Keiko Furukawa Selected Research

Enzymes

12/2021	Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins.
5/2019	New era of research on cancer-associated glycosphingolipids.
1/2019	Loss of Enzyme Activity in Mutated B4GALNT1 Gene Products in Patients with Hereditary Spastic Paraplegia Results in Relatively Mild Neurological Disorders: Similarity with Phenotypes of B4galnt1 Knockout Mice.
1/2018	ASC amino acid transporter 2, defined by enzyme-mediated activation of radical sources, enhances malignancy of GD2-positive small-cell lung cancer.
1/2016	Neogenin, Defined as a GD3-associated Molecule by Enzyme-mediated Activation of Radical Sources, Confers Malignant Properties via Intracytoplasmic Domain in Melanoma Cells.
3/2014	UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6.
3/2007	Identification and expression of a sialyltransferase responsible for the synthesis of disialylgalactosylgloboside in normal and malignant kidney cells: downregulation of ST6GalNAc VI in renal cancers.

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Keiko Furukawa Research Topics

Disease

28	Neoplasms (Cancer) 01/2023 - 01/2003
24	Melanoma (Melanoma, Malignant) 01/2023 - 08/2005
10	Inflammation (Inflammations) 03/2020 - 12/2009
7	Glioma (Gliomas) 09/2023 - 06/2015
7	Lung Neoplasms (Lung Cancer) 10/2016 - 01/2003
6	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2018 - 08/2005
5	Neoplasm Metastasis (Metastasis) 01/2016 - 01/2003
4	Alzheimer Disease (Alzheimer's Disease) 01/2018 - 12/2009
4	Guillain-Barre Syndrome 05/2007 - 09/2002
3	Hereditary Spastic Paraplegia 01/2022 - 01/2019
3	Nervous System Diseases (Neurological Disorders) 08/2020 - 01/2019
3	Kidney Neoplasms (Kidney Cancer) 04/2020 - 03/2007
2	Infections 09/2023 - 09/2002
2	autosomal recessive Spastic paraplegia 26 01/2023 - 01/2022
2	Squamous Cell Carcinoma of Head and Neck 04/2021 - 08/2013
2	Pain (Aches) 01/2020 - 10/2005
2	Colonic Neoplasms (Colon Cancer) 12/2019 - 06/2003
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2018 - 04/2016
2	Osteosarcoma (Osteogenic Sarcoma) 12/2012 - 09/2012
2	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2012 - 09/2011
2	Peripheral Nervous System Diseases (PNS Diseases) 03/2009 - 01/2006
1	Brain Neoplasms (Brain Tumor) 01/2024
1	Human Influenza (Influenza) 09/2023
1	Virus Diseases (Viral Diseases) 09/2023
1	Epilepsy (Aura) 09/2023
1	Insulin Resistance 01/2023
1	Astrocytoma (Pilocytic Astrocytoma) 01/2023
1	Seizures (Absence Seizure) 06/2022
1	Rare Diseases (Rare Disease) 01/2022
1	Aphasia (Dysphasia) 07/2021
1	Sleepiness 07/2021
1	Neuroblastoma 04/2018
1	Dementia (Dementias) 09/2016
1	Pathologic Processes 01/2016

Drug/Important Bio-Agent (IBA)

