Seamas C Donnelly Selected Research

Cystic Fibrosis (Mucoviscidosis)

10/2021	Role of extracellular vesicles in chronic lung disease.
1/2021	Early Interleukin-22 and Neutrophil Proteins Are Correlated to Future Lung Damage in Children With Cystic Fibrosis.
11/2017	Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis.
1/2017	Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections.
4/2016	Ivacaftor-Induced Proteomic Changes Suggest Monocyte Defects May Contribute to the Pathogenesis of Cystic Fibrosis.
7/2012	Macrophage migration inhibitory factor enzymatic activity, lung inflammation, and cystic fibrosis.
12/2005	Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism.

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Seamas C Donnelly Research Topics

Disease

7	Cystic Fibrosis (Mucoviscidosis) 10/2021 - 12/2005
6	Infections 01/2023 - 01/2017
6	Neoplasms (Cancer) 01/2023 - 09/2006
6	Pulmonary Fibrosis (Fibrosing Alveolitis) 09/2015 - 06/2007
5	Asthma (Bronchial Asthma) 03/2024 - 07/2007
4	Lung Neoplasms (Lung Cancer) 01/2023 - 04/2015
4	COVID-19 01/2023 - 01/2023
4	Disease Progression 01/2022 - 10/2002
4	Lung Diseases (Lung Disease) 10/2021 - 07/2007
4	Chronic Obstructive Pulmonary Disease (COPD) 10/2021 - 01/2010
3	Inflammation (Inflammations) 01/2023 - 03/2007
3	Idiopathic Pulmonary Fibrosis 01/2022 - 12/2013
2	Sarcoidosis (Schaumann Disease) 04/2024 - 01/2019
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 03/2003
2	Pneumonia (Pneumonitis) 01/2022 - 07/2012
2	Pseudomonas Infections 01/2022 - 01/2022
2	Hypoxia (Hypoxemia) 10/2020 - 09/2006
2	Stroke (Strokes) 12/2019 - 06/2019
2	Carcinogenesis 05/2016 - 06/2008
2	Fibrosis (Cirrhosis) 04/2015 - 02/2015
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 12/2002 - 10/2002
1	Hyperplasia 01/2023
1	Bacterial Infections (Bacterial Infection) 01/2022
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2021
1	Pulmonary Hypertension 10/2020
1	Retinoblastoma (Glioblastoma, Retinal) 09/2020
1	Neoplasm Metastasis (Metastasis) 05/2016
1	Lung Injury 08/2015
1	Asbestosis 02/2015
1	Rheumatoid Arthritis 02/2015
1	Emphysema 02/2015
1	Disease Susceptibility (Diathesis) 02/2011
1	Heart Failure 02/2009
1	Breast Neoplasms (Breast Cancer) 06/2008
1	Adenocarcinoma 06/2008
1	Newborn Respiratory Distress Syndrome 01/2008
1	Bronchiectasis 07/2007
1	Diastolic Heart Failure 02/2007
1	Atherosclerosis 03/2003

Drug/Important Bio-Agent (IBA)

13	Macrophage Migration-Inhibitory FactorsIBA 03/2024 - 12/2005
6	CytokinesIBA 03/2024 - 03/2003
3	Proteins (Proteins, Gene)FDA Link 04/2024 - 01/2021
3	CollagenIBA 01/2023 - 02/2007
3	Biomarkers (Surrogate Marker)IBA 10/2021 - 06/2007
2	3-(2'-methylphenyl)isocoumarinIBA 01/2023 - 04/2015
2	Toll-Like Receptor 3IBA 01/2022 - 12/2013
2	ivacaftorIBA 01/2017 - 04/2016
2	Interleukin-13IBA 08/2015 - 04/2015
2	Bleomycin (Blenoxane)FDA LinkGeneric 04/2015 - 12/2013
1	68Ga-FAPIIBA 04/2024
1	InflammasomesIBA 01/2023
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2023
1	Protein Isoforms (Isoforms)IBA 01/2022
1	Toll-Like Receptor AgonistsIBA 01/2022
1	FlagellinIBA 01/2022
1	16S Ribosomal RNAIBA 01/2022
1	Antiviral Agents (Antivirals)IBA 01/2022
1	AntibodiesIBA 01/2022
1	Drug CarriersIBA 10/2021
1	Interleukin-22 (IL-22)IBA 01/2021
1	MonocrotalineIBA 10/2020
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2019
1	tocilizumab (atlizumab)FDA Link 01/2019
1	SteroidsIBA 01/2019
1	GoldIBA 10/2018
1	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2017
1	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 05/2016
1	LigandsIBA 09/2015
1	SmokeIBA 02/2015
1	N 30IBA 02/2015
1	InterleukinsIBA 01/2014
1	AntigensIBA 01/2014
1	IronIBA 02/2011
1	Transforming Growth Factors (Transforming Growth Factor)IBA 02/2011
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2010
1	Peptide Hydrolases (Proteases)FDA Link 01/2010
1	Matrix Metalloproteinases (MMPs)IBA 01/2010
1	Double-Stranded RNA (RNA, Double Stranded)IBA 06/2008
1	Protein Kinases (Protein Kinase)IBA 06/2008
1	Messenger RNA (mRNA)IBA 06/2008
1	Small Interfering RNA (siRNA)IBA 06/2008
1	GlucocorticoidsIBA 07/2007
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2007
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 07/2007
1	ProteomeIBA 06/2007
1	5' Untranslated Regions (5' UTR)IBA 09/2006
1	ProcollagenIBA 12/2002
1	CXC ChemokinesIBA 12/2002
1	Interleukin-8 (Interleukin 8)IBA 10/2002
1	AutoantibodiesIBA 10/2002

Therapy/Procedure

10	Therapeutics 11/2023 - 06/2007
2	Immunotherapy 01/2023 - 01/2023
1	Artificial Respiration (Mechanical Ventilation) 01/2023
1	Critical Care (Surgical Intensive Care) 01/2023
1	Noninvasive Ventilation 01/2022
1	Precision Medicine 01/2021
1	Chinese Traditional Medicine (Traditional Chinese Medicine) 06/2019
1	Traction 02/2015