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Liufu Deng Selected Research

Immunotherapy

1/2024TIM-3 inhibitors: a promising strategy for tumor immunotherapy.
1/2024Cell-intrinsic PD-L1 ablation sustains effector CD8+ T cell responses and promotes antitumor T cell therapy.
1/2024Chemotherapy-free radiotherapy combined with immune checkpoint inhibitors: a new regimen for locally advanced non-small cell lung cancer?
12/2023Noncanonical MAVS signaling restrains dendritic cell-driven antitumor immunity by inhibiting IL-12.
6/2023Photochemically controlled activation of STING by CAIX-targeting photocaged agonists to suppress tumor cell growth.
1/2023STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells.
12/2022Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity.
1/2021Anti-PD-(L)1 immunotherapy for brain metastases in non-small cell lung cancer: Mechanisms, advances, and challenges.
1/2020cGAS-STING-mediated DNA sensing maintains CD8+ T cell stemness and promotes antitumor T cell therapy.
8/2010The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity.

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Liufu Deng Research Topics

Disease

21Neoplasms (Cancer)
01/2024 - 08/2010
11Bites and Stings (Sting)
06/2023 - 11/2014
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2024 - 01/2021
2Inflammation (Inflammations)
10/2021 - 11/2017
1Thrombosis (Thrombus)
01/2023
1Sepsis (Septicemia)
01/2023
1Brain Neoplasms (Brain Tumor)
01/2021
1Carcinogenesis
01/2014
1Infections
01/2014
1Diarrhea
01/2014
1Obesity
10/2012
1Thinness
10/2012

Drug/Important Bio-Agent (IBA)

9DNA (Deoxyribonucleic Acid)IBA
01/2023 - 11/2014
6Interferon Type IIBA
01/2023 - 11/2014
4Proteins (Proteins, Gene)FDA Link
12/2023 - 11/2014
4CytokinesIBA
06/2023 - 06/2013
4cyclic guanosine monophosphate-adenosine monophosphateIBA
01/2023 - 11/2014
3InterferonsIBA
06/2023 - 01/2021
2Immune Checkpoint InhibitorsIBA
01/2024 - 09/2013
2Mitochondrial DNA (mtDNA)IBA
01/2023 - 01/2017
2Transcription Factors (Transcription Factor)IBA
01/2020 - 01/2014
2Therapeutic UsesIBA
01/2018 - 10/2015
1RNA (Ribonucleic Acid)IBA
12/2023
1Antiviral Agents (Antivirals)IBA
12/2023
1Messenger RNA (mRNA)IBA
06/2023
1NF-kappa B (NF-kB)IBA
06/2023
1Carbonic Anhydrase InhibitorsIBA
06/2023
1Peptides (Polypeptides)IBA
01/2023
1Androgen Receptors (Androgen Receptor)IBA
12/2022
1Glucose (Dextrose)FDA LinkGeneric
01/2022
1Caspase 8 (Caspase-8)IBA
10/2021
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021
1AntibodiesIBA
01/2021
1Peptide Hydrolases (Proteases)FDA Link
01/2021
1NADPH Oxidases (NAD(P)H oxidase)IBA
01/2017
1Blocking AntibodiesIBA
10/2015
1B7-H1 AntigenIBA
02/2014
1Interleukin-17 (Interleukin 17)IBA
01/2014
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2014
1Interleukin-22 (IL-22)IBA
01/2014
1LigandsIBA
01/2014
1Lymphotoxin-alpha (Lymphotoxin)IBA
10/2012

Therapy/Procedure

10Immunotherapy
01/2024 - 08/2010
8Radiotherapy
01/2024 - 06/2013
5Therapeutics
01/2020 - 08/2010
1Chemoradiotherapy
01/2024
1Drug Therapy (Chemotherapy)
01/2024
1Ligation
01/2023
1Punctures
01/2023
1Castration
12/2022
1Transplantation
10/2012