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Marc Engelhardt Selected Research

Mycoses (Diseases, Fungus)

1/2023Post-hoc analysis of the safety and efficacy of isavuconazole in older patients with invasive fungal disease from the VITAL and SECURE studies.
1/2019Variability and exposure-response relationships of isavuconazole plasma concentrations in the Phase 3 SECURE trial of patients with invasive mould diseases.
11/2018Treatment outcomes in patients with proven/probable vs possible invasive mould disease in a phase III trial comparing isavuconazole vs voriconazole.
7/2018Isavuconazole treatment for rare fungal diseases and for invasive aspergillosis in patients with renal impairment: Challenges and lessons of the VITAL trial.
1/2017Impact of Mucositis on Absorption and Systemic Drug Exposure of Isavuconazole.
7/2016Isavuconazole treatment for mucormycosis: a single-arm open-label trial and case-control analysis.
1/2016Isavuconazole Treatment of Cryptococcosis and Dimorphic Mycoses.

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Marc Engelhardt Research Topics

Disease

7Neoplasms (Cancer)
04/2024 - 11/2018
7Mycoses (Diseases, Fungus)
01/2023 - 01/2016
5Infections
10/2021 - 10/2017
4Aspergillosis
01/2019 - 01/2017
3Bacteremia
12/2023 - 01/2020
3Pneumonia (Pneumonitis)
01/2021 - 02/2019
2Healthcare-Associated Pneumonia
01/2021 - 07/2014
2Mucormycosis
01/2017 - 07/2016
1Carcinoma (Carcinomatosis)
04/2024
1Nausea
10/2023
1Body Weight (Weight, Body)
10/2023
1Glioblastoma (Glioblastoma Multiforme)
01/2023
1Lymphoma (Lymphomas)
01/2023
1Ovarian Neoplasms (Ovarian Cancer)
01/2023
1Stomatitis
11/2021
1Hand-Foot Syndrome
11/2021
1Cholangiocarcinoma
11/2021
1Ventilator-Associated Pneumonia
01/2021
1Endocarditis
01/2020
1Bacterial Pneumonia
11/2019
1Communicable Diseases (Infectious Diseases)
11/2019
1Chronic Obstructive Pulmonary Disease (COPD)
02/2019
1Invasive Candidiasis
01/2019
1Candidiasis (Moniliasis)
01/2019
1Candidemia
01/2019
1Neutropenia
01/2018
1Graft vs Host Disease (Graft-Versus-Host Disease)
10/2017
1Mucositis
01/2017
1Cryptococcosis
01/2016
1Bone Resorption
04/2008

Drug/Important Bio-Agent (IBA)

9isavuconazoleIBA
01/2023 - 01/2016
7ceftobiproleIBA
12/2023 - 02/2019
4lisavanbulinIBA
01/2023 - 01/2020
3Anti-Bacterial Agents (Antibiotics)IBA
10/2023 - 11/2017
3ProdrugsIBA
01/2023 - 07/2016
3Voriconazole (Vfend)FDA LinkGeneric
01/2019 - 10/2017
2derazantinibIBA
04/2024 - 11/2021
2AztreonamFDA LinkGeneric
10/2023 - 10/2021
2DaptomycinFDA Link
10/2023 - 01/2020
2BAL27862IBA
01/2023 - 10/2020
1atezolizumabIBA
04/2024
1Phosphotransferases (Kinase)IBA
04/2024
1Cephalosporins (Cephalosporin Antibiotics)IBA
10/2023
1PlatinumIBA
01/2023
1Pemetrexed (MTA)FDA Link
01/2023
1Investigational DrugsIBA
11/2021
1Retinaldehyde (Retinal)IBA
11/2021
1Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA
11/2021
1VancomycinFDA LinkGeneric
10/2021
1Lysine (L-Lysine)FDA Link
10/2020
1Adrenal Cortex Hormones (Corticosteroids)IBA
09/2019
1Caspofungin (Cancidas)FDA Link
01/2019
1Sodium Glutamate (Accent)IBA
11/2018
1LactamsIBA
11/2017
1BAL 30072IBA
11/2017
1posaconazoleFDA Link
10/2017
1Immunosuppressive Agents (Immunosuppressants)IBA
10/2017
1TriazolesIBA
10/2017
1Itraconazole (Sporanox)FDA LinkGeneric
10/2017
1Antifungal AgentsIBA
10/2017
1Cytochrome P-450 CYP3AIBA
10/2017
1Amphotericin B (Amphotericin)FDA LinkGeneric
07/2016
1Ceftazidime (Fortum)FDA LinkGeneric
07/2014
1Linezolid (Zyvox)FDA Link
07/2014
1ceftobiprole medocarilIBA
07/2014
1Biomarkers (Surrogate Marker)IBA
04/2008

Therapy/Procedure

4Therapeutics
02/2019 - 01/2017
1Mechanical Ventilators (Ventilator)
11/2019
1Critical Care (Surgical Intensive Care)
11/2019
1Hematopoietic Stem Cell Transplantation
10/2017