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Tianyan Gao Selected Research

Mechanistic Target of Rapamycin Complex 2

5/2011mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
12/2009Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer.

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Tianyan Gao Research Topics

Disease

32Neoplasms (Cancer)
03/2024 - 04/2005
14Colorectal Neoplasms (Colorectal Cancer)
10/2021 - 08/2009
9Colonic Neoplasms (Colon Cancer)
10/2023 - 02/2011
7Carcinogenesis
03/2024 - 12/2009
6Neoplasm Metastasis (Metastasis)
11/2019 - 05/2011
3Obesity
01/2021 - 01/2016
3Inflammation (Inflammations)
01/2020 - 10/2015
3Colitis
12/2018 - 10/2015
3Starvation
01/2017 - 02/2011
2Triple Negative Breast Neoplasms
11/2019 - 10/2018
2Hypoxia (Hypoxemia)
10/2018 - 11/2013
1Prostatic Neoplasms (Prostate Cancer)
01/2021
1Dysbiosis
01/2020
1Breast Neoplasms (Breast Cancer)
10/2018
1Kidney Neoplasms (Kidney Cancer)
01/2018
1Colitis-Associated Neoplasms
02/2016
1Ulcer
02/2016
1Pancreatic Neoplasms (Pancreatic Cancer)
02/2016
1Sarcoma (Soft Tissue Sarcoma)
09/2014

Drug/Important Bio-Agent (IBA)

8Fatty Acids (Saturated Fatty Acids)IBA
10/2022 - 08/2015
8Proteins (Proteins, Gene)FDA Link
10/2021 - 11/2007
6Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
10/2021 - 04/2005
5EnzymesIBA
10/2020 - 06/2014
5Calcibiotic Root Canal SealerIBA
08/2015 - 12/2009
4Phosphotransferases (Kinase)IBA
10/2021 - 05/2011
4CateninsIBA
10/2020 - 02/2016
4Fatty Acid Synthases (Fatty Acid Synthase)IBA
01/2019 - 06/2014
4Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2017 - 04/2005
4Leucine-Rich Repeat ProteinsIBA
01/2017 - 04/2005
4Sirolimus (Rapamycin)FDA Link
09/2012 - 12/2009
3NeurotensinIBA
01/2021 - 01/2016
3Glucose (Dextrose)FDA LinkGeneric
10/2019 - 02/2011
3LipidsIBA
05/2018 - 08/2015
3Messenger RNA (mRNA)IBA
01/2018 - 08/2009
3TOR Serine-Threonine KinasesIBA
08/2013 - 12/2009
2Cadherins (E-Cadherin)IBA
01/2021 - 01/2018
2Adenosine Triphosphatases (ATPase)IBA
01/2021 - 01/2018
2Small Interfering RNA (siRNA)IBA
11/2019 - 08/2012
2IntegrinsIBA
11/2019 - 02/2016
2TVB-3664IBA
01/2019 - 05/2018
2Protein Isoforms (Isoforms)IBA
11/2013 - 02/2011
2Amino AcidsFDA Link
08/2013 - 02/2011
2Mechanistic Target of Rapamycin Complex 1IBA
05/2011 - 12/2009
2Mechanistic Target of Rapamycin Complex 2IBA
05/2011 - 12/2009
1ArsenicIBA
03/2024
1GlycogenIBA
10/2023
1villinIBA
10/2023
1quinolineIBA
10/2021
1BI 2536IBA
10/2021
1QuinolinesIBA
10/2021
1indoleIBA
10/2021
1Adenosine Monophosphate (AMP)IBA
10/2021
1Bile Acids and Salts (Bile Acids)IBA
01/2021
1Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA
10/2020
1Class 2 Receptor-Like Protein Tyrosine PhosphatasesIBA
10/2020
1Hormones (Hormone)IBA
01/2020
1DefensinsIBA
01/2020
1Transcription Factors (Transcription Factor)IBA
10/2019
1Adenosine Triphosphate (ATP)IBA
10/2019
1Mitochondrial DNA (mtDNA)IBA
10/2019
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
01/2019
1SphingolipidsIBA
01/2019
1Fingolimod Hydrochloride (FTY720)FDA Link
01/2019
1sphingosine kinaseIBA
01/2019
1GelatinIBA
01/2019
1SphingosineIBA
01/2019
1dihydrosphingosine 1-phosphateIBA
01/2019
1Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
10/2018
1CollagenIBA
10/2018
1Ketoglutaric Acids (Ketoglutaric Acid)IBA
10/2018
1Proline (L-Proline)FDA Link
10/2018
1Reactive Oxygen Species (Oxygen Radicals)IBA
10/2018
1Succinic Acid (Succinate)IBA
10/2018
1Phospholipids (Phosphatides)FDA LinkGeneric
05/2018
1Adenine NucleotidesIBA
05/2018
1CDw17 antigen (lactosylceramide)IBA
05/2018
1SphingomyelinsIBA
05/2018
1Lactic Acid (Lactate)FDA LinkGeneric
01/2018
1SuspensionsIBA
01/2018
1src-Family KinasesIBA
01/2018
1Nonesterified Fatty Acids (NEFA)IBA
01/2017
1HexokinaseIBA
01/2017
1Dextrans (Dextran)FDA Link
02/2016
1AzoxymethaneIBA
02/2016
1sodium sulfate (sodium bisulfate)FDA LinkGeneric
02/2016
1Insulin (Novolin)FDA Link
01/2016
1Peptides (Polypeptides)IBA
01/2016
1Proteasome InhibitorsIBA
10/2015
1Proteasome Endopeptidase Complex (Proteasome)IBA
10/2015
1Growth Factor ReceptorsIBA
09/2014
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
09/2014
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
09/2014
1matrigelIBA
06/2014
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2014
1Biomarkers (Surrogate Marker)IBA
11/2013
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
09/2012
1Sorafenib (BAY 43-9006)FDA Link
09/2012

Therapy/Procedure

3Drug Therapy (Chemotherapy)
10/2021 - 11/2013
1Immunotherapy
10/2021
1Precision Medicine
05/2018