Jason Flannick Selected Research

Insulin Resistance

11/2022	Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans.
1/2018	Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.
1/2018	Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
1/2018	Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis.
1/2017	A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.

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Jason Flannick Research Topics

Disease

19	Type 2 Diabetes Mellitus (MODY) 07/2023 - 11/2013
5	Obesity 05/2023 - 01/2018
5	Insulin Resistance 11/2022 - 01/2017
2	Lipodystrophy 01/2019 - 01/2018
2	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2015 - 09/2012
1	Solitary Kidney 01/2023
1	Abdominal Obesity 01/2022
1	Atherosclerosis 01/2022
1	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2022
1	Hypertension (High Blood Pressure) 08/2021
1	Dyslipidemias (Dyslipidemia) 01/2021
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2018
1	Autistic Disorder (Autism) 01/2018
1	Bipolar Disorder (Manic Depressive Psychosis) 01/2018
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2018
1	Intellectual Disability (Idiocy) 01/2018
1	Schizophrenia (Dementia Praecox) 01/2018
1	Disease Progression 01/2018
1	Mental Disorders (Mental Disorder) 10/2017
1	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 10/2017
1	Neuroblastoma 10/2017
1	Mason-Type Diabetes 01/2017
1	Heart Failure 01/2015
1	Neoplasms (Cancer) 12/2014
1	Type 3 Maturity-Onset Diabetes of the Young 06/2014
1	Chronic Renal Insufficiency 02/2014
1	Infections 02/2014
1	Cardiovascular Diseases (Cardiovascular Disease) 02/2014
1	Rheumatoid Arthritis 01/2013
1	Microphthalmos 12/2011
1	Anophthalmos (Anophthalmia) 12/2011

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 07/2023 - 09/2012
5	Glucose (Dextrose)FDA LinkGeneric 11/2022 - 01/2015
5	ProdigyIBA 10/2022 - 01/2021
4	LipidsIBA 01/2022 - 01/2018
2	P-2 (P 2)IBA 05/2023 - 02/2014
2	Nonesterified Fatty Acids (NEFA)IBA 02/2023 - 01/2023
2	Insulin (Novolin)FDA Link 11/2022 - 01/2017
2	Apolipoprotein L1IBA 01/2022 - 02/2014
2	HDL CholesterolIBA 08/2021 - 01/2018
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2018
2	HDL LipoproteinsIBA 01/2018 - 02/2014
2	DNA (Deoxyribonucleic Acid)IBA 10/2017 - 06/2014
2	Transcription Factors (Transcription Factor)IBA 10/2017 - 12/2011
1	ChromatinIBA 01/2023
1	Chenodeoxycholic Acid (Chenix)FDA Link 11/2022
1	Bile Acids and Salts (Bile Acids)IBA 11/2022
1	Cholic AcidIBA 11/2022
1	Hemoglobins (Hemoglobin)IBA 11/2022
1	Steroid 12-alpha-Hydroxylase (CYP8B1)IBA 11/2022
1	Activins (Activin)IBA 01/2022
1	C-PeptideIBA 08/2021
1	Zinc Transporter 8IBA 11/2019
1	Taurine FDA Link 01/2018
1	Genetic Markers (Genetic Marker)IBA 01/2018
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2018
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 01/2018
1	NitrogenIBA 01/2018
1	Phenylalanine (L-Phenylalanine)FDA Link 01/2018
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 01/2018
1	Triglycerides (Triacylglycerol)IBA 01/2018
1	AngiopoietinsIBA 01/2018
1	AdiponectinIBA 01/2018
1	Islet Amyloid PolypeptideIBA 01/2018
1	Glutamic Acid (Glutamate)FDA Link 10/2017
1	Hepatocyte Nuclear FactorsIBA 01/2017
1	ConnectinIBA 01/2015
1	NucleotidesIBA 12/2014
1	Hepatocyte Nuclear Factor 1IBA 06/2014
1	LDL CholesterolIBA 02/2014
1	oxidized low density lipoproteinIBA 02/2014

Therapy/Procedure

1	Bariatric Surgery 01/2022