Rita Gerardy-Schahn Selected Research

Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)

1/2023	Rescue of synaptic and cognitive functions in polysialic acid-deficient mice and dementia models by short polysialic acid fragments.
12/2017	Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells.
1/2017	Polysialylation at Early Stages of Oligodendrocyte Differentiation Promotes Myelin Repair.
1/2015	Schizophrenia-like phenotype of polysialyltransferase ST8SIA2-deficient mice.
8/2014	A crucial role for polysialic acid in developmental interneuron migration and the establishment of interneuron densities in the mouse prefrontal cortex.
10/2013	Soluble polysialylated NCAM: a novel player of the innate immune system in the lung.
1/2013	Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration.
2/2012	Restoration of synaptic plasticity and learning in young and aged NCAM-deficient mice by enhancing neurotransmission mediated by GluN2A-containing NMDA receptors.
6/2010	Polysialic acid affects pathophysiological consequences of status epilepticus.
3/2010	Neural cell adhesion molecule-associated polysialic acid regulates synaptic plasticity and learning by restraining the signaling through GluN2B-containing NMDA receptors.

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Rita Gerardy-Schahn Research Topics

Disease

12	Neoplasms (Cancer) 01/2019 - 08/2003
8	Schizophrenia (Dementia Praecox) 01/2023 - 10/2009
6	Infections 01/2023 - 08/2007
4	Epilepsy (Aura) 12/2018 - 07/2007
4	Neuroblastoma 01/2018 - 08/2003
3	Neoplasm Metastasis (Metastasis) 12/2017 - 01/2005
2	Meningitis 01/2016 - 02/2014
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 07/2015 - 01/2013
2	Mental Disorders (Mental Disorder) 08/2014 - 04/2014
2	Proteinuria 08/2013 - 08/2012
2	Seizures (Absence Seizure) 08/2013 - 04/2008
2	Status Epilepticus (Complex Partial Status Epilepticus) 06/2010 - 04/2008
1	Alzheimer Disease (Alzheimer's Disease) 01/2023
1	Dementia (Dementias) 01/2023
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2020
1	Autoimmune Diseases (Autoimmune Disease) 12/2020
1	Meningococcal Infections 01/2018
1	Rhabdomyosarcoma 12/2017
1	Demyelinating Diseases (Demyelinating Disease) 01/2017
1	Multiple Sclerosis 01/2017
1	Memory Disorders (Memory Loss) 04/2016
1	Adenoviridae Infections (Adenovirus Infections) 07/2015
1	Lung Neoplasms (Lung Cancer) 07/2015
1	Autistic Disorder (Autism) 04/2014
1	Bipolar Disorder (Manic Depressive Psychosis) 04/2014
1	Pathologic Processes 03/2014
1	Autism Spectrum Disorder 11/2013
1	Chronic Obstructive Pulmonary Disease (COPD) 10/2013
1	Ataxia (Dyssynergia) 08/2013
1	Intellectual Disability (Idiocy) 08/2013
1	Hemorrhage 08/2013
1	Disease Susceptibility (Diathesis) 08/2013
1	Muscular Dystrophies (Muscular Dystrophy) 03/2013
1	Infantile Spasms (West Syndrome) 02/2013
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2013
1	Nephrotic Syndrome (Syndrome, Nephrotic) 08/2012
1	Autosomal Recessive 3 Severe Congenital Neutropenia 01/2009
1	Contact Dermatitis (Eczema, Contact) 11/2008
1	Bacterial Meningitis 09/2007
1	Sepsis (Septicemia) 09/2007
1	Temporal Lobe Epilepsy 07/2007
1	Hydrocephalus (Hydrocephaly) 12/2005
1	Sialic Acid Storage Disease (Salla Disease) 09/2005
1	Carcinogenesis 08/2004
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 08/2004

Drug/Important Bio-Agent (IBA)

21	polysialic acidIBA 01/2023 - 08/2003
17	Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA 01/2023 - 08/2003
8	Polysaccharides (Glycans)IBA 12/2020 - 08/2007
5	CMP- N- acetylneuraminate- poly- alpha- 2,8- sialosyl sialyltransferaseIBA 01/2017 - 10/2009
4	polysialyl neural cell adhesion moleculeIBA 04/2016 - 08/2003
3	Capsules (Microcapsules)IBA 01/2023 - 09/2007
3	Proteins (Proteins, Gene)FDA Link 12/2020 - 08/2007
3	VaccinesIBA 01/2018 - 02/2014
3	CarbohydratesIBA 12/2017 - 08/2003
3	EnzymesIBA 12/2017 - 08/2004
3	N-Acetylneuraminic Acid (Sialic Acid)IBA 03/2014 - 09/2005
2	LigandsIBA 01/2019 - 01/2018
2	Cytidine Monophosphate N-Acetylneuraminic AcidIBA 08/2013 - 09/2005
2	PolymersIBA 09/2012 - 08/2003
2	PlasticsIBA 04/2008 - 07/2007
1	Meningococcal Vaccines (Meningococcal Vaccine)IBA 12/2020
1	Immunoglobulins (Immunoglobulin)IBA 12/2020
1	Immune Checkpoint InhibitorsIBA 01/2019
1	AntibodiesIBA 01/2019
1	Antiviral Agents (Antivirals)IBA 01/2019
1	LectinsIBA 12/2018
1	polyornithineIBA 12/2018
1	Laminin (Merosin)IBA 12/2018
1	Transcription Factors (Transcription Factor)IBA 12/2018
1	Carrier Proteins (Binding Protein)IBA 01/2018
1	AntigensIBA 01/2018
1	GlycoconjugatesIBA 01/2018
1	endo-N-acetylneuraminidaseIBA 01/2018
1	LuciferasesIBA 12/2017
1	CuprizoneIBA 01/2017
1	adenovirus receptorIBA 07/2015
1	ParaffinIBA 03/2014
1	Sialic AcidsIBA 03/2014
1	Uridine Diphosphate (UDP)IBA 11/2013
1	sialic acid transport proteinsIBA 08/2013
1	Dystroglycans (Dystroglycan)IBA 03/2013
1	Aminobutyrates (Aminobutyric Acid)IBA 02/2013
1	gamma-Aminobutyric Acid (GABA)IBA 02/2013
1	Biomarkers (Surrogate Marker)IBA 09/2012
1	nephrinIBA 08/2012
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 03/2010
1	Glucose-6-Phosphatase (Glucose 6 Phosphatase)IBA 01/2009
1	SialyltransferasesIBA 11/2008
1	endo-alpha-sialidaseIBA 04/2008
1	Virulence Factors (Pathogenicity Factors)IBA 09/2007
1	DNA (Deoxyribonucleic Acid)IBA 08/2007
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 08/2003

Therapy/Procedure

2	Therapeutics 01/2017 - 07/2015
1	Intranasal Administration 01/2023
1	Oncolytic Virotherapy 01/2019
1	Immunotherapy 01/2019