Andrea Del Fattore Selected Research

Bone Resorption

2/2020	Bone Control of Muscle Function.
1/2020	The Role of Autophagy in Osteoclast Differentiation and Bone Resorption Function.
9/2019	The Endocrine Function of Osteocalcin Regulated by Bone Resorption: A Lesson from Reduced and Increased Bone Mass Diseases.
4/2014	CLCN7 and TCIRG1 mutations differentially affect bone matrix mineralization in osteopetrotic individuals.
6/2012	The tight relationship between osteoclasts and the immune system.
8/2011	Mechanisms inducing low bone density in Duchenne muscular dystrophy in mice and humans.
8/2010	Receptor activator of NF-kappaB ligand enhances breast cancer-induced osteolytic lesions through upregulation of extracellular matrix metalloproteinase inducer/CD147.
7/2010	Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism.
5/2008	Osteoclast receptors and signaling.
7/2006	Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: implications for therapy.

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Andrea Del Fattore Research Topics

Disease

10	Bone Resorption 02/2020 - 07/2006
7	Neoplasms (Cancer) 03/2024 - 08/2010
6	Neoplasm Metastasis (Metastasis) 03/2024 - 07/2006
6	Osteopetrosis 04/2014 - 08/2007
4	Prostatic Neoplasms (Prostate Cancer) 11/2022 - 04/2018
3	Osteosarcoma (Osteogenic Sarcoma) 03/2024 - 11/2021
2	Cystinosis 01/2023 - 01/2019
2	Essential Osteolysis 11/2022 - 01/2021
2	Rhabdomyosarcoma 10/2019 - 04/2019
2	Bone Diseases (Bone Disease) 09/2019 - 04/2018
2	Metabolic Bone Diseases (Osteopenia) 08/2011 - 03/2008
2	Breast Neoplasms (Breast Cancer) 08/2010 - 07/2006
1	Rare Diseases (Rare Disease) 01/2021
1	Sarcopenia 02/2020
1	Osteolysis 12/2019
1	Alveolar Rhabdomyosarcoma 04/2019
1	Fanconi Syndrome (Syndrome, Fanconi) 01/2019
1	Embryonal Rhabdomyosarcoma 10/2017
1	Glucose Intolerance 01/2017
1	Insulin Resistance 01/2017
1	Overweight 01/2017
1	Glioma (Gliomas) 01/2017
1	Poikiloderma with Neutropenia 01/2012
1	Primary Myelofibrosis (Myelosclerosis) 01/2010
1	Hypocalcemia 06/2009
1	Osteoporosis 06/2009
1	Secondary Hyperparathyroidism 06/2009
1	Osteosclerosis 03/2008
1	Growth Disorders 11/2006
1	Inflammation (Inflammations) 11/2006

Drug/Important Bio-Agent (IBA)

4	Proteins (Proteins, Gene)FDA Link 10/2019 - 03/2008
3	OsteocalcinIBA 02/2020 - 07/2010
3	Interleukin-6 (Interleukin 6)IBA 08/2011 - 07/2006
2	Biomarkers (Surrogate Marker)IBA 11/2022 - 11/2021
2	AntioxidantsIBA 01/2020 - 04/2019
2	MineralsIBA 01/2019 - 08/2011
2	Phosphotransferases (Kinase)IBA 10/2017 - 07/2006
2	Glucose (Dextrose)FDA LinkGeneric 01/2017 - 07/2010
2	CytokinesIBA 06/2012 - 07/2006
2	LigandsIBA 08/2010 - 08/2007
2	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 08/2010 - 05/2008
1	UbiquitinIBA 03/2024
1	Cysteamine (Mercaptamine)FDA Link 01/2023
1	GenisteinIBA 01/2023
1	Histone Deacetylase InhibitorsIBA 01/2023
1	AndrogensIBA 05/2021
1	Small Interfering RNA (siRNA)IBA 05/2021
1	MicroRNAs (MicroRNA)IBA 01/2021
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 02/2020
1	Hormones (Hormone)IBA 02/2020
1	Autophagy-Related ProteinsIBA 01/2020
1	E-SelectinIBA 12/2019
1	taxaneIBA 12/2019
1	Docetaxel (Taxotere)FDA Link 12/2019
1	Collagen Type I (Type I Collagen)IBA 12/2019
1	belinostatIBA 10/2019
1	Hydroxamic Acids (Hydroxamic Acid)IBA 10/2019
1	Radiation-Sensitizing AgentsIBA 10/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2019
1	Oxidants (Oxidizing Agents)IBA 04/2019
1	Cystine (L-Cystine)IBA 01/2019
1	SymportersIBA 01/2019
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 09/2018
1	trametinibIBA 09/2018
1	U 0126 (UO 126)IBA 09/2018
1	X480IBA 04/2018
1	Erythropoietin FDA Link 10/2017
1	EphrinsIBA 10/2017
1	ORALIT (ORS)IBA 01/2017
1	Triglycerides (Triacylglycerol)IBA 01/2017
1	Uric Acid (Urate)IBA 01/2017
1	CalciumIBA 04/2014
1	Vacuolar Proton-Translocating ATPases (V-Type ATPase)IBA 04/2014
1	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 03/2014
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2010
1	Matrix Metalloproteinases (MMPs)IBA 08/2010
1	Metalloproteases (Metalloproteinases)IBA 08/2010
1	Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA 08/2010
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 08/2010
1	Insulin (Novolin)FDA Link 07/2010
1	salicylhydroxamic acid (SHAM)IBA 01/2010
1	AcidsIBA 06/2009
1	Cholecystokinin B ReceptorIBA 06/2009
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 06/2009
1	Proton Pumps (Proton Pump)IBA 06/2009
1	IntegrinsIBA 05/2008
1	Cell Surface ReceptorsIBA 05/2008
1	OsteoprotegerinIBA 05/2008
1	RANK LigandIBA 05/2008
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 05/2008
1	platelet protein P47 (pleckstrin)IBA 03/2008
1	Alkaline PhosphataseIBA 03/2008
1	Tartrate-Resistant Acid PhosphataseIBA 03/2008
1	Conditioned Culture MediaIBA 03/2008
1	Protein Kinases (Protein Kinase)IBA 07/2006

Therapy/Procedure

5	Therapeutics 03/2024 - 07/2006
3	Drug Therapy (Chemotherapy) 03/2024 - 12/2019
3	Radiotherapy 01/2020 - 09/2018
2	Castration 11/2022 - 12/2019
1	Subcutaneous Injections 04/2018