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H J Federoff Selected Research

Therapeutics

10/2001Dendritic cells transduced with HSV-1 amplicons expressing prostate-specific antigen generate antitumor immunity in mice.
9/2001A novel approach to cancer therapy using an oncolytic herpes virus to package amplicons containing cytokine genes.
5/2001Intravesical oncolytic viral therapy using attenuated, replication-competent herpes simplex viruses G207 and Nv1020 is effective in the treatment of bladder cancer in an orthotopic syngeneic model.
3/2000Discordance between expression and genome transfer titering of HSV amplicon vectors: recommendation for standardized enumeration.

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H J Federoff Research Topics

Disease

3Neoplasms (Cancer)
10/2001 - 03/2001
2Alzheimer Disease (Alzheimer's Disease)
07/2005 - 10/2001
1Infections
01/2008
1Tremor (Tremors)
05/2005
1Parkinson Disease (Parkinson's Disease)
05/2005
1Parkinsonian Disorders (Parkinsonism)
05/2005
1Ischemia
09/2003
1Infarction (Infarctions)
09/2003
1Carcinoma (Carcinomatosis)
10/2001
1Brain Neoplasms (Brain Tumor)
10/2001
1Herpes Simplex
07/2001
1Hematologic Neoplasms (Hematological Malignancy)
07/2001
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
07/2001
1Hearing Disorders (Hearing Disorder)
06/2001
1Ototoxicity
06/2001
1Urinary Bladder Neoplasms (Bladder Cancer)
05/2001
1Neoplasm Metastasis (Metastasis)
03/2001
1Necrosis
03/2001
1Inflammation (Inflammations)
03/2001
1Sarcoma (Soft Tissue Sarcoma)
03/2001
1Seizures (Absence Seizure)
08/2000
1Temporal Lobe Epilepsy
08/2000
1Neurodegenerative Diseases (Neurodegenerative Disease)
03/2000

Drug/Important Bio-Agent (IBA)

2Apolipoprotein E2IBA
01/2008 - 07/2005
2beta-Galactosidase (Lactaid)IBA
03/2001 - 08/2000
1Apolipoprotein E3IBA
01/2008
1Apolipoprotein E4IBA
01/2008
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
05/2005
1Dopamine (Intropin)FDA LinkGeneric
05/2005
1NeurotoxinsIBA
05/2005
1Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
09/2003
1Prostate-Specific Antigen (Semenogelase)IBA
10/2001
1Neoplasm Antigens (Tumor Antigens)IBA
10/2001
1OvalbuminIBA
10/2001
1Proteins (Proteins, Gene)FDA Link
10/2001
1Therapeutic UsesIBA
10/2001
1Interleukin-2 (IL2)IBA
09/2001
1CytokinesIBA
09/2001
1Nerve Growth Factors (Neurotrophins)IBA
06/2001
1Cisplatin (Platino)FDA LinkGeneric
06/2001
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2001
1MethylcholanthreneIBA
03/2001
1Glutamate Receptors (Glutamate Receptor)IBA
08/2000

Therapy/Procedure

4Therapeutics
10/2001 - 03/2000
2Immunotherapy
10/2001 - 07/2001