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Ilya Frolov Selected Research

Proteins (Proteins, Gene)

1/2019Novel Mutations in nsP2 Abolish Chikungunya Virus-Induced Transcriptional Shutoff and Make the Virus Less Cytopathic without Affecting Its Replication Rates.
2/2017A chikungunya fever vaccine utilizing an insect-specific virus platform.
1/2016Both RIG-I and MDA5 detect alphavirus replication in concentration-dependent mode.
2/2013Pseudoinfectious Venezuelan equine encephalitis virus: a new means of alphavirus attenuation.
9/2008Chimeric alphavirus vaccine candidates for chikungunya.
4/2006Formation of nsP3-specific protein complexes during Sindbis virus replication.
3/2006Replication and clearance of Venezuelan equine encephalitis virus from the brains of animals vaccinated with chimeric SIN/VEE viruses.
11/2002Roles of nonstructural protein nsP2 and Alpha/Beta interferons in determining the outcome of Sindbis virus infection.

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Ilya Frolov Research Topics

Disease

18Infections
11/2023 - 08/2005
7Alphavirus Infections
01/2019 - 11/2002
5Venezuelan Equine Encephalomyelitis
01/2018 - 09/2007
4Viremia
01/2020 - 08/2005
2Arthritis (Polyarthritis)
01/2021 - 09/2008
2Chikungunya Fever
02/2017 - 07/2011
2Eastern Equine Encephalomyelitis
03/2013 - 10/2007
1COVID-19
10/2022
1Meningoencephalitis
01/2020
1Porcine Reproductive and Respiratory Syndrome (PRRS)
01/2016
1Type I Syndactyly
01/2016
1Virus Diseases (Viral Diseases)
02/2013
1Vector Borne Diseases
07/2011
1Persistent Infection
10/2010
1Encephalitis (Encephalitis, Rasmussen)
01/2008
1Japanese Encephalitis
01/2008
1Dengue (Dengue Fever)
01/2008
1Flavivirus Infections
08/2006
1Diarrhea
03/2005
1Superinfection
03/2005
1Neoplasms (Cancer)
10/2004
1Glioma (Gliomas)
10/2004

Drug/Important Bio-Agent (IBA)

18VaccinesIBA
01/2021 - 03/2006
8Proteins (Proteins, Gene)FDA Link
01/2019 - 11/2002
5Capsid Proteins (Capsid Protein)IBA
01/2020 - 10/2010
5Antiviral Agents (Antivirals)IBA
01/2016 - 08/2005
3RNA (Ribonucleic Acid)IBA
07/2014 - 03/2005
3Glycoproteins (Glycoprotein)IBA
09/2007 - 10/2004
2EnzymesIBA
01/2015 - 07/2014
2AntigensIBA
01/2015 - 02/2013
2Viral RNAIBA
04/2013 - 03/2005
2InterferonsIBA
05/2012 - 11/2002
1sodium arsenite (sodium metaarsenite)IBA
11/2023
1SARS-CoV-2 spike proteinIBA
10/2022
1FurinIBA
10/2022
1mRNA VaccinesIBA
10/2022
1Ribavirin (Virazole)FDA LinkGeneric
01/2018
1Complementary DNA (cDNA)IBA
02/2017
1Pattern Recognition ReceptorsIBA
01/2016
1ImmunosorbentsIBA
01/2015
1Viral Structural Proteins (VP(1))IBA
02/2013
1Attenuated VaccinesIBA
09/2008
1Interferon-betaIBA
07/2008
1Neutralizing AntibodiesIBA
10/2007
1Laminin ReceptorsIBA
10/2004
1beta-Galactosidase (Lactaid)IBA
10/2004
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
10/2004

Therapy/Procedure

1Therapeutics
01/2018