replacement 11/2023 - 03/2016