Michael L Freeman Selected Research

Neutralizing Antibodies

1/2017	Inhibition of TGF-β with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.
2/2010	Differential impact of ageing on cellular and humoral immunity to a persistent murine gamma-herpesvirus.
5/2007	Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.

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Michael L Freeman Research Topics

Disease

22	Neoplasms (Cancer) 01/2023 - 01/2003
17	Infections 12/2023 - 02/2010
14	Inflammation (Inflammations) 02/2024 - 03/2010
10	HIV Infections (HIV Infection) 02/2024 - 01/2003
4	Cardiovascular Diseases (Cardiovascular Disease) 08/2023 - 12/2016
3	Atherosclerotic Plaque (Atheroma) 12/2023 - 01/2020
3	Viremia 01/2022 - 01/2021
3	Fibrosis (Cirrhosis) 01/2022 - 02/2005
3	Breast Neoplasms (Breast Cancer) 01/2019 - 05/2007
3	Latent Infection 04/2012 - 03/2011
2	Atherosclerosis 12/2023 - 01/2020
2	COVID-19 01/2023 - 12/2021
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2022 - 01/2016
2	Lymphopenia (Lymphocytopenia) 01/2022 - 12/2019
2	Gastroparesis 05/2021 - 08/2011
2	Coinfection 01/2021 - 01/2020
2	Virus Diseases (Viral Diseases) 01/2020 - 02/2012
2	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 01/2014
2	Disease Progression 01/2016 - 01/2016
2	Persistent Infection 07/2014 - 12/2011
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2014 - 03/2010
2	Neoplasm Metastasis (Metastasis) 12/2013 - 05/2007
2	Pneumonia (Pneumonitis) 02/2013 - 03/2010
2	Hyperthermia 12/2007 - 01/2007
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2023
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2023
1	Pulmonary Arterial Hypertension 01/2023
1	Hyperglycemia 01/2022
1	Radiation Fibrosis Syndrome (Radiation Fibrosis) 01/2022
1	Obesity 05/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021
1	Type 2 Diabetes Mellitus (MODY) 10/2020
1	Colorectal Neoplasms (Colorectal Cancer) 01/2019

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 12/2021 - 07/2002
7	CytokinesIBA 12/2023 - 03/2010
5	Biomarkers (Surrogate Marker)IBA 08/2023 - 09/2006
4	VaccinesIBA 02/2023 - 03/2010
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 02/2013
4	EnzymesIBA 05/2021 - 12/2005
4	EpitopesIBA 12/2014 - 03/2010
3	Neutralizing AntibodiesIBA 01/2017 - 05/2007
3	Oxidants (Oxidizing Agents)IBA 01/2016 - 03/2010
3	Antiviral Agents (Antivirals)IBA 07/2014 - 03/2010
3	Transcription Factors (Transcription Factor)IBA 01/2014 - 12/2005
3	AntioxidantsIBA 08/2011 - 12/2005
2	CD58 Antigens (LFA-3)IBA 12/2023 - 01/2020
2	LipidsIBA 01/2023 - 05/2016
2	NucleophosminIBA 01/2023 - 11/2015
2	Interleukin-6 (Interleukin 6)IBA 01/2023 - 01/2021
2	Bleomycin (Blenoxane)FDA LinkGeneric 01/2022 - 01/2019
2	Arachidonic Acid (Vitamin F)IBA 01/2022 - 01/2016
2	Interleukin-15 (Interleukin 15)IBA 01/2020 - 01/2016
2	Androgen Receptors (Androgen Receptor)IBA 01/2019 - 01/2014
2	AndrogensIBA 01/2019 - 01/2014
2	Prostaglandin D2IBA 12/2013 - 10/2007
2	TriterpenesIBA 02/2013 - 03/2010
2	NADPH Oxidases (NAD(P)H oxidase)IBA 02/2013 - 03/2010
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 05/2007 - 02/2005
2	Transforming Growth Factor beta (TGF-beta)IBA 05/2007 - 02/2005
1	Lipoprotein(a)IBA 02/2024
1	Granzymes (Granzyme)IBA 12/2023
1	Macrophage Colony-Stimulating FactorIBA 09/2023
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 09/2023
1	SARS-CoV-2 spike proteinIBA 02/2023
1	BNT162 VaccineIBA 02/2023
1	Messenger RNA (mRNA)IBA 02/2023
1	mRNA VaccinesIBA 02/2023
1	Hormones (Hormone)IBA 01/2023
1	tocilizumab (atlizumab)FDA Link 01/2023
1	Leptin ReceptorsIBA 01/2023
1	LeptinIBA 01/2023
1	Metformin (Glucophage)FDA LinkGeneric 01/2023
1	F2-Isoprostanes (F2 Isoprostanes)IBA 01/2022
1	LigandsIBA 01/2022
1	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 01/2022
1	PerforinIBA 01/2022
1	Fingolimod Hydrochloride (FTY720)FDA Link 01/2022
1	ProstaglandinsIBA 01/2022
1	Streptozocin (Streptozotocin)FDA Link 01/2022
1	ifetrobanIBA 01/2022
1	ThromboxanesIBA 01/2022
1	BradykininIBA 12/2021
1	Cholinergic Agents (Cholinergics)IBA 05/2021
1	Adrenergic Agents (Adrenergic Drugs)IBA 05/2021
1	CurcuminIBA 05/2021
1	cinnamaldehyde (cinnamic aldehyde)FDA Link 05/2021
1	Soluble Guanylyl CyclaseIBA 05/2021
1	Glutathione Disulfide (GSSG)FDA LinkGeneric 05/2021
1	Lipopolysaccharide ReceptorsIBA 01/2021
1	Adenosine Monophosphate (AMP)IBA 12/2020
1	Adenosine (Adenocard)FDA LinkGeneric 12/2020
1	Estrogens (Estrogen)FDA Link 10/2020
1	NitratesIBA 10/2020
1	SB 216763IBA 10/2020

Therapy/Procedure

11	Therapeutics 01/2021 - 05/2007
8	Radiotherapy 01/2021 - 01/2007
6	Art Therapy 08/2023 - 02/2016
2	Castration 01/2019 - 01/2014
1	Home Nursing (Nursing, Home) 02/2023
1	Highly Active Antiretroviral Therapy (HAART) 01/2022