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Kosuke Doki Selected Research

Cytochrome P-450 CYP1A2 (CYP1A2)

6/2020Utilizing physiologically based pharmacokinetic modeling to predict theoretically conceivable extreme elevation of serum flecainide concentration in an anuric hemodialysis patient with cirrhosis.

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Kosuke Doki Research Topics

Disease

11Tachycardia (Tachyarrhythmias)
01/2022 - 09/2004
4Body Weight (Weight, Body)
10/2023 - 11/2006
2Neoplasms (Cancer)
01/2024 - 10/2022
2Hyperlipidemias (Hyperlipidemia)
12/2023 - 01/2022
2Ascites
10/2023 - 11/2022
2Breast Neoplasms (Breast Cancer)
01/2020 - 01/2009
1Infections
01/2024
1Gastrointestinal Neoplasms (Gastrointestinal Cancer)
10/2023
1Neoplasm Metastasis (Metastasis)
11/2022
1Stomach Neoplasms (Stomach Cancer)
11/2022
1Opioid-Induced Constipation
10/2022
1Cancer Pain
10/2022
1Colonic Neoplasms (Colon Cancer)
12/2021
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
05/2021
1Aplastic Anemia (Anemia, Hypoplastic)
05/2021
1Chronic Kidney Failure (Chronic Renal Failure)
06/2020
1Fibrosis (Cirrhosis)
06/2020
1Drug-Related Side Effects and Adverse Reactions
01/2020
1Thyroid Neoplasms (Thyroid Cancer)
01/2020
1Exanthema (Rash)
12/2018
1Diarrhea
12/2018
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2018
1Atrial Fibrillation
11/2018
1Achlorhydria (Hypochlorhydria)
11/2017
1Autoimmune Diseases (Autoimmune Disease)
04/2009
1Hypercholesterolemia
04/2009
1Oral Candidiasis (Thrush)
04/2009

Drug/Important Bio-Agent (IBA)

10Flecainide (Tambocor)FDA LinkGeneric
06/2020 - 09/2004
2Lipoproteins (Lipoprotein)IBA
12/2023 - 01/2022
2Monoclonal AntibodiesIBA
10/2023 - 11/2022
2Immunoglobulin G (IgG)IBA
10/2023 - 11/2022
2RamucirumabIBA
10/2023 - 11/2022
2Anti-Arrhythmia AgentsIBA
06/2020 - 10/2007
2Proton Pump InhibitorsIBA
12/2018 - 11/2017
2Cytochrome P-450 CYP2D6 (CYP2D6)IBA
07/2009 - 11/2006
1Rituximab (Mabthera)FDA Link
01/2024
1NivolumabIBA
11/2022
1Opioid Analgesics (Opioids)IBA
10/2022
1naldemedineIBA
10/2022
1Triglycerides (Triacylglycerol)IBA
01/2022
1LipidsIBA
01/2022
1Amiodarone (Amiodarona)FDA LinkGeneric
01/2022
1Bevacizumab (Avastin)FDA Link
12/2021
1Thrombopoietin ReceptorsIBA
05/2021
1eltrombopagFDA Link
05/2021
1Inosine Triphosphate (ITP)IBA
05/2021
15-hydroxypropafenoneIBA
12/2020
1Propafenone (Rythmol)FDA LinkGeneric
12/2020
1Mexiletine (Mexitil)FDA LinkGeneric
06/2020
1Cytochrome P-450 CYP1A2 (CYP1A2)IBA
06/2020
1TamoxifenFDA LinkGeneric
01/2020
1lenvatinibIBA
01/2020
1Erlotinib Hydrochloride (CP 358,774)FDA Link
12/2018
1Uremic ToxinsIBA
11/2018
1indoxylIBA
11/2018
1Thyroxine (Levothyroxine)FDA LinkGeneric
11/2017
1Nifedipine (Adalat)FDA LinkGeneric
11/2017
1Prednisolone (Predate)FDA LinkGeneric
04/2009
1GlucocorticoidsIBA
04/2009
1Lansoprazole (Prevacid)FDA LinkGeneric
01/2009
1Proteins (Proteins, Gene)FDA Link
01/2009
1Omeprazole (Prilosec)FDA LinkGeneric
01/2009
1Pantoprazole (Protonix)FDA LinkGeneric
01/2009
1Rabeprazole (Aciphex)FDA Link
01/2009
1CreatinineIBA
11/2006

Therapy/Procedure

1Hematopoietic Stem Cell Transplantation
01/2024
1Drug Therapy (Chemotherapy)
01/2024
1Renal Dialysis (Hemodialysis)
06/2020
1Catheter Ablation
11/2018