Michael G Fradley Selected Research

Heart Failure

11/2023	Impact of Atrial Fibrillation on Heart Failure in Patients Treated With Anthracycline Chemotherapy.
10/2023	The Association of Metformin With Heart Failure in Patients With Diabetes Mellitus Receiving Anthracycline Chemotherapy.
1/2023	Racial and Ethnic Differences in Cardiac Surveillance Evaluation of Patients Treated With Anthracycline-Based Chemotherapy.
1/2023	Heart Failure in Patients With Cancer Treated With Anthracyclines-Revisiting the Foundation of Cardio-Oncology.
1/2023	Adverse Cardiovascular Events Associated With Cyclin-Dependent Kinase 4/6 Inhibitors in Patients With Metastatic Breast Cancer.
1/2023	Whole-Exome sequencing analysis identified TMSB10/TRABD2A locus to be associated with carfilzomib-related cardiotoxicity among patients with multiple myeloma.
2/2021	Cardiovascular Toxicity and Mortality Associated With Adoptive Cell Therapy and Tumor-infiltrating Lymphocytes for Advanced Stage Melanoma.
1/2021	Lactate Dehydrogenase B and Pyruvate Oxidation Pathway Associated With Carfilzomib-Related Cardiotoxicity in Multiple Myeloma Patients: Result of a Multi-Omics Integrative Analysis.
1/2021	Cardiovascular Events in Men with Prostate Cancer Receiving Hormone Therapy: An Analysis of the FDA Adverse Event Reporting System (FAERS).
1/2021	Impact of Global Budget Payments on Cardiovascular Care in Maryland: An Interrupted Time Series Analysis.

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Michael G Fradley Research Topics

Disease

41	Neoplasms (Cancer) 10/2023 - 01/2013
23	Cardiotoxicity 10/2023 - 01/2013
19	Heart Failure 11/2023 - 09/2012
12	Myocarditis (Carditis) 11/2022 - 01/2013
11	Cardiovascular Diseases (Cardiovascular Disease) 04/2023 - 06/2017
10	Atrial Fibrillation 11/2023 - 01/2014
10	Cardiomyopathies (Cardiomyopathy) 01/2023 - 01/2017
8	Hypertension (High Blood Pressure) 01/2023 - 05/2016
8	Multiple Myeloma 01/2023 - 01/2016
7	Heart Block 01/2021 - 01/2016
5	Breast Neoplasms (Breast Cancer) 01/2023 - 05/2021
5	Cardiogenic Shock 01/2021 - 01/2018
5	Heart Arrest (Cardiac Arrest) 01/2021 - 01/2013
4	Ischemic Stroke 01/2023 - 01/2019
4	Stroke (Strokes) 01/2021 - 01/2017
3	Melanoma (Melanoma, Malignant) 02/2022 - 01/2019
3	Hemorrhage 01/2021 - 01/2019
3	Cardiac Arrhythmias (Arrythmia) 11/2019 - 01/2013
2	Hematologic Neoplasms (Hematological Malignancy) 04/2023 - 03/2021
2	Embolic Stroke 01/2021 - 01/2019
2	Myocardial Infarction 01/2021 - 01/2012
2	Transient Ischemic Attack 01/2021 - 01/2019
2	Thrombocytopenia (Thrombopenia) 12/2020 - 01/2012
2	Dyspnea (Shortness of Breath) 09/2020 - 01/2018
1	Diabetes Mellitus 10/2023
1	Inflammation (Inflammations) 04/2023
1	Second Primary Neoplasms (Neoplasms, Second) 01/2022
1	Hypotension (Low Blood Pressure) 02/2021
1	Cerebral Hemorrhage 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2021
1	Prostatic Neoplasms (Prostate Cancer) 01/2021
1	Venous Thromboembolism 12/2020
1	Death (Near-Death Experience) 11/2020
1	Alveolar Soft Part Sarcoma 09/2020
1	Torsades de Pointes (Torsade de Pointes) 09/2020

