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Tim Elliott Selected Research

Neoplasms (Cancer)

1/2023Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology.
1/2023Reactivation of low avidity tumor-specific CD8+ T cells associates with immunotherapeutic efficacy of anti-PD-1.
1/2022Tapasin-mediated editing of the MHC I immunopeptidome is epitope specific and dependent on peptide off-rate, abundance, and level of tapasin expression.
1/2021The immunopeptidomes of two transmissible cancers and their host have a common, dominant peptide motif.
10/2020Time-resolved microwell cell-pairing array reveals multiple T cell activation profiles.
12/2019Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope.
1/2019HPV Epitope Processing Differences Correlate with ERAP1 Allotype and Extent of CD8+ T-cell Tumor Infiltration in OPSCC.
1/2018The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer.
1/2018A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules.
12/2015Plasticity of empty major histocompatibility complex class I molecules determines peptide-selector function.
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Tim Elliott Research Topics

Disease

16Neoplasms (Cancer)
01/2023 - 11/2002
8Infections
10/2023 - 06/2004
4Skin Neoplasms (Skin Cancer)
08/2012 - 01/2004
3Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 01/2004
3Crohn Disease (Crohn's Disease)
01/2020 - 10/2008
2Orofacial Granulomatosis
01/2020 - 01/2011
2Ankylosing Spondylitis
12/2014 - 02/2014
2Melanoma (Melanoma, Malignant)
11/2011 - 01/2004
1Alzheimer Disease (Alzheimer's Disease)
12/2022
1Human Influenza (Influenza)
01/2022
1Hypersensitivity (Allergy)
01/2021
1Acquired Immunodeficiency Syndrome (AIDS)
11/2020
1Dehydration (Water Stress)
10/2019
1AIDS-Related Complex (ARC)
10/2019
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2019
1Malaria
11/2018
1Necrosis
01/2017
1Disease Progression
10/2011
1Virus Diseases (Viral Diseases)
10/2011
1Fistula
10/2008
1Carcinoma (Carcinomatosis)
04/2007
1Testicular Neoplasms (Testicular Cancer)
01/2007
1Breast Neoplasms (Breast Cancer)
01/2007
1Vaccinia
01/2006
1Basal Cell Carcinoma (Rodent Ulcer)
01/2004
1Pain (Aches)
01/2004
1Bowen's Disease (Disease, Bowen)
01/2004
1Erythema
01/2004
1Autoimmune Diseases (Autoimmune Disease)
11/2002

Drug/Important Bio-Agent (IBA)

13Peptides (Polypeptides)IBA
01/2023 - 02/2008
7Histocompatibility Antigens Class IIBA
01/2022 - 02/2008
6VaccinesIBA
01/2023 - 06/2004
6AntigensIBA
01/2023 - 11/2002
5EpitopesIBA
01/2023 - 01/2019
2InterferonsIBA
10/2023 - 01/2017
2CytokinesIBA
10/2023 - 01/2017
2Proteins (Proteins, Gene)FDA Link
01/2022 - 12/2015
2tapasinIBA
01/2022 - 11/2020
2HLA Antigens (Human Leukocyte Antigens)IBA
01/2022 - 12/2019
2Glycoproteins (Glycoprotein)IBA
12/2019 - 04/2007
2Neoplasm Antigens (Tumor Antigens)IBA
12/2019 - 11/2002
2HLA-B27 Antigen (HLA B27 Antigen)IBA
12/2014 - 02/2014
2LigandsIBA
09/2012 - 02/2008
1IsotopesIBA
12/2022
1T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
01/2022
1Influenza Vaccines (Influenza Vaccine)FDA Link
01/2022
1Immunodominant EpitopesIBA
01/2022
1PiperazineIBA
10/2021
1FenbendazoleIBA
10/2021
1Levamisole (Decaris)FDA Link
10/2021
1abacavir (Ziagen)FDA Link
01/2021
1HLA-B57 antigenIBA
01/2021
1Ustekinumab (CNTO 1275)FDA Link
01/2020
1serpentine (alkaloid)IBA
10/2019
1Complement System Proteins (Complement)IBA
10/2019
1MolybdenumIBA
10/2019
1Histocompatibility Antigens Class IIIBA
11/2018
11- acetyl- 1,2,3,3a,8,8a- hexahydro- 8a- hydroxy- 5- methoxypyrrolo(2,3- b)indole (CHMI)IBA
11/2018
1AnthelminticsIBA
07/2017
1AminopeptidasesIBA
02/2014
1Arginine (L-Arginine)FDA Link
02/2014
1leucinethiolIBA
06/2013
1Viral AntigensIBA
09/2012
1Neuraminidase (Sialidase)IBA
09/2012
1SteroidsIBA
10/2008
1Thioguanine (Tioguanine)FDA Link
10/2008
1Infliximab (Remicade)FDA Link
10/2008
1NK Cell Lectin-Like Receptor Subfamily CIBA
01/2006
1DNA VaccinesIBA
06/2004
11-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2004
1Monoclonal AntibodiesIBA
01/2004
1AutoantigensIBA
11/2002

Therapy/Procedure

3Mohs Surgery (Mohs' Micrographic Surgery)
08/2012 - 05/2011
2Immunotherapy
01/2023 - 06/2013
2Therapeutics
06/2013 - 01/2011
1Lasers (Laser)
05/2011
1Analgesia
01/2004
1Photochemotherapy (Photodynamic Therapy)
01/2004
1Aftercare (After-Treatment)
01/2004