Gillian Douglas Selected Research

Hydroxychloroquine (Plaquenil)

10/2015

Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current If: Novel electrophysiological insights and therapeutic potential.

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Gillian Douglas Research Topics

Disease

11	Atherosclerosis 01/2023 - 09/2008
5	Inflammation (Inflammations) 01/2018 - 05/2010
4	Bradycardia 11/2017 - 03/2012
4	Vascular Diseases (Vascular Disease) 03/2015 - 05/2010
3	Phenylketonurias (Phenylketonuria) 01/2023 - 03/2012
3	Hypoxia (Hypoxemia) 10/2021 - 07/2013
3	Aortic Aneurysm (Aneurysm, Aortic) 01/2018 - 03/2015
3	Vascular Remodeling 01/2018 - 09/2013
3	Vascular System Injuries 06/2015 - 09/2008
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 06/2014
2	Reperfusion Injury 01/2023 - 01/2023
2	Neoplasms (Cancer) 10/2021 - 01/2018
2	Insulin Resistance 01/2020 - 12/2008
2	Obesity 01/2019 - 10/2014
2	Rupture 01/2018 - 03/2015
2	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 01/2017 - 11/2016
2	Hyperplasia 03/2016 - 09/2013
1	Movement Disorders (Movement Disorder) 05/2023
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2023
1	Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced) 01/2023
1	Medically Unexplained Symptoms 01/2023
1	Cardiomyopathies (Cardiomyopathy) 01/2023
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2023
1	Cardiomegaly (Heart Hypertrophy) 01/2023
1	Infarction (Infarctions) 01/2023
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2023
1	Pheochromocytoma 10/2021
1	Paraganglioma (Paragangliomas) 10/2021
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2020
1	Abdominal Aortic Aneurysm 01/2018
1	Aneurysm (Aneurysms) 01/2018
1	Inborn Genetic Diseases (Disease, Hereditary) 11/2016
1	Hypersensitivity (Allergy) 06/2015
1	Body Weight (Weight, Body) 10/2014
1	Hypertrophy 10/2014
1	Aortic Dissection 06/2014
1	Neointima 11/2013
1	Atherosclerotic Plaque (Atheroma) 04/2012
1	Tachycardia (Tachyarrhythmias) 03/2012

Drug/Important Bio-Agent (IBA)

9	sapropterin (tetrahydrobiopterin)FDA Link 05/2023 - 09/2008
7	Apolipoproteins E (ApoE)IBA 01/2023 - 09/2008
6	Angiotensin IIIBA 01/2018 - 04/2012
5	EnzymesIBA 05/2023 - 09/2008
4	Mixed Function Oxygenases (Monooxygenases)IBA 10/2021 - 07/2013
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2020 - 09/2008
4	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2014 - 09/2008
3	GTP Cyclohydrolase (GTP Cyclohydrolase I)IBA 09/2013 - 09/2008
2	Guanosine Triphosphate (GTP)IBA 05/2023 - 01/2023
2	Nitric Oxide Synthase (NO Synthase)IBA 01/2023 - 09/2013
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 10/2014
2	Oxygen (Dioxygen)IBA 10/2021 - 07/2013
2	Insulin (Novolin)FDA Link 01/2020 - 12/2008
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2019 - 04/2012
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 04/2012
2	LDL CholesterolIBA 01/2017 - 11/2016
2	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 03/2016 - 07/2013
2	ApolipoproteinsIBA 09/2013 - 05/2010
2	Superoxides (Superoxide)IBA 04/2012 - 09/2008
1	ActininIBA 01/2023
1	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 01/2023
1	UbiquitinIBA 01/2023
1	Vasodilator Agents (Vasodilators)IBA 01/2023
1	Long-Acting Insulin (Insulin, Long Acting)FDA Link 01/2020
1	Insulin Receptor Substrate ProteinsIBA 01/2020
1	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 01/2020
1	Frizzled ReceptorsIBA 01/2019
1	AdipokinesIBA 01/2019
1	WD repeat containing planar cell polarity effectorIBA 01/2019
1	Phosphotransferases (Kinase)IBA 01/2018
1	LDL Receptors (LDL Receptor)IBA 01/2017
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017
1	Bromodeoxyuridine (BrdU)IBA 03/2016
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 10/2015
1	RNA (Ribonucleic Acid)IBA 06/2015
1	MicroRNAs (MicroRNA)IBA 06/2015
1	ChemokinesIBA 03/2015
1	Chemokine ReceptorsIBA 03/2015
1	Levodopa (L Dopa)FDA LinkGeneric 03/2015
1	Glucose (Dextrose)FDA LinkGeneric 10/2014
1	GlycogenIBA 10/2014
1	Adenine NucleotidesIBA 10/2014
1	malonyl-CoA decarboxylaseIBA 10/2014
1	Aromatic Amino Acids (Aromatic Amino Acid)IBA 06/2014
1	Protein Isoforms (Isoforms)IBA 06/2014
1	MetalsIBA 11/2013
1	Paclitaxel (Taxol)FDA LinkGeneric 11/2013
1	Propranolol (Inderal)FDA LinkGeneric 03/2012
1	Adrenergic Agents (Adrenergic Drugs)IBA 03/2012
1	LipidsIBA 05/2010
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 05/2010
1	Insulin ReceptorIBA 12/2008

Therapy/Procedure

2	Drug-Eluting Stents 06/2015 - 11/2013
2	Stents 06/2015 - 11/2013
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2020
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2018
1	Endurance Training 11/2017
1	Vagus Nerve Stimulation 03/2012