40	GangliosidesIBA 01/2023 - 09/2002
19	GD3 ganglioside (GD(3))IBA 01/2023 - 08/2005
11	GlycolipidsIBA 01/2022 - 08/2008
10	AntigensIBA 01/2022 - 08/2008
9	GlycosphingolipidsIBA 05/2019 - 01/2005
8	LipidsIBA 09/2023 - 06/2006
8	N-Acetylneuraminic Acid (Sialic Acid)IBA 12/2019 - 01/2005
7	EnzymesIBA 12/2021 - 03/2007
7	Complement System Proteins (Complement)IBA 03/2020 - 12/2009
7	Complementary DNA (cDNA)IBA 12/2019 - 01/2003
6	AntibodiesIBA 09/2023 - 07/2004
6	PaxillinIBA 08/2016 - 08/2005
5	Messenger RNA (mRNA)IBA 01/2023 - 03/2002
5	IntegrinsIBA 12/2021 - 08/2005
4	(N- acetylneuraminyl)- galactosylglucosylceramide N-acetylgalactosaminyltransferaseIBA 01/2023 - 01/2003
4	CarbohydratesIBA 01/2022 - 01/2003
4	Proteins (Proteins, Gene)FDA Link 10/2017 - 01/2011
4	Monoclonal AntibodiesIBA 04/2016 - 08/2005
3	GD2 gangliosideIBA 01/2023 - 01/2018
3	CytokinesIBA 08/2021 - 12/2009
3	GlycosyltransferasesIBA 08/2020 - 03/2014
3	Tn antigenIBA 10/2016 - 03/2012
3	Focal Adhesion Protein-Tyrosine KinasesIBA 08/2016 - 03/2008
3	AutoantibodiesIBA 03/2009 - 09/2002
3	Tyrosine (L-Tyrosine)FDA Link 08/2008 - 11/2006
2	Anticonvulsants (Antiepileptic Drugs)IBA 06/2022 - 07/2021
2	Proto-Oncogene Proteins c-sis (Platelet Derived Growth Factor B)IBA 09/2021 - 06/2015
2	src-Family KinasesIBA 09/2021 - 05/2011
2	A-Form DNA (A-DNA)IBA 09/2021 - 08/2013
2	DNA (Deoxyribonucleic Acid)IBA 08/2021 - 08/2006
2	LectinsIBA 12/2019 - 12/2013
2	LigandsIBA 12/2019 - 03/2013
2	Tumor Biomarkers (Tumor Markers)IBA 05/2019 - 08/2008
2	Small Interfering RNA (siRNA)IBA 08/2016 - 03/2008
2	UDP-galactose-lactosylceramide alpha 1-4-galactosyltransferaseIBA 04/2016 - 03/2002
2	Syndecan-1 (Syndecan 1)IBA 08/2013 - 03/2012
2	Caveolin 1IBA 04/2007 - 08/2006
2	GalNAc sialyltransferase VIIBA 03/2007 - 06/2003
2	SialyltransferasesIBA 03/2007 - 06/2003
2	LipopolysaccharidesIBA 07/2004 - 09/2002
1	EpitopesIBA 09/2023
1	Vaccine AdjuvantsIBA 09/2023
1	Levetiracetam (Keppra)FDA LinkGeneric 09/2023
1	Decitabine FDA Link 01/2023
1	Insulin (Novolin)FDA Link 01/2023
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2022
1	Matrix Metalloproteinases (MMPs)IBA 09/2021
1	ChemokinesIBA 08/2021
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 08/2021
1	Epidermal Growth Factor (EGF)IBA 04/2021
1	SugarsIBA 01/2021
1	Sialic AcidsIBA 01/2021
1	AminoglycosidesIBA 08/2020
1	Indicators and Reagents (Reagents)IBA 08/2020
1	Nonsense Codon (Nonsense Mutation)IBA 08/2020
1	Sialic Acid Binding Immunoglobulin-like LectinsIBA 12/2019
1	Recombinant ProteinsIBA 12/2019
1	Amino Acid Transport Systems (Amino Acid Transporter)IBA 01/2018
1	Amyloid (Amyloid Fibrils)IBA 09/2016
1	Peptides (Polypeptides)IBA 09/2016
1	atelocollagenIBA 08/2016
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2016

Therapy/Procedure

7	Therapeutics 05/2019 - 01/2006
3	Craniotomy 01/2024 - 01/2020
3	Immunotherapy 01/2022 - 08/2008
1	Anesthesia 07/2021