Liberty François-Moutal Selected Research

Voltage-Gated Sodium Channels

10/2018	Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain.
1/2018	Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels.

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Liberty François-Moutal Research Topics

Disease

10	Pain (Aches) 05/2024 - 07/2015
5	Hyperalgesia 01/2023 - 12/2017
4	Neuralgia (Stump Neuralgia) 01/2023 - 01/2018
4	Chronic Pain 12/2019 - 01/2018
3	Hypersensitivity (Allergy) 05/2024 - 07/2015
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2019
2	Peripheral Nervous System Diseases (PNS Diseases) 01/2023 - 01/2019
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 01/2019
2	Postoperative Pain 01/2018 - 07/2015
1	Thymoma (Thymic Carcinoma) 05/2024
1	Neoplasms (Cancer) 05/2024
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 05/2024
1	Alzheimer Disease (Alzheimer's Disease) 12/2019
1	Neurofibromatoses (Neurofibromatosis) 12/2017
1	Surgical Wound 07/2015
1	Rupture 01/2013
1	Barth Syndrome 01/2013

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 05/2024 - 07/2015
5	Semaphorin-3AIBA 05/2024 - 12/2017
4	Peptides (Polypeptides)IBA 01/2023 - 07/2015
3	Ion Channels (Ion Channel)IBA 12/2019 - 12/2017
3	CalciumIBA 12/2019 - 01/2018
2	UbiquitinIBA 01/2023 - 10/2018
2	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2022 - 01/2019
2	SodiumIBA 11/2021 - 12/2019
2	Voltage-Gated Sodium ChannelsIBA 10/2018 - 01/2018
1	AntigensIBA 05/2024
1	AutoantibodiesIBA 05/2024
1	AutoantigensIBA 05/2024
1	Protein AggregatesIBA 01/2022
1	N-Type Calcium Channels (N-Type Calcium Channel)IBA 12/2019
1	Sodium Channels (Sodium Channel)IBA 12/2019
1	naringeninIBA 12/2019
1	maleic acid (maleate)IBA 12/2019
1	QuinazolinesIBA 01/2019
1	RNA (Ribonucleic Acid)IBA 01/2019
1	LigandsIBA 10/2018
1	Amino Acids FDA Link 01/2018
1	Glycoproteins (Glycoprotein)IBA 01/2018
1	EnzymesIBA 01/2018
1	Lacosamide FDA Link 12/2017
1	Neurofibromin 1 (Neurofibromin)IBA 12/2017
1	CarrageenanIBA 07/2015
1	Calcium Channels (Calcium Channel)IBA 07/2015
1	Cardiolipins (Cardiolipin)IBA 01/2013
1	Caspase 8 (Caspase-8)IBA 01/2013
1	laurdanIBA 01/2013

Therapy/Procedure

3	Therapeutics 11/2021 - 07/2015
2	Drug Therapy (Chemotherapy) 01/2023 - 01/2019
1	Ligation 01/2019