John Evankovich Selected Research

HMGB1 Protein (HMG1)

3/2011	Interferon regulatory factor 1 mediates acetylation and release of high mobility group box 1 from hepatocytes during murine liver ischemia-reperfusion injury.
12/2010	High mobility group box 1 release from hepatocytes during ischemia and reperfusion injury is mediated by decreased histone deacetylase activity.

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John Evankovich Research Topics

Disease

8	Inflammation (Inflammations) 04/2024 - 09/2011
6	Ischemia 09/2012 - 01/2010
5	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 03/2024 - 12/2019
5	Reperfusion Injury 09/2012 - 12/2010
3	COVID-19 12/2023 - 06/2022
3	Critical Illness (Critically Ill) 01/2021 - 12/2019
2	Infections 04/2024 - 03/2024
2	Respiratory Insufficiency (Respiratory Failure) 03/2024 - 08/2021
2	Bacterial Infections (Bacterial Infection) 03/2024 - 01/2021
2	Respiratory Sounds (Crackle) 12/2023 - 06/2022
2	Pneumonia (Pneumonitis) 06/2022 - 01/2020
2	Appendicitis 06/2012 - 08/2011
1	Respiratory Hypersensitivity 04/2024
1	Chronic Obstructive Pulmonary Disease (COPD) 04/2024
1	Carcinogenesis 04/2024
1	Lung Diseases (Lung Disease) 04/2024
1	Lung Neoplasms (Lung Cancer) 04/2024
1	Asthma (Bronchial Asthma) 04/2024
1	Human Influenza (Influenza) 03/2024
1	Hemorrhage 02/2024
1	Disease Progression 12/2023
1	Necrosis 12/2023
1	Heart Failure 08/2021
1	Virus Diseases (Viral Diseases) 04/2021
1	Diabetes Mellitus 01/2021
1	Hyperglycemia 01/2021
1	Dysbiosis 12/2020
1	Sepsis (Septicemia) 01/2020
1	Cystic Fibrosis (Mucoviscidosis) 01/2020
1	Cytokine Release Syndrome 01/2020
1	Lung Injury 01/2020
1	Acute Kidney Injury (Acute Renal Failure) 12/2019
1	Systemic Scleroderma (Systemic Sclerosis) 01/2018
1	HIV Infections (HIV Infection) 11/2017
1	Acute Lung Injury 01/2017
1	Hepatocellular Carcinoma (Hepatoma) 01/2012
1	Neoplasms (Cancer) 01/2012
1	Hypoxia (Hypoxemia) 03/2011
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2010

Drug/Important Bio-Agent (IBA)

9	Biomarkers (Surrogate Marker)IBA 03/2024 - 12/2019
4	CytokinesIBA 03/2024 - 07/2012
4	Oxygen (Dioxygen)IBA 12/2023 - 06/2022
3	LigandsIBA 03/2024 - 01/2010
3	Type I Tumor Necrosis Factor ReceptorsIBA 03/2024 - 01/2018
3	Interleukin-6 (Interleukin 6)IBA 12/2023 - 01/2018
3	RNA (Ribonucleic Acid)IBA 12/2023 - 01/2020
3	UbiquitinIBA 04/2021 - 01/2017
2	GlucocorticoidsIBA 03/2024 - 01/2021
2	Advanced Glycation End ProductsIBA 12/2023 - 01/2018
2	Histones (Histone)IBA 09/2013 - 09/2011
2	Transcription Factors (Transcription Factor)IBA 09/2012 - 03/2011
2	Interferon Regulatory Factor-1 (Interferon Regulatory Factor 1)IBA 01/2012 - 03/2011
2	Toll-Like Receptors (Toll-Like Receptor)IBA 09/2011 - 01/2010
2	Pattern Recognition ReceptorsIBA 09/2011 - 01/2010
2	HMGB1 Protein (HMG1)IBA 03/2011 - 12/2010
1	AerosolsIBA 04/2024
1	Chemokine CX3CL1IBA 03/2024
1	Interleukin-33IBA 01/2021
1	ProcalcitoninIBA 01/2021
1	Blood Glucose (Blood Sugar)IBA 01/2021
1	C-PeptideIBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	Insulin (Novolin)FDA Link 01/2021
1	Interleukin-1 (Interleukin 1)IBA 01/2021
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2021
1	16S Ribosomal RNAIBA 12/2020
1	Cell-Free Nucleic AcidsIBA 01/2020
1	Interleukin-3 (Interleukin 3)IBA 01/2020
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2018
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2018
1	ChemokinesIBA 11/2017
1	Chemokine ReceptorsIBA 11/2017
1	CXC ChemokinesIBA 11/2017
1	Receptor for Advanced Glycation End ProductsIBA 01/2017
1	InflammasomesIBA 09/2013
1	Interferon Regulatory FactorsIBA 09/2012
1	Interferon Regulatory Factor-2 (Interferon Regulatory Factor 2)IBA 09/2012
1	Calcium-Calmodulin-Dependent Protein Kinase Type 4IBA 07/2012
1	InterferonsIBA 01/2012
1	DNA (Deoxyribonucleic Acid)IBA 09/2011
1	Proteins (Proteins, Gene)FDA Link 09/2011
1	Histone Deacetylases (Histone Deacetylase)IBA 12/2010

Therapy/Procedure

7	Artificial Respiration (Mechanical Ventilation) 12/2023 - 12/2019
4	Noninvasive Ventilation 12/2023 - 06/2022
4	Extracorporeal Membrane Oxygenation 12/2023 - 06/2022
3	Therapeutics 12/2023 - 12/2019
2	Appendectomy 06/2012 - 08/2011
2	Transplantation 01/2012 - 01/2010
1	Immunomodulation 11/2022
1	Length of Stay 06/2012