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Michel Eichelbaum Selected Research

Propafenone (Rythmol)

10/2006A silent mutation (2939G>A, exon 6; CYP2D6*59) leading to impaired expression and function of CYP2D6.

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Michel Eichelbaum Research Topics

Disease

14Breast Neoplasms (Breast Cancer)
03/2018 - 09/2002
5Neoplasms (Cancer)
12/2010 - 07/2002
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
08/2009 - 01/2005
2Drug-Related Side Effects and Adverse Reactions
01/2021 - 08/2002
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
10/2005 - 08/2002
1Lung Neoplasms (Lung Cancer)
10/2011
1Liver Diseases (Liver Disease)
07/2011
1Genetic Predisposition to Disease (Genetic Predisposition)
07/2011
1Chemical and Drug Induced Liver Injury
07/2011
1Glioblastoma (Glioblastoma Multiforme)
12/2010
1Leukemia
12/2010
1Acquired Immunodeficiency Syndrome (AIDS)
09/2010
1Hot Flashes
10/2009
1Brain Neoplasms (Brain Tumor)
08/2009
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2009
1Carcinogenesis
07/2008
1Diarrhea
05/2008
1Leukopenia
05/2008
1Mucositis
05/2008
1Colonic Neoplasms (Colon Cancer)
11/2007
1Hepatocellular Carcinoma (Hepatoma)
10/2006
1Carcinoma (Carcinomatosis)
05/2006
1Crohn Disease (Crohn's Disease)
10/2005
1Malaria
06/2005
1Residual Neoplasm
03/2005
1Hypertension (High Blood Pressure)
01/2005
1Colitis
01/2003
1Ulcerative Colitis
01/2003
1Nervous System Diseases (Neurological Disorders)
10/2002
1Parkinson Disease (Parkinson's Disease)
10/2002
1Pancytopenia
08/2002
1Kidney Neoplasms (Kidney Cancer)
07/2002

Drug/Important Bio-Agent (IBA)

11TamoxifenFDA LinkGeneric
03/2018 - 11/2007
8Cytochrome P-450 CYP2D6 (CYP2D6)IBA
01/2021 - 10/2006
5Messenger RNA (mRNA)IBA
12/2010 - 05/2006
4Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2021 - 01/2005
4Estrogen ReceptorsIBA
03/2018 - 12/2008
4EnzymesIBA
10/2011 - 03/2005
4Hormones (Hormone)IBA
09/2010 - 01/2008
34-hydroxy-N-desmethyltamoxifenIBA
01/2017 - 11/2007
3DNA (Deoxyribonucleic Acid)IBA
12/2010 - 07/2008
3Cytochrome P-450 CYP3AIBA
09/2010 - 01/2005
3thiopurine methyltransferase (thiopurine S-methyltransferase)IBA
08/2009 - 08/2002
3Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2003 - 07/2002
2Estrogens (Estrogen)FDA Link
03/2018 - 07/2008
2Biomarkers (Surrogate Marker)IBA
12/2010 - 01/2008
2Estrogen Receptor alphaIBA
12/2010 - 12/2008
2RNA (Ribonucleic Acid)IBA
12/2010 - 05/2006
2afimoxifene (hydroxytamoxifen)IBA
10/2009 - 11/2007
2SteroidsIBA
10/2009 - 01/2008
2Cytochrome P-450 CYP2C19IBA
11/2007 - 01/2002
2Azathioprine (Imuran)FDA LinkGeneric
10/2005 - 08/2002
2Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric
03/2005 - 08/2002
1IsoenzymesIBA
10/2011
1Anti-Infective Agents (Microbicides)IBA
07/2011
1Amoxicillin (Wymox)FDA LinkGeneric
07/2011
1Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric
07/2011
1Nucleic AcidsIBA
12/2010
1Progesterone Receptors (Progesterone Receptor)IBA
12/2010
1Metalloproteases (Metalloproteinases)IBA
12/2010
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2010
1Deoxyribonuclease I (Nickase)IBA
12/2010
1Epoxide HydrolasesIBA
12/2010
1Formaldehyde (Formol)FDA Link
12/2010
1ParaffinIBA
12/2010
1Xylenes (Xylene)IBA
12/2010
1efavirenz (Sustiva)FDA Link
09/2010
1Cytochrome P-450 CYP2B6 (CYP2B6)IBA
09/2010
1Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
10/2009
1Paroxetine (Paxil)FDA LinkGeneric
10/2009
1Fluoxetine (Prozac)FDA LinkGeneric
10/2009
1Cytochrome P-450 CYP2D6 InhibitorsIBA
10/2009
12-mercaptopurineIBA
08/2009
1Catechol EstrogensIBA
07/2008
1Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA
07/2008
1Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
05/2008
1Fluorouracil (Carac)FDA LinkGeneric
05/2008
1Thymidylate SynthaseIBA
05/2008
1Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA
05/2008
1Rifampin (Rifampicin)FDA LinkGeneric
11/2007
1Propafenone (Rythmol)FDA LinkGeneric
10/2006
1Mixed Function Oxygenases (Monooxygenases)IBA
10/2006
1Proteins (Proteins, Gene)FDA Link
10/2006
1triphosphoric acid (triphosphate)IBA
10/2005
16-thioguanosineIBA
10/2005
1Diphosphates (Pyrophosphates)IBA
10/2005
1artemisinin (artemisinine)IBA
06/2005
1Antimalarials (Antimalarial Agents)IBA
06/2005
1Codon (Codons)IBA
01/2005
1Anti-Bacterial Agents (Antibiotics)IBA
01/2003
1XenobioticsIBA
10/2002
1Doxorubicin (Adriamycin)FDA LinkGeneric
09/2002
1Etoposide (VP 16)FDA LinkGeneric
09/2002
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
09/2002
1Immunosuppressive Agents (Immunosuppressants)IBA
08/2002
1Omeprazole (Prilosec)FDA LinkGeneric
01/2002

Therapy/Procedure

9Therapeutics
03/2018 - 08/2002
2Aftercare (After-Treatment)
08/2009 - 03/2005
2Drug Therapy (Chemotherapy)
03/2005 - 09/2002
1Lasers (Laser)
09/2010