Drug/Important Bio-Agent (IBA)

12	AnthracyclinesIBA 11/2023 - 01/2016
12	Immune Checkpoint InhibitorsIBA 11/2022 - 01/2018
9	Proteasome InhibitorsIBA 01/2023 - 01/2016
6	omega-Chloroacetophenone (Mace)IBA 01/2021 - 01/2018
5	Biomarkers (Surrogate Marker)IBA 04/2023 - 09/2012
5	carfilzomibIBA 01/2023 - 01/2018
4	Immunomodulating AgentsIBA 04/2022 - 01/2018
4	Warfarin (Coumadin)FDA LinkGeneric 01/2021 - 01/2019
4	Tyrosine Kinase InhibitorsIBA 12/2019 - 04/2017
3	Chimeric Antigen ReceptorsIBA 04/2023 - 12/2019
3	AnticoagulantsIBA 01/2023 - 01/2019
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 02/2022 - 11/2020
3	Antineoplastic Agents (Antineoplastics)IBA 03/2021 - 06/2017
3	TroponinIBA 02/2021 - 01/2019
3	apixabanIBA 01/2021 - 01/2019
2	Troponin IIBA 04/2023 - 01/2014
2	Hormones (Hormone)IBA 01/2023 - 01/2021
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2023 - 01/2019
2	Trastuzumab (Herceptin)FDA Link 01/2022 - 11/2020
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2020 - 05/2016
2	GadoliniumIBA 09/2020 - 01/2020
2	ibrutinibIBA 01/2019 - 01/2019
2	Bortezomib (Velcade)FDA Link 03/2018 - 01/2016
2	Lenalidomide (CC 5013)FDA Link 03/2018 - 01/2018
2	SteroidsIBA 03/2018 - 01/2018
1	Metformin (Glucophage)FDA LinkGeneric 10/2023
1	Interleukin-6 (Interleukin 6)IBA 04/2023
1	CytokinesIBA 04/2023
1	Interleukin-15 (Interleukin 15)IBA 04/2023
1	CreatinineIBA 04/2023
1	ErbB Receptors (EGF Receptor)IBA 01/2023
1	LipidsIBA 01/2023
1	methylamphotericin B (AME)IBA 01/2023
1	CholesterolIBA 01/2023
1	Cyclin-Dependent Kinase 4IBA 01/2023
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2023
1	InterferonsIBA 02/2022
1	vasectrin I (VS I)IBA 01/2022
1	Aryldialkylphosphatase (Paraoxonase)IBA 01/2022
1	arylesteraseIBA 01/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022
1	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 10/2021
1	NivolumabIBA 03/2021
1	lactate dehydrogenase 1 (LDH1)IBA 01/2021
1	abirateroneIBA 01/2021
1	Pyruvic Acid (Pyruvate)IBA 01/2021
1	Androgen Receptor AntagonistsIBA 01/2021
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2021
1	Steroid Synthesis InhibitorsIBA 01/2021
1	AndrogensIBA 11/2020
1	Phosphotransferases (Kinase)IBA 11/2020
1	pembrolizumabIBA 09/2020
1	Death Domain ReceptorsIBA 09/2020

Therapy/Procedure

38	Therapeutics 04/2023 - 01/2016
15	Drug Therapy (Chemotherapy) 11/2023 - 01/2016
6	Immunotherapy 04/2023 - 01/2019
2	Length of Stay 01/2022 - 01/2021
2	Percutaneous Coronary Intervention 01/2021 - 01/2019
2	Cardiac Resynchronization Therapy 01/2020 - 11/2019
2	Defibrillators (Defibrillator) 11/2019 - 01/2016
1	Stroke Rehabilitation 01/2023
1	Electric Countershock (Cardioversion) 01/2022
1	Cell- and Tissue-Based Therapy (Cell Therapy) 02/2021
1	Precision Medicine 01/2021
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2021