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Silke Frahm Selected Research

Prodrugs

5/2004Sulindac derivatives inhibit cell growth and induce apoptosis in primary cells from malignant peripheral nerve sheath tumors of NF1-patients.

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Silke Frahm Research Topics

Disease

7Neurofibrosarcoma (MPNST)
12/2008 - 05/2004
5Parkinson Disease (Parkinson's Disease)
03/2024 - 01/2017
4Synucleinopathies
03/2024 - 01/2017
4Tobacco Use Disorder (Nicotine Dependence)
12/2015 - 05/2011
4Neoplasms (Cancer)
04/2005 - 05/2004
2Neurodegenerative Diseases (Neurodegenerative Disease)
03/2024 - 01/2017
2Dementia (Dementias)
01/2022 - 02/2018
2Neurofibromatosis 1 (Neurofibromatosis Type I)
12/2008 - 05/2004
1Motor Disorders
01/2019
1Pain (Aches)
06/2015
1Arthritis (Polyarthritis)
06/2015
1Inflammation (Inflammations)
06/2015
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2014
1Herpes Simplex
12/2008
1Neoplasm Metastasis (Metastasis)
03/2006
1Prostatic Neoplasms (Prostate Cancer)
04/2005
1Nerve Sheath Neoplasms (Nerve Sheath Neoplasm)
07/2004

Drug/Important Bio-Agent (IBA)

3alpha-SynucleinIBA
03/2024 - 02/2018
3Proteins (Proteins, Gene)FDA Link
01/2017 - 03/2006
2hydromethylthionineIBA
01/2022 - 01/2017
2SynucleinsIBA
01/2019 - 01/2017
2Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2014 - 05/2011
2Neurofibromin 1 (Neurofibromin)IBA
12/2008 - 07/2004
1Acetylcholine (Acetylcholine Chloride)FDA Link
12/2015
1Glutamic Acid (Glutamate)FDA Link
12/2015
1Analgesics (Analgesic Drugs)IBA
06/2015
1AntigensIBA
06/2015
1CalciumIBA
06/2015
1CollagenIBA
06/2015
1Conotoxins (Conotoxin)IBA
06/2015
1Neurotransmitter Agents (Neurotransmitter)IBA
06/2015
1ziconotide (Prialt)FDA Link
06/2015
1NicotineFDA Link
01/2014
1Cholinergic ReceptorsIBA
10/2013
1raf KinasesIBA
12/2008
1Viral ProteinsIBA
12/2008
1ErbB Receptors (EGF Receptor)IBA
03/2006
1OligonucleotidesIBA
03/2006
1Biomarkers (Surrogate Marker)IBA
03/2006
1Cyclin-Dependent Kinase Inhibitor p16IBA
03/2006
1Tumor Suppressor Protein p14ARF (p14ARF)IBA
03/2006
1Small Interfering RNA (siRNA)IBA
03/2006
1S100 Calcium Binding Protein beta SubunitIBA
03/2006
1GelsolinIBA
04/2005
1Histone Deacetylase InhibitorsIBA
04/2005
1Phosphotransferases (Kinase)IBA
04/2005
1Histone Deacetylases (Histone Deacetylase)IBA
04/2005
1romidepsin (FK228)FDA Link
04/2005
1Arachidonic Acid (Vitamin F)IBA
03/2005
1Fatty Acids (Saturated Fatty Acids)IBA
03/2005
1Docosahexaenoic AcidsIBA
03/2005
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2005
1Omega-6 Fatty Acids (Omega 6 Fatty Acids)IBA
03/2005
1antineoplaston A10 (A 10)IBA
07/2004
1Complementary DNA (cDNA)IBA
07/2004
1ProdrugsIBA
05/2004
1Antineoplastic Agents (Antineoplastics)IBA
05/2004
1sulindac sulfideIBA
05/2004
1sulindac sulfone (exisulind)IBA
05/2004
1Guanosine Triphosphate (GTP)IBA
05/2004
1Sulindac (Copal)FDA LinkGeneric
05/2004

Therapy/Procedure

5Therapeutics
03/2024 - 06/2004
1Drug Therapy (Chemotherapy)
03/2006