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Bradley S Galer Selected Research

Myoclonic Epilepsies (Myoclonic Encephalopathy)

10/2023Fenfluramine in the treatment of Dravet syndrome: Results of a third randomized, placebo-controlled clinical trial.
1/2023Fenfluramine treatment is associated with improvement in everyday executive function in preschool-aged children (<5 years) with Dravet syndrome: A critical period for early neurodevelopment.
7/2022Long-term cardiovascular safety of fenfluramine in patients with Dravet syndrome treated for up to 3 years: Findings from serial echocardiographic assessments.
1/2022Fenfluramine treatment for dravet syndrome: Real-world benefits on quality of life from the caregiver perspective.
1/2022Fenfluramine significantly reduces day-to-day seizure burden by increasing number of seizure-free days and time between seizures in patients with Dravet syndrome: A time-to-event analysis.
12/2021Impact of fenfluramine on the expected SUDEP mortality rates in patients with Dravet syndrome.
8/2021An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies.
1/2021Treatment with fenfluramine in patients with Dravet syndrome has no long-term effects on weight and growth.
1/2021Improved everyday executive functioning following profound reduction in seizure frequency with fenfluramine: Analysis from a phase 3 long-term extension study in children/young adults with Dravet syndrome.
11/2020Cardiovascular safety of fenfluramine in the treatment of Dravet syndrome: Analysis of an ongoing long-term open-label safety extension study.
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Bradley S Galer Research Topics

Disease

21Pain (Aches)
12/2015 - 03/2003
14Myoclonic Epilepsies (Myoclonic Encephalopathy)
10/2023 - 10/2018
11Neuralgia (Stump Neuralgia)
04/2013 - 09/2002
8Low Back Pain (Lumbago)
12/2015 - 03/2003
7Seizures (Absence Seizure)
10/2023 - 12/2019
5Lennox Gastaut Syndrome
01/2023 - 10/2018
4Chronic Pain
09/2015 - 03/2003
4Osteoarthritis
03/2006 - 01/2004
4Postherpetic Neuralgia
01/2004 - 09/2002
3Sleepiness
10/2023 - 03/2006
2Fever (Fevers)
10/2023 - 01/2020
2Sudden Unexpected Death in Epilepsy
01/2023 - 12/2021
2Fatigue
01/2020 - 12/2019
2Nausea
09/2015 - 03/2006
2Vomiting
09/2015 - 03/2006
2Constipation
09/2015 - 03/2006
2Shoulder Impingement Syndrome
07/2015 - 04/2015
2Knee Osteoarthritis
04/2011 - 07/2008
1Epilepsy (Aura)
01/2021
1Diarrhea
01/2020
1Heart Valve Diseases (Valvular Heart Disease)
12/2019
1Lethargy
12/2019
1Reflex Epilepsy (Photosensitive Epilepsy)
12/2019
1Pulmonary Arterial Hypertension
12/2019
1Back Pain (Backache)
09/2015
1Arthralgia (Joint Pain)
09/2015
1Tendinopathy (Tendonitis)
01/2013
1Peripheral Nervous System Diseases (PNS Diseases)
10/2012
1Carpal Tunnel Syndrome
11/2006
1Headache (Headaches)
03/2006
1Hip Osteoarthritis (Coxarthrosis)
03/2006
1Arthritis (Polyarthritis)
03/2006
1Dizziness (Lightheadedness)
03/2006
1Pruritus (Itching)
03/2006
1Hyperalgesia
01/2004
1Diabetic Neuropathies (Diabetic Neuropathy)
01/2004
1Acute Pain
03/2003
1Wounds and Injuries (Trauma)
03/2003
1Postoperative Pain
03/2003

Drug/Important Bio-Agent (IBA)

16FenfluramineIBA
10/2023 - 10/2018
14Lidocaine (Xylocaine)FDA LinkGeneric
07/2015 - 09/2002
12Analgesics (Analgesic Drugs)IBA
10/2012 - 02/2003
7Opioid Analgesics (Opioids)IBA
12/2015 - 03/2003
3stiripentolIBA
10/2023 - 01/2019
3Anticonvulsants (Antiepileptic Drugs)IBA
01/2020 - 01/2019
3Tetracaine (Amethocaine)FDA LinkGeneric
07/2015 - 01/2013
2Hydrocodone (Dihydrocodeinone)FDA LinkGeneric
12/2015 - 09/2015
2Adrenal Cortex Hormones (Corticosteroids)IBA
07/2015 - 04/2015
2Pregabalin (Lyrica)FDA Link
04/2013 - 10/2012
2Oxymorphone (Numorphan)FDA LinkGeneric
02/2009 - 03/2006
2Gabapentin (Neurontin)FDA LinkGeneric
01/2004 - 11/2003
2Tramadol (K315)FDA LinkGeneric
11/2003 - 03/2003
2Acetaminophen (Paracetamol)FDA LinkGeneric
03/2003 - 03/2003
2Oxycodone (Oxycontin)FDA LinkGeneric
03/2003 - 03/2003
2oxycodone-acetaminophen (Percocet)FDA LinkGeneric
03/2003 - 03/2003
1Blood Glucose (Blood Sugar)IBA
10/2023
1Serotonin (5 Hydroxytryptamine)IBA
08/2021
1Sigma-1 ReceptorIBA
08/2021
1Valproic Acid (Depakote)FDA LinkGeneric
01/2019
1Clobazam (HR 376)IBA
01/2019
1SolutionsIBA
10/2018
14-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA
09/2015
1Triamcinolone (Aristocort)FDA Link
04/2015
1Glutamic Acid (Glutamate)FDA Link
01/2013
1Sodium Channels (Sodium Channel)IBA
01/2013
1SteroidsIBA
11/2006
1Non-Narcotic Analgesics (Analgesics, Non Narcotic)IBA
03/2006
1Dextromethorphan (Racemethorphan)FDA LinkGeneric
06/2005
1EN 3231IBA
06/2005
1Morphine (MS Contin)FDA LinkGeneric
06/2005
1Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA
11/2003
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
03/2003
1LidodermFDA Link
02/2003

Therapy/Procedure

3Aftercare (After-Treatment)
01/2022 - 11/2006
3Therapeutics
09/2015 - 01/2004
2Injections
07/2015 - 04/2015
2Analgesia
03/2006 - 06/2005
1Oral Surgery (Maxillofacial Surgery)
03/2003