Changchun Deng Selected Research

Therapeutics

1/2019	Targeting Translation of mRNA as a Therapeutic Strategy in Cancer.
1/2018	Umbralisib, a novel PI3Kδ and casein kinase-1ε inhibitor, in relapsed or refractory chronic lymphocytic leukaemia and lymphoma: an open-label, phase 1, dose-escalation, first-in-human study.
11/2016	High rate of complete responses to immune checkpoint inhibitors in patients with relapsed or refractory Hodgkin lymphoma previously exposed to epigenetic therapy.
1/2016	Will new drugs change the standard of care for patients with mantle cell lymphoma?
12/2005	Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae.

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Changchun Deng Research Topics

Disease

12	Neoplasms (Cancer) 01/2021 - 12/2005
7	Hodgkin Disease (Hodgkin's Disease) 12/2020 - 01/2013
7	Lymphoma (Lymphomas) 09/2020 - 01/2013
6	T-Cell Lymphoma (Lymphoma, T Cell) 01/2021 - 01/2015
3	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 02/2021 - 01/2018
2	Exanthema (Rash) 01/2020 - 01/2018
2	Neutropenia 01/2020 - 01/2018
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2018 - 01/2017
2	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2017 - 01/2015
1	Testicular Neoplasms (Testicular Cancer) 01/2021
1	Ataxia Telangiectasia (Louis Bar Syndrome) 09/2020
1	Thrombocytopenia (Thrombopenia) 01/2020
1	Fatigue 01/2020
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2020
1	Multiple Myeloma 01/2020
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2020
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2019
1	Febrile Neutropenia 01/2018
1	Colitis 01/2018
1	Infections 01/2018
1	Pneumonia (Pneumonitis) 01/2018
1	Stomatitis 01/2018
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2018
1	Sepsis (Septicemia) 01/2018
1	Leukemia 01/2017
1	Residual Neoplasm 01/2016
1	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 01/2013
1	Hypoxia (Hypoxemia) 12/2005

Drug/Important Bio-Agent (IBA)

5	Histone Deacetylase InhibitorsIBA 02/2021 - 01/2015
5	Brentuximab VedotinIBA 12/2020 - 01/2013
5	romidepsin (FK228)FDA Link 09/2020 - 01/2015
3	Bendamustine Hydrochloride FDA Link 12/2020 - 01/2018
3	10-propargyl-10-deazaaminopterin FDA Link 01/2018 - 05/2015
2	Proteins (Proteins, Gene)FDA Link 01/2019 - 12/2005
2	umbralisibIBA 01/2018 - 01/2017
1	belinostatIBA 02/2021
1	Prednisone (Sone)FDA LinkGeneric 02/2021
1	Vincristine (Oncovin)FDA LinkGeneric 02/2021
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 02/2021
1	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2021
1	MethyltransferasesIBA 01/2021
1	AntigensIBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	2- (2,6- dimethylmorpholin- 4- yl)- N- (5- (6- morpholin- 4- yl- 4- oxo- 4H- pyran- 2- yl)- 9H- thioxanthen- 2- yl)acetamideIBA 09/2020
1	CreatinineIBA 01/2020
1	Alanine Transaminase (SGPT)IBA 01/2020
1	Lenalidomide (CC 5013)FDA Link 01/2020
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2020
1	Azacitidine (5 Azacytidine)FDA Link 10/2019
1	Eukaryotic Initiation Factor-4EIBA 01/2019
1	HomoharringtonineIBA 01/2019
1	Messenger RNA (mRNA)IBA 01/2019
1	Tyrosine Kinase InhibitorsIBA 01/2019
1	Caseins (Casein)FDA Link 01/2018
1	Protein Isoforms (Isoforms)IBA 01/2017
1	Monoclonal AntibodiesIBA 01/2017
1	Proteasome InhibitorsIBA 01/2017
1	ublituximabIBA 01/2017
1	idelalisibIBA 01/2017
1	Rituximab (Mabthera)FDA Link 01/2017
1	carfilzomibIBA 01/2017
1	ibrutinibIBA 01/2017
1	Immune Checkpoint InhibitorsIBA 11/2016
1	LY2409881IBA 01/2015
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2015
1	Adenosine Triphosphate (ATP)IBA 01/2015
1	Phosphotransferases (Kinase)IBA 01/2015

Therapy/Procedure

5	Therapeutics 01/2019 - 12/2005
5	Drug Therapy (Chemotherapy) 01/2018 - 01/2013
2	Stem Cell Transplantation 11/2016 - 01/2013