Peter Faller Selected Research

Alzheimer Disease (Alzheimer's Disease)

1/2024	Restoring cellular copper homeostasis in Alzheimer disease: a novel peptide shuttle is internalized by an ATP-dependent endocytosis pathway involving Rab5- and Rab14-endosomes.
6/2023	Derivatization of the Peptidic Xxx-Zzz-His Motif toward a Ligand with Attomolar CuII Affinity under Maintaining High Selectivity and Fast Redox Silencing.
6/2023	Chasing the Elusive "In-Between" State of the Copper-Amyloid β Complex by X-ray Absorption through Partial Thermal Relaxation after Photoreduction.
10/2022	Development of Cu(ii)-specific peptide shuttles capable of preventing Cu-amyloid beta toxicity and importing bioavailable Cu into cells.
1/2021	Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis.
1/2021	Copper Imbalance in Alzheimer's Disease and Its Link with the Amyloid Hypothesis: Towards a Combined Clinical, Chemical, and Genetic Etiology.
1/2020	Reproducibility Problems of Amyloid-β Self-Assembly and How to Deal With Them.
10/2019	Copper-Targeting Approaches in Alzheimer's Disease: How To Improve the Fallouts Obtained from in Vitro Studies.
1/2019	Role of PTA in the prevention of Cu(amyloid-β) induced ROS formation and amyloid-β oligomerisation in the presence of Zn.
6/2018	N-Terminal Cu-Binding Motifs (Xxx-Zzz-His, Xxx-His) and Their Derivatives: Chemistry, Biology and Medicinal Applications.

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Peter Faller Research Topics

Disease

56	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 01/2005
12	Amyloid Plaque 10/2022 - 10/2006
10	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2024 - 06/2007
5	Parkinson Disease (Parkinson's Disease) 01/2021 - 05/2015
3	Neoplasms (Cancer) 02/2024 - 01/2022
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 10/2023 - 01/2021
1	Communicable Diseases (Infectious Diseases) 01/2024
1	Inflammation (Inflammations) 09/2022
1	Necrosis 01/2022
1	Neuroinflammatory Diseases 01/2021
1	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 10/2018
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 12/2017
1	Atrophy 01/2017
1	Synucleinopathies 01/2017
1	Amyloidosis 03/2009
1	Myocardial Ischemia (Ischemic Heart Diseases) 02/2007

Drug/Important Bio-Agent (IBA)

38	Peptides (Polypeptides)IBA 01/2024 - 09/2005
35	Amyloid (Amyloid Fibrils)IBA 06/2023 - 01/2005
19	IonsIBA 06/2023 - 06/2007
18	CopperIBA 01/2024 - 06/2007
16	MetalsIBA 06/2023 - 06/2007
12	Amyloid beta-PeptidesIBA 10/2022 - 09/2005
8	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2022 - 06/2008
8	ZincIBA 01/2019 - 06/2007
7	SynucleinsIBA 01/2021 - 05/2015
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2005
4	IronIBA 12/2017 - 12/2009
2	Chelating AgentsIBA 10/2023 - 10/2016
2	Prion ProteinsIBA 01/2021 - 12/2017
2	AntioxidantsIBA 06/2018 - 08/2016
2	Amino Acids FDA Link 01/2018 - 02/2015
1	ThiosemicarbazonesIBA 02/2024
1	Adenosine Triphosphate (ATP)IBA 01/2024
1	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 01/2024
1	peptide AIBA 09/2022
1	Glutathione Disulfide (GSSG)FDA LinkGeneric 01/2022
1	Superoxide Dismutase-1IBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	Protein AggregatesIBA 01/2019
1	Carrier Proteins (Binding Protein)IBA 01/2019
1	LigandsIBA 01/2019
1	Cysteine (L-Cysteine)FDA Link 10/2018
1	Amyloidogenic ProteinsIBA 12/2017
1	Coordination ComplexesIBA 12/2017
1	alpha-SynucleinIBA 01/2017
1	Protein Isoforms (Isoforms)IBA 01/2017
1	MetallothioneinIBA 01/2017
1	tau Proteins (tau Protein)IBA 01/2017
1	peptide IIBA 10/2016
1	Methionine (L-Methionine)FDA Link 01/2016
1	Complement System Proteins (Complement)IBA 05/2015
1	Pyrrolidonecarboxylic Acid (Pyroglutamic Acid)IBA 12/2012
1	Heme (Haem)IBA 01/2012
1	AlbuminsIBA 02/2007
1	CobaltIBA 02/2007
1	Human Serum Albumin FDA LinkGeneric 02/2007
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2005

Therapy/Procedure

3	Therapeutics 02/2024 - 10/2023
1	Electrodes (Electrode) 10/2018
1	Chelation Therapy (Therapy, Chelation) 06/